A5027632013- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Vestibular and auditory disorders
- Epilepsy research and treatment
- Anesthesia and Sedative Agents
- Myasthenia Gravis and Thymoma
- Neurological disorders and treatments
- Ophthalmology and Eye Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroscience and Neuropharmacology Research
- Ion channel regulation and function
- Respiratory Support and Mechanisms
- Autoimmune Neurological Disorders and Treatments
- Tracheal and airway disorders
- Long-Term Effects of COVID-19
- Sleep and related disorders
- Cleft Lip and Palate Research
- Advanced MEMS and NEMS Technologies
- Circadian rhythm and melatonin
- Glycogen Storage Diseases and Myoclonus
- Sympathectomy and Hyperhidrosis Treatments
- Migraine and Headache Studies
- Inflammatory mediators and NSAID effects
- Smoking Behavior and Cessation
- Osteoarthritis Treatment and Mechanisms
Hospital Universitario de La Princesa
2017-2025
University Hospital HM Puerta del Sur
2022-2024
Hospital Universitario HM Sanchinarro
2022-2024
Universidad Autónoma de Madrid
2021
Hospital Universitario Fundación Jiménez Díaz
2021
Hospital Universitario Araba
2021
Hospital Clínico Universitario de Caracas
2007
Arizona State University
1999
Among patients affected by the virus COVID-19, physicians have observed ventilation disorders. It is relevant to assess neurological involvement, including role of diaphragmatic function. Its possible impairment could be related systemic inflammatory response and disease progression that both typify COVID-19 infection. We distinguished two groups (severe group (SG) mild (MG)) according severity respiratory symptomatology. performed neurophysiological sonography studies evaluate Regarding...
A variety of drugs have been used to activate and identify the epileptogenic area in patients during presurgical evaluation. We evaluated safety usefulness etomidate identifying epileptic zone by measuring bioelectrical brain activity cerebral blood flow (CBF).We studied 13 men 9 women under evaluation for temporal lobe epilepsy. applied (0.1 mg/kg) while were monitored video-electroencephalography (VEEG) with foramen ovale electrodes. In a subset 15 patients, we also measured CBF single...
Epilepsy is one of the major neurological disorders, affecting roughly 0.5-2% world's population and approximately 20-25% patients are resistant to medication.To analyze response cerebral perfusion (assessed by SPECT) bioelectrical activity (measured in scalp mesial temporal region) etomidate.We studied 10 presurgically evaluated video-EEG with foramen ovale electrodes (EFO) SPECT. Etomidate was administered (0.1 mg/kg), followed (99)mTc-HmPAO during study + EFO.The side-effects consisted...
Epilepsy is one of the major neurological disorders characterized by spontaneous and recurrent seizures. Despite progress in understanding epilepsy, exact network underlying seizures unclear.Actually role astrocytes modulation neuronal activity synaptic transmission clear, making as important players processing information central nervous system. These characteristics make us think that have an epileptogenesis. Disruption blood brain-barrier let pass albumin, it could uptake into astrocytes....
Subscription RequiredCase ReportsPropriospinal myoclonus: diagnostic value of polymyography and video polysomnography Rybel Wix Ramos, MD, PhD, Laura López Viñas, Esmeralda Rocio Martín, Cecilia Luque Cárdenas, Adela Fraile Pereda, Lydia Manzanares, MD PhD Address correspondence to: Wix, Department Clinical Neurophysiology, Sleep Unit, University Hospital “La Princesa”, Diego de León 62, 28006, Madrid, Spain; Tel: +34 915202213; Email: E-mail Address: [email protected] Spain Neurology, unit,...
Piribedil is a D2 D3 dopamine agonist, which has been shown to be well tolerated and improve Parkinsonian symptoms, particularly tremor. However, few studies have published about this Dopamine Agonist as an adjunct levodopa therapy in patients with Parkinson's disease (PD). This placebo controlled, parallel group study was undertaken investigate the effects of piribedil PD insufficiently controlled nine months follow up.We included 62 needed increase stimulation. Patients were randomized two...
Abstract A controlled-release (CR) form of diclofenac-potassium has been developed, which delivers 100 mg over the course 24 hours. This formulation is administered QD and provides steady plasmatic levels drug. The aim this study was to compare effectiveness tolerability CR versus immediate-release (IR) formulation, when used for treatment pain in patients with knee osteoarthritis. prospective, randomized, double-blind, comparative, multi-center, parallel-group conducted male female who had...
Presentamos un nuevo abordaje mínimamente invasivo mediante distracción intraoral de rama mandibular bilateral (bilateral internal ramus distraction) para el tratamiento del síndrome apnea obstructiva sueño en paciente adulto. Tras la planificación virtual 3 D, es intervenido bajo anestesia general y asistencia endoscópica, dentro protocolo cirugía mayor ambulatoria, dado alta mismo día cirugía. periodo 5 días, se alarga verticalmente durante que oscila entre 10 50 a ritmo 0,5 1 mm diario,...
Myasthenia gravis is a neuromuscular disease that causes weakness in skeletal muscles because of the presence acetylcholine receptor antibodies. These antibodies produce compromise end-plate potential, reducing safety factor for effective synaptic transmission. Clinically, this manifests as muscle and, severe cases, respiratory failure. There widespread knowledge about association between small cell lung carcinoma and Lambert- Eaton myasthenic syndrome, but not with other disorders, such...
Abstract Objective: To study the respiratory patterns and hemodynamic variations related to postural changes in inpatients with coronavirus disease (COVID-19). Methods: This report is a prospective cohort of admitted COVID-19. We recruited 10 patients hospital moderate or severe COVID-19 who showed improvement oxygen saturation prone positioning. performed cardiorespiratory polygraphy evaluations by thoracic electrical bioimpedance. Results: observed median minimum 85.00% (IQR: 7.00) supine...