This work reports the reinforcement of poly(vinyl alcohol) (PVA) hydrogel with halloysite nanotubes (HNT) as potential biomedical materials. The nanocomposite was prepared using facile and harmless process freeze–thawing. Mechanical properties hydrogels were optimum at 2 wt% HNT loading. Morphological topographic analysis PVA/HNT revealed excellent filler dispersion smoothing surface due to good compatibility between components. Immersion in simulated body fluid for 7 days resulted formation...

The aim of this study is to prepare a dual layer polyvinyl (PVA) patch using combination electrospinning techniques and cryogelation (freeze-thaw process) then subsequently investigate the effect freeze-thaw cycles, nanofiber thickness, diclofenac sodium (DS) loading on physicochemical mechanical properties formulation PVA patches composed electrospun nanofibers cryogel. After successful preparation patch, prepared was subjected investigation assess thickness percentages DS morphology,...

This work reports the surface modification of 3D printed PLA scaffold with chitosan and its hydroxyapatite (HA) forming capability. was fabricated using a desktop printer followed by inclusion on via entrapment. Confocal laser scanning microscopy (CLSM) images showed existence entrapment depth 24 μm. Immersion modified in simulated body fluid resulted formation apatite layers surface. Plus method does not induce any cytotoxic response towards human fibroblast cell. provides facile approach...

Abstract Implantable drug delivery systems (IDDSs) play a vital role in treating chronic diseases by reducing dosing frequency and enhancing efficacy due to targeted delivery. In the present study, an IDDS was developed from electrospun cellulose acetate (CA) polycaprolactone (PCL) nanofiber membranes. The implant core consists of drug‐loaded CA (CA + Vit.D 3 ) enclosed rate limiting PCL membrane /PCL). nanofibrous membranes were characterized using scanning electron microscope (SEM),...

Nerve tissue engineering requires biomaterials that provide mechanical strength, biocompatibility, and an optimal microenvironment for cell attachment proliferation. Electrospun polymeric scaffolds have gained attention due to their structural similarity the extracellular matrix. However, inherent brittleness limited bioactivity necessitate further enhancement. This study investigates effects of incorporating a polyvinyl alcohol/collagen/halloysite nanotube (PVA/Col/HNT) hydrogel on...

This paper reports the preliminary study about incorporation of halloysite nanotubes (HNT) into polylactic acid (PLA) scaffold to improve thermal resistance and surface wettability properties. The fabrication porous requires a simple yet effective technique with low-cost materials within freeze extraction method. stability PLA/HNT compared neat PLA achieved increased content HNT by 5 wt%. Moreover, also shows positive impact high new nanocomposite may have potential as suitable template for...

Transdermal drug delivery systems (TDDS) have drawn more interest from pharmaceutical scientists because they could provide steady blood levels and prevent the first-pass metabolism over a longer period. Polyvinyl alcohol (PVA) has been widely used in this application due to its biocompatibility, non-toxicity, nanofiber hydrogel-forming ability. Despite those benefits, their morphology would easily be destroyed by continuous water absorption contribute burst release hydrophilicity. The aim...

Novel conducting kenaf core/polyaniline (KC-PANI) biofibers were successfully prepared via in situ oxidative polymerization. The newly developed KC achieved enhancement DC conductivity up to seven fold compared the raw KC. Enhanced interaction was obtained between acetylated KC-PANI surfaces untreated KC-PANI, without significant loss cellulose crystallinity. morphological analysis revealed uniform layers of PANI deposited on surface Epoxy resin (EP) containing (EP/KC-PANI composites) showed...

Purpose Over the years, electrical stimulation in drug delivery system holds particular interest producing spatially and temporally controlled release mechanism. These systems helped localized doses drugs to be administrated response efficiently at target site achieve excellent healing effect control microenvironment. Extensive research is needed order develop versatile electroactive biomaterials field of therapeutics applications. This paper aims discuss this issue....

Bacterial cellulose (BC) is an innovative polymeric nanofibre, which meets the demands of rapidly advancing industries, such as biomedical engineering, food packaging, pulp and paper electrical appliance engineering.The versatility bacterial largely due to its unique properties, high crystallinity, thermal stability, water absorption capacity, hydrophilicity, good mechanical strength, biodegradability, biocompatibility porosity, making it well-suited for applications in various fields.In...

This work reports the modification of freeze/thaw poly(vinyl alcohol) hydrogel using citric acid as bioactive molecule for hydroxyapatite formation in simulated body fluid. Inclusion 1.3 mM into showed that mechanical strength, crystalline phase, functional groups and swelling ability were still intact. Adding at higher concentrations (1.8 2.3 mM), however, resulted physically poor hydrogels. Presence growth porous crystals on surface just after one day immersion Meanwhile, a fully covered...

This work reports the reinforcement of polyvinyl alcohol (PVA) hydrogel with chitosan as potential superabsorbent (SAP) fertilizer.The PVA/Chitosan was prepared using superficial freeze thawing method.Mechanical properties and swelling ratio SAP hydrogels were optimum at 6 wt% loading.Morphological analysis revealed excellent crystal like structure distribution smooth surface due to good compatibility between materials.The water retention soil containing also examined.It found that increased...

Newly developed packaging paper made of biopulped pineapple leaf fiber (PALF) and poly(lactic acid)(PLA) was studied. PALF sheets were solvent impregnated with PLA at different concentrations in order to improve their moisture barrier mechanical performance. With the impregnation a concentration 4%, material exhibited low uptake high tear index. An electron micrograph sample 4% revealed uniform packed reversed microsphere morphology. These results suggest that surface coating via...