A5100445120- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Supramolecular Chemistry and Complexes
- Mass Spectrometry Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Petroleum Processing and Analysis
- Hydrogels: synthesis, properties, applications
- DNA and Nucleic Acid Chemistry
- Photoreceptor and optogenetics research
- Block Copolymer Self-Assembly
- Surfactants and Colloidal Systems
- Advanced Nanomaterials in Catalysis
- Analytical Chemistry and Chromatography
- Lanthanide and Transition Metal Complexes
- Amino Acid Enzymes and Metabolism
- Analytical Chemistry and Sensors
- Metabolomics and Mass Spectrometry Studies
- Advanced Polymer Synthesis and Characterization
- Enhanced Oil Recovery Techniques
- Nanoplatforms for cancer theranostics
- Photochromic and Fluorescence Chemistry
Guilin University of Technology
2022
Jiangsu University
2014-2022
Peking Union Medical College Hospital
2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Shanghai Medical College of Fudan University
2021
Fudan University Shanghai Cancer Center
2021
Jiangnan University
2011-2012
National Taiwan University
2001-2007
Accurate diagnosis and therapy are challenging because most diseases lack a single biomarker that distinguishes them from other disorders. A solution would enhance targeting accuracy by using AND-gated combinations of two disease-associated stimuli. Here, we report novel "AND" molecular logic gate, enabling double-controlled release intact functional molecules. Benefiting significant difference in intramolecular cyclization rate, cargo occurs notably faster with the presence both According...
Zeolitic imidazolate framework-8 (ZIF-8) has been successfully employed as a protective coating to encapsulate enzyme via various immobilization strategies by recent works. However, in all of the research, ZIF-8 only acts enzyme-immobilization matrix. In this work, exploiting fluorescence quenching properties surface, we for first time properly amalgamated basic functionalities horseradish peroxidise (HRP) encapsulation and quencher constructing HRP@ZIF-8/DNA hybrids gave successive...
We describe a [2]rotaxane molecule that exhibits distinct signals in its 1H NMR spectra upon the complexation of physiologically important Li+, Na+, Mg2+ and Ca2+ ions; thus, identification these metal ions solution is possible from analysis single spectrum molecular sensor.
Going beyond organic solvent as the solubilizer for small-molecular probes motivates exploration of water-soluble polymeric sensors. In this respect, dye-derived thermal-responsive sensors are an attractive direction, but its practical application, it is limited by sensor recycling because only irreversible change in structure recognition unit many can trigger appearance detection signal. Here, we established oligonucleotide-derived sensor, TBC-P1, which overcame fundamental limitation. The...
Hydrogen bonding interactions were intensified in the present study by adjusting chain architectures, which provided a sufficient driving force for UCST phase transition pure water.
Ureyleno crown ethers 2 and 3 bind with equiv of Li+ cooperatively selectively over other alkali metal ions such as Na+, K+, Cs+. The binding constant for was found to be 3.0 × 107 (L/mol)2.
Tris(2-((pyrid-2-ylmethyl)uredio)ethyl)amine (2) and its perchlorate salt, 2.HClO(4), bind with Li+ in nitromethane a 1:1 fashion. The stability constants of K(Li+) K(H)(Li+) were found to be 112 +/- 25 130 30 M(-)(1) CD(3)NO(2), respectively. Formation the complexes further evidenced by electrospray ionization mass spectrometry (ESI-MS). slight increase, or at least same order magnitude, compared points remarkable preorganization protonated podand that essentially overcomes increased...
Based on the determination of equilibrium surface tension for anionic surfactant SDS and non-ionic TrionX-100 under different concentrations, two surfactants continuous boiling test hydrolysis tests were carried out. Objective is to analyze diminishing process active ingredient surfactants. Results show that liquid with capable reducing tension. With increment concentration, decreases gradually, minimized critical micelle concentration (CMC); When lower than CMC, surface-active TritonX-100...
Abstract Clomiphene, trimetazidine, and meldonium are three common clinical drugs, long-term consumption will cause damage to human health. Currently, animal-derived food contamination is a major concern, these compounds have high probability of entering the body remaining there for long time. In this study, liquid chromatography-tandem triple quadrupole mass spectrometry method was developed determine residues metabolic regulators in food. With 0.1% formic acid water-acetonitrile solution...