A5103185490- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Glaucoma and retinal disorders
- Information and Cyber Security
- Lipoproteins and Cardiovascular Health
- Risk and Safety Analysis
- Adversarial Robustness in Machine Learning
- Heart Failure Treatment and Management
- Airway Management and Intubation Techniques
- Retinal and Optic Conditions
Belfast Health and Social Care Trust
2022
Royal Victoria Hospital
2016-2020
University of Ulster
2016-2020
Royal Victoria Hospital
2012
One of the few interventions to demonstrate improved outcomes for acute hypoxaemic respiratory failure is reducing tidal volumes when using mechanical ventilation, often termed lung protective ventilation. Veno-venous extracorporeal carbon dioxide removal (vv-ECCO2R) can facilitate volumes. pRotective vEntilation with veno-venouS assisT (REST) a randomised, allocation concealed, controlled, open, multicentre pragmatic trial determine clinical and cost-effectiveness lower volume ventilation...
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure. There are in vitro, animal studies pre-clinical data suggesting that statins may be beneficial ALI. The Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin to Reduce Pulmonary dysfunction (HARP-2) trial multicenter, prospective, randomized, allocation concealed, double-blind, placebo-controlled which...
Evaluating the effects of cibinetide in diabetic macular edema (DME).Phase 2 trial. Naïve patients with >400 µm central retinal thickness (CRT) DME one/both eyes were recruited (May 2016-April 2017) at Belfast Health and Social Care Trust. The study eye was that best vision lowest CRT. Patients self-administered 4 mg/day subcutaneously for 12 weeks. Primary secondary outcomes: mean change from baseline to week corrected visual acuity (BCVA), CRT, sensitivity, tear production,...
Background Acute lung injury is a common devastating clinical syndrome characterised by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure, major cause of morbidity mortality. Objective This study tested the hypothesis that treatment with simvastatin would improve outcomes in patients acute distress (ARDS). Design was multicentre, allocation-concealed, randomised, double-blind, parallel-group trial. Setting/participants Patients intensive care...
Introduction Diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) are the major causes of sight loss in people with diabetes. Due to increased prevalence diabetes, workload related these complications is increasing making it difficult for Hospital Eye Services (HSE) meet demands. Methods analysis Effectiveness Multimodal imaging Evaluation Retinal And new vesseLs (EMERALD) a prospective, case-referent, cross-sectional diagnostic study. It aims at determining...
To explore acceptability by patients and health care professionals of a new surveillance pathway for people with previously treated stable diabetic macular oedema (DMO) and/or proliferative retinopathy (PDR).Structured discussions in 10 focus groups patients; two ophthalmic photographers/graders, one ophthalmologists, held across the UK as part large diagnostic accuracy study (EMERALD).The most prominent issues raised concerned (i) expertise various within clinic, (ii) quality interactions...