- Migraine and Headache Studies
- Acute Ischemic Stroke Management
- Trigeminal Neuralgia and Treatments
- Psychosomatic Disorders and Their Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Obstructive Sleep Apnea Research
- Atrial Fibrillation Management and Outcomes
- Genetic Neurodegenerative Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Venous Thromboembolism Diagnosis and Management
- Autoimmune Neurological Disorders and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Epilepsy research and treatment
- Cardiovascular Syncope and Autonomic Disorders
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Eye Disorders
- Neurosurgical Procedures and Complications
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Brain Metastases and Treatment
- Cardiovascular and Diving-Related Complications
- Mitochondrial Function and Pathology
- Alcoholism and Thiamine Deficiency
- Neurological Complications and Syndromes
Hospital Universitario de La Princesa
2016-2025
Universidad Autónoma de Madrid
2020-2024
Sleep Research Society
2024
Hospital de Cruces
2013-2023
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021
Pain and Headache Center
2021
Clínica Sagrada Esperança
2020
The University of Tokyo
2019
Hospital Universitario del Henares
2018
Hospital de Santa Maria
2014
Anti-IgLON5 disease is a recently described neurologic that shares features of autoimmunity and neurodegeneration. Abnormal movements appear to be frequent important but have not been characterized are underreported. We describe the frequency types movement disorders in series consecutive patients with this disease.In retrospective, observational study, presence phenomenology were assessed standardized clinical questionnaire. Available videos centrally reviewed by 3 experts...
Abstract Background Anti-CGRP monoclonal antibodies have shown notable effectiveness and tolerability in migraine patients; however, data on their use elderly patients is still lacking, as clinical trials implicit age restrictions real-world evidence scarce. In this study, we aimed to describe the safety of erenumab, galcanezumab fremanezumab over 65 years old real-life. Methods observational real-life a retrospective analysis prospectively collected from 18 different headache units Spain...
Several variables have been reported to be associated with anti-calcitonin gene-related peptide (CGRP) receptor or ligand antibody response, but differing results. Our objective was determine whether machine-learning (ML)-based models can predict 6-, 9- and 12-month responses anti-CGRP therapies among migraine patients.We performed a multicenter analysis of prospectively collected data from patients receiving therapies. Demographic clinical were collected. Response rates in the 30% 50%...
Previous studies have demonstrated that emotional stress, changes in lifestyle habits and infections can worsen the clinical course of migraine. We hypothesize medical care during coronavirus disease 2019 (COVID-19) lockdown might worsened migraine.Retrospective survey study collecting online responses from migraine patients followed-up by neurologists at three tertiary hospitals between June July 2020.We used a web-based included demographic data, variables related with any headache...
Long-term real-life studies have supported a cumulative effect of OnabotulinumtoxinA (OnabotA) for the prophylactic treatment chronic migraine (CM) during consecutive cycles, and individual adaptations been described to improve clinical response.This was cohort longitudinal retrospective study adult patients from Headache Unit Hospital Clínico Universitario de Valladolid La Princesa (Madrid) on OnabotA May 2012 December 2017. All were followed 24 weeks. Full-length response defined as ≥50%...
Abstract Objective To evaluate clinical characteristics, effectiveness, and tolerability of preventive anti- calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) in the elderly. Anti-CGRP mAbs have demonstrated efficacy safety patients with migraine although there is limited information regarding Design We performed a multicenter case-control study cases (patients over 65 years old) controls (sex-matched under 55 receiving anti-CGRP mAbs. Methods included demographic...
According to the latest European guidelines, discontinuation of monoclonal antibodies against calcitonin gene-related peptide (anti-CGRP MAb) may be considered after 12-18 months treatment. However, some patients worsen discontinuation. In this study, we assessed response following treatment resumption.
Anti-calcitonin gene-related peptide (CGRP) therapies are recent preventive approved for both episodic and chronic migraine. One of the measures effectiveness is withdrawal other treatments. The objective this study to quantify impact anti-CGRP drugs in concomitant treatment patients with
Introduction The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) may mimic stroke when patients present acute/subacute focal deficits. It would be helpful to identify investigations that assist the neurologist in differentiating between HaNDL stroke. Case reports We describe three cases proved HaNDL, but were initially considered strokes. Hypoperfusion was noted CT perfusion (CTP) studies all cases, which extended beyond any single...
The aim of this study was to describe the clinical and epidemiological characteristics acute ischaemic stroke (AIS) in patients with atrial fibrillation (AF) previously treated oral anticoagulants (OACs) according type OAC prescribed. Also, analyze outcomes therapeutic approach adopted by neurologist phase for secondary prevention.We performed a multicenter, observational based on prospective registries. We included AF OACs admitted AIS over 1-year period. Detailed data functional outcome at...
Syphilis produces myriad nonspecific signs and symptoms. For example, optic disk swelling might be seen in patients with syphilis as a result of cranial hypertension (papilloedema), inflammatory neuritis papillitis, or perineuritis. We report case involving differential diagnosis syphilitic bilateral papillitis mimicking papilloedema.
Face-to-face procedures have been postponed during COVID-19 pandemic. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine Subjective worsening, intensity attacks, and frequency headache were retrospectively compared between patients with unmodified interrupted Headache Units. included 67 chronic or high-frequency episodic under treatment, 65 (97.0%) female, 44.5 ± 12.1 years old. Treatment administration was voluntarily delayed 14 (20.9%) nine (13.4%) unable...