Ulcerative colitis (UC) is an inflammatory disease that affects the colon and rectum. Recently, evidence has emerged about influence of microbiota on development this disease. However, studies role intestinal in pathogenesis UC have been incomplete. In addition, there are no comprehensive causes ulcerative data microbiological composition intestines patients with Russia. We carried out a study healthy individuals. found significant changes bacteria genera species compared control group using...

Probiotics are living microorganisms that provide numerous health benefits for their host. have various effects on the body; example, they change gut microbiota, improve integrity of epithelial barrier and anti-inflammatory effects. The use probiotic supplements based lactic acid bacteria bifidobacteria is one approaches used to balance microflora. In our study, we evaluated supplements, which were members Lactobacillaceae family bifidobacteria, microbiome healthy mice using 16S rRNA...

Obesity is a problem of modern health care that causes the occurrence many concomitant diseases: arterial hypertension, diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular diseases. New strategies for treatment prevention obesity are being developed based on using probiotics modulation gut microbiota. Our study aimed to evaluate bacterial composition obese patients before after two weeks lactic acid bacteria (

In recent decades an increase in the use of pesticides to protect plants from pests, diseases and weeds has been observed. There are many studies on effects various non-target organisms. This review aims analyze summarize published scientific data animal microbiome. Pesticides can affect parameters microbiome, such as taxonomic composition bacteria, bacterial biodiversity, ratios modify microbiome organisms insects mammals. Pesticide induced changes reducing animal’s immunity. The negative...

Determining the taxonomic composition of microbial consortia piglet intestine is great importance for pig production. However, knowledge on variety intestinal microbiome in newborn piglets limited. Piglet diarrhea a serious gastrointestinal disease with high morbidity and mortality that causes economic damage to industry. In this study, we investigated various sections compared healthy diarrheal using high-throughput sequencing 16S rRNA gene. The results showed bacteria Lactobacillus genus...

Irritable bowel syndrome (IBS) is a common condition that affects the lifestyle of patients. It associated with significant changes in composition gut microbiome, but underlying microbial mechanisms remain to be fully understood. We study fecal microbiome patients constipation-predominant IBS (IBS-C) and mixed-type (IBS-M).

The role of lipopolysaccharide (LPS) in the development diseases is clear, but specific mechanisms remain poorly understood. This study aimed to investigate microbiome aberrations guts mice against background LPS, as well anti-inflammatory effect probiotic supplementation with Lactobacillus plantarum from gut, a mix commercial lactic acid bacteria, and Weissella confusa isolated milk using next-generation sequencing. LPS injections were found induce inflammatory changes intestinal mucosa....

In recent years, the number of pollinators in world has significantly decreased. A possible reason for this is toxic effects agrochemicals reducing immunity insects that leads to their increased susceptibility pathogens. Ascosphaera apis a dangerous entomopathogenic fungus, afflicting both honeybees and bumblebees. We investigated fungicide activity cyclic synthetic peroxides against A. isolated from Bombus terrestris L. The exhibited high mycelium growth inhibition up 94–100% at...

Plant mitochondrial respiration involves the operation of various alternative pathways. These pathways participate, both directly and indirectly, in maintenance functions though they do not contribute to energy production, being uncoupled from generation an electrochemical gradient across membrane thus ATP production. Recent findings suggest that is involved reactive oxygen species (ROS) nitric oxide (NO) scavenging, regulation, homeostasis. Here we discuss specific roles possible ROS NO...

Mastitis is the most common disease for cattle, causing great economic losses global dairy industry. Recent studies indicate multi-agent and microbiome diversity of this disease. To understand nature mastitis investigate role in development pathologies udder bovines, we performed NGS sequencing 16S rRNA gene cow’s milk with udder. The obtained data show a significant increase Cutibacterium, Blautia, Clostridium sensu stricto 2, Staphylococcus, Streptococcus Microbacterium genera groups cows...

Emerging evidence suggests that the reproductive tract microbiota is a key modulator of local inflammatory and immune pathways throughout pregnancy may subsequently impact outcomes. In this study, our objective was to analyze cervical vaginal microbiomes during early among three groups: women with healthy ongoing pregnancies, undergoing dydrogesterone treatment, those who experienced miscarriages. The experiment involved 51 at 8–11 weeks gestation. microbiome examined using 16S rRNA...

Endometritis is one of the most frequently detected diseases cattle, which associated with disturbances in microbial balance uterine cavity. This pathological process leads to animal fertility, and, consequently, economic losses dairy industry. In this regard, it important carry out timely preventive measures and have effective drugs for treatment postpartum endometritis. The aim study was evaluate effect based on bovine recombinant interferon "Biferon-B" "EnrofloxacinferonB" taxonomic...

Impaired fertility in cattle is the cause of economic losses livestock farms. Complex treatment cows with acute endometritis may include various approaches, including use antibiotics and interferon-based drugs. The therapeutic approach associated immunostimulating substances safest. aim study was to evaluate blood parameters during postpartum catarrhal using «Enrofloxacinferon-B» «GentabiferonB». It found that therapy «Enrofloxacinferon-B», «Gentabiferon-B», traditional regimen led an...

Systemic lipopolysaccharide (LPS)-induced inflammation has a significant impact on various organs, including the male reproductive system. In this study, we have demonstrated that LPS-induced causes oxidative stress in mouse testes, reduces expression of genes encoding catalytic subunit glutamate-cysteine ligase (Gclc) and superoxide dismutase 2 (Sod2). Inflammation suppressed transcription involved differentiation metabolic regulation testicular cells sperm maturation: LPS group, Amh, Lepr,...

Mastitis is recognized as the most common disease in cattle and causes economic losses dairy industry. A number of opportunistic bacterial taxa have been identified causative agents for this disease. Conventionally, antibiotics are used to treat mastitis; however, bacteria resistant majority antibiotics. This study aimed use molecular methods identify milk microbiome patterns characteristic mastitis that can help early diagnosis development new treatment strategies. To evaluate composition,...

Beverages are an integral component of a person’s food package. Various types microorganisms widely contaminate beverages. This review presents current research data aimed at identifying dominant in beverages and molecular methods for their detection. Wine, beer, dairy drinks, fruit juices were selected as the main objects study. The most contaminated beverage turned out to be juice. As result large number independent studies, about 23 species identified it. At same time, they represented...