A5071467958- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Blood Coagulation and Thrombosis Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Neonatal Health and Biochemistry
- Pregnancy and preeclampsia studies
- Infant Development and Preterm Care
- Infectious Encephalopathies and Encephalitis
- Cytomegalovirus and herpesvirus research
- Metabolism and Genetic Disorders
- Cystic Fibrosis Research Advances
- Palliative Care and End-of-Life Issues
- Acute Ischemic Stroke Management
- Respiratory viral infections research
- Fetal and Pediatric Neurological Disorders
- Thyroid Disorders and Treatments
- COVID-19 Impact on Reproduction
- Organ Donation and Transplantation
- EEG and Brain-Computer Interfaces
- Thermal Regulation in Medicine
- Global Maternal and Child Health
- Cardiovascular Issues in Pregnancy
Hospital Universitario de Burgos
2016-2025
Fundación Seimc-Gesida
2017-2024
Ibero American University
2024
American Society of Hematology
2023-2024
Ibero-American University Puebla
2024
Universidad de Burgos
2015-2023
Hospital Universitario La Paz
2010-2021
Hospital Universitario de Móstoles
2005-2020
Hospital Clínic de Barcelona
2014
Universidad Autónoma de Madrid
2013
Preliminary data in Europe have suggested a reduction prematurity rates during the COVID-19 pandemic, implying that contingency measures could an impact on rates. We designed population-based prevalence proportion study to explore potential link between national lockdown and change preterm births stillbirths. Adjusted multivariate analyses did not show any decrease proportions period with respect whole prelockdown or comparison periods (2015-2019): 6.5% (95%CI 5.6-7.4), 6.6% 6.5-6.8), 6.2%...
Objective To evaluate the association between neuroimaging and outcome in infants with congenital cytomegalovirus (cCMV), focusing on qualitative MRI quantitative diffusion-weighted imaging of white matter abnormalities (WMAs). Methods Multicentre retrospective cohort study 160 cCMV (103 symptomatic). A four-grade scoring system was applied to cranial ultrasonography acquired at ≤3 months. WMAs were categorised as multifocal or diffuse. Temporal-pole (TPWMAs) consisted swollen cystic...
El neurodesarrollo actual de pacientes con encefalopatía hipóxico-isquémica (EHI) neonatal en España se desconoce. Recientes estudios europeos destacan el desplazamiento la patología grave hacia trastornos motores leves y problemas emocionales. objetivo este estudio fue analizar estado neuroevolutivo integral a los 3 años una cohorte neonatos EHI. Estudio observacional multicéntrico ≥ 35 semanas edad gestacional EHI moderada-grave nacidos entre 2011 2013 12 hospitales extensa región española...
OPINION article Front. Pediatr., 30 April 2020Sec. Neonatology Volume 8 - 2020 | https://doi.org/10.3389/fped.2020.00247
To investigate whether cerebrospinal fluid levels of neuron-specific enolase (CSF-NSE) during the first 72 hours correlate with other tools used to assess ongoing brain damage, including clinical grading hypoxic-ischemic encephalopathy (HIE), abnormal patterns in amplitude integrated electroencephalography (aEEG), and magnetic resonance imaging (MRI), as well neurodevelopmental outcomes at two years age.Prospective observational study performed hospitals between 2009 2011. Forty-three...
<h3>BACKGROUND:</h3> High-flow nasal cannula (HFNC) is increasingly used to provide respiratory support in infants with bronchiolitis. The delivery of aerosol therapy through a jet nebulizer widely indicated despite its controversial efficacy and poor tolerability. <h3>METHODS:</h3> This randomized cross-over study aimed evaluate the comfort satisfaction using nebulization system integrated into HFNC compared standard practice face mask. COMFORT-Behavior (COMFORT-B) scale, visual analog...
<b><i>Introduction:</i></b> There is a paucity of studies examining temporal trends in the incidence and mortality moderate-to-severe hypoxic-ischemic encephalopathy (HIE) during last decade therapeutic hypothermia (TH). <b><i>Methods:</i></b> Multicenter cross-sectional study all infants ≥35 weeks gestational age diagnosed with HIE within 6 h birth an extensive region Spain between 2011 2019, order to detect trend changes over time (1) annual...
In Europe, imported malarial cases occur in returning travelers and immigrants mostly from African countries. There have been an increasing number of the past years Spain. An analysis all malaria who attended at Hospital Mostoles Southwest Madrid 1995 to 2007 was performed. Clinical, epidemiological, laboratory, parasitological findings were analyzed compared between coming endemic countries (recent immigrants) children traveled areas visit friends relatives (VFRs). Sixty detected. Most (59...
Aim To investigate the circumstances surrounding end-of life decisions (EoL) of infants with hypoxic-ischaemic encephalopathy (HIE) and examine changes over a 10-year period. Methods Retrospective chart review all HIE who died during 2000–2004 2005–2009 in Level III Neonatal Intensive Care Unit Madrid, Spain. Results Of 70 HIE, 18 neonatal The mean age death was 64.4 ± 51 h. In 17 (94%), preceded by an EoL decision, four after withholding therapy (WH) 13 withdrawal (WDT). All WH were...
Data on the incidence of hypoxic-ischemic encephalopathy (HIE) in first 6 hours life together with implementation therapeutic hypothermia (TH) are relevant to delineate actions achieve lowest rates neonatal mortality, morbidity, and long-term impact health associated HIE. This is population-based national survey study, including newborns ≥35 weeks gestation moderate-to-severe HIE from all level III care units, provide for period 2012–2013, TH up June 2015 Spain. Incidence rate was 0.77 per...
This document is the result of previous work carried out by different expert groups and submitted to multidisciplinary debate at a Conference about controversial, deficient, or new aspects in field neonatal palliative care, such as: 1) deliberative decision-making process, 2) hospital domiciliary 3) donation after controlled cardiac death, 4) moral stress professionals. The most relevant conclusions were: need instruct professionals bioethics method facilitate thorough reasonable...
Cerebral oximetry using near-infrared spectroscopy (NIRS) provides continuous, noninvasive assessment of the degree hemoglobin saturation brain tissue. Previous studies suggest that high values regional cerebral tissue oxygen (rScO2) during first days in neonates with significant hypoxic-ischemic encephalopathy (HIE) are correlated an adverse neurological outcome. However, results not consistent among studies. To examine correlation rScO2 and their variability over time HIE severity,...
The current neurodevelopmental status of patients with neonatal hypoxic-ischaemic encephalopathy (HIE) in Spain is unknown. Recent European studies highlight a shift severe pathology towards mild motor disorders and emotional problems. aim this study was to analyse outcomes cohort neonates HIE at age 3 years. Multicentre observational born 35 or more weeks gestation moderate 2011–2013 12 hospitals large Spanish region (91 217 m2), the recruitment extended through 2017 coordinating hospital....
Se estima que el 96% de los recién nacidos (RN) con encefalopatía hipóxico-isquémica (EHI) nacen en entornos recursos limitados (ERL) sin capacidad para ofrecer estándar asistencial vigente desde hace cerca 15 años países altos y incluye hipotermia terapéutica, neuromonitorización continua electroencefalográfica resonancia magnética, además un control intensivo las constantes vitales del equilibrio homeostático. Esta situación no parece estar cambiando; embargo aún estas limitaciones,...
Programs that aim to improve the detection hypoxic-ischemic encephalopathy (HIE) should establish which neonates suffering from perinatal asphyxia need be monitored within first 6 h of life.
There are no data on the incidence of hypoxic-ischaemic encephalopathy (HIE) and implementation therapeutic hypothermia (TH) in Spain.This is a cross-sectional, national study, performed using an on-line questionnaire targeting level III neonatal care units Spain. Participants were requested to provide all newborns ≥ 35 weeks gestational age diagnosed with moderate-severe HIE over two year-period (2012-2013), TH up June 2015.All (90) contacted hospitals participated. rate was 0.77/1000 live...