A5077496821- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Gut microbiota and health
- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Eosinophilic Esophagitis
- Inflammatory Bowel Disease
- Gastric Cancer Management and Outcomes
- Food Drying and Modeling
- Microbial Inactivation Methods
- Clostridium difficile and Clostridium perfringens research
- Family and Disability Support Research
- Autism Spectrum Disorder Research
- Complementary and Alternative Medicine Studies
- Clinical Nutrition and Gastroenterology
- Pathogenesis and Treatment of Hiccups
- Barrier Structure and Function Studies
- Gout, Hyperuricemia, Uric Acid
- Dietary Effects on Health
- Healthcare and Environmental Waste Management
- Lower Extremity Biomechanics and Pathologies
- Microencapsulation and Drying Processes
- Acupuncture Treatment Research Studies
- Advances in Cucurbitaceae Research
- Behavioral and Psychological Studies
Xiyuan Hospital
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
China Academy of Chinese Medical Sciences
2023
Shanghai Sunshine Rehabilitation Center
2017-2022
Tongji University
2022
Northwest A&F University
2018-2020
UNSW Sydney
2013
Jiangnan University
2012
Chinese Academy of Sciences
2006
Objectives Cuproptosis is a recently discovered form of programmed cell death; however, its role in ulcerative colitis (UC) remains void. Methods Three gene expression profiles were acquired from the GEO database. Subsequently, single sample set enrichment analysis (ssGSEA) was performed to identify immune infiltration characteristics UC. Correlation between cuproptosis and further conducted, cuproptosis-related genes applied construct UC diagnostic model. results microarray data...
Atrophic gastritis (AG), which is characterized by a decreased number or disappearance of the glandular structures and secretory dysfunction, linked to chronically inflamed stomach. It has been estimated that annual incidence gastric cancer (GC) 0.1% for patients with AG. Early eradication Helicobacter pylori (H. pylori) can reduce risk GC development. Additionally, follow-up management AG are necessary prevent GC. Exploring novel methods automatized analysis data apprehending knowledge in...
There are about 10-23% of adults worldwide suffering from irritable bowel syndrome (IBS). Over the past few decades, there many aspects uncertainty regarding IBS leading to an ongoing interest in topic as reflected by a vast number publications, whose heterogeneity and variable quality may challenge researchers measure their scientific impact, identify collaborative networks, grasp actively researched themes. Accordingly, with help bibliometric approaches, our goal is assess structure,...
In this study, Chinese herbal compound prescriptions combined with medicine powder were evaluated for the treatment of chronic atrophic gastritis erosion.This multi-center, randomized, positive drug control clinical trial randomly assigned 216 patients erosion to three groups: (1) group: aluminum plus magnesium suspension thrice per day 4 weeks; (2) test group 1: twice a Sanqi (Panax notoginseng) (3) 2: and Zhebeimu (Fritillaria thunbergii Miq.) weeks. The primary endpoint (improvement...
Non-erosive reflux disease (NERD), the most frequent phenotype of gastroesophageal disease, presents without visible esophageal mucosal damage but significantly impacts patients' quality life. Current treatments like proton pump inhibitors show limited efficacy for many NERD patients, necessitating alternative approaches. Jianpi Qinghua (JQ) granules, a traditional Chinese medicine, have shown promise in treating by targeting symptoms spleen deficiency and damp-heat syndrome. This study aims...
Autism spectrum disorder (ASD) is a complicated diffuse developmental that commonly involves gastrointestinal distress and dysbacteriosis. Emerging lines of evidence have shown faecal microbiota transplantation (FMT) to be potential therapeutic strategy for improving the clinical outcomes patients with ASD by re-establishing their intestinal microflora. We are undertaking first-ever multicentre, double-blind, randomised controlled trial FMT treatment children both symptoms will assess...
Background Gastroesophageal reflux disease (GERD), a disorder resulting from the retrograde flow of gastric contents into esophagus, affects an estimated 10–30% Western population, which is characterized by multifactorial pathogenesis. Over past few decades, there have been many aspects uncertainty regarding GERD leading to ongoing interest in field as reflected large number publications, whose heterogeneity and variable quality may present challenge for researchers measure their scientific...
Background: Peer-mediated intervention (PMI) is an that teaches normally developing peers to help children with autism spectrum disorder (ASD) actively participate in social interactions. Previous studies have shown PMI applied school settings effective for ASD, but more multiple-baseline single-subject design. Many questions are still not clear due the large clinical variability ASD. This study investigated effectiveness of on skills ASD at varying symptom levels and analyzed specific...
Systematic reviews/meta-analyses (SRs/MAs) are still controversial on the effectiveness of Banxia Xiexin decoction (BXD) to treat gastroesophageal reflux disease (GERD). To assess evidence reliability and inform clinical use BXD, we performed a meta-analysis from previous SRs/MAs collate, critically appraise, synthesize BXD treatment in GERD.SRs/MAs were collected by searching major medical databases. The included studies evaluated terms methodological quality using criteria Assessment...
Proton pump inhibitors (PPIs) play an important role in the treatment of nonerosive reflux disease (NERD), but their long-term and excessive uses have been associated with safety concerns. Chinese herbal medicine (CHM) has become a popular alternative for this condition.A total 204 patients were randomly assigned to combination group or PPI (1:1 ratio). They given JianpiQinghua (JQ) granules (34.8 g) plus omeprazole (10 mg) dummy JQ (20 daily 4 weeks. The primary endpoints rate sufficient...
Ulcerative colitis (UC) is an autoimmune disease of the colon. The aim this study was to explore characteristics immune infiltrates in UC patients and identify immune-related diagnostic biomarkers for UC.Three gene expression profiles were acquired from GEO database, followed by identification differentially expressed genes (DEGs) Linear Modeling Microarray Data. Enrichment analysis Gene Ontology (GO), Kyoto Encyclopedia Genes Genomes (KEGG) Disease (DO) performed analyze biological...
Abstract Background Irritable bowel syndrome (IBS) has been gradually recognized as a disorder of the brain-gut interaction, but molecular changes in brain and colon that occur disease development remain poorly understood. We employed proteomic analysis to identify differentially expressed proteins both three IBS models. Methods To explore relevant protein abundance colon, isobaric tags for relative absolute quantitation (iTRAQ), liquid chromatography tandem mass spectrometry (LC-MS) Western...
BackgroundThe concept of the gut-liver axis was proposed by Marshall in 1998, and since then, this hypothesis has been gradually accepted academic community. Many publications have published on axis, making it important to assess scientific implications these studies trends field.MethodsPublications were retrieved from Web Science Core Collection. Microsoft Excel, CiteSpace, VOSviewer, Scimago Graphica software used for bibliometric analysis.ResultsA total 776 core database included study....
Background: The pathophysiology of functional dyspepsia (FD) remains insufficiently understood, and the pain economic constraints associated with endoscopic examinations hinder precise definition treatment this disorder. Exploring potential multi-omics biomarkers for FD could yield promising targets effectively diagnosing treating condition. Methods: We recruited 54 patients 29 healthy volunteers characterized their gut microbiota by shotgun metagenomic sequencing serum urine metabolites...
Using the shuttle vector pBU4, mosquitocidal toxin gene mtx1 from Bacillus sphaericus strain SSII-1 was introduced into an acrystalliferous of B. thuringiensis both individually and in combination with accessory protein p20 cytolytic cyt1Aa subsp. israelensis. Bioassay results indicated that recombinants B-pMT4(Mtx1) B-pMT9(Mtx1), containing mtx1, had moderate toxicities to binary susceptible resistant Culex quinquefasciatus larvae during vegetative growth stage, but their declined rapidly...