A5030776837- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Enzyme Catalysis and Immobilization
- Pancreatic function and diabetes
- biodegradable polymer synthesis and properties
- Polyamine Metabolism and Applications
- Aquaculture Nutrition and Growth
- Polysaccharides and Plant Cell Walls
- Tissue Engineering and Regenerative Medicine
- GABA and Rice Research
- Microencapsulation and Drying Processes
- Algal biology and biofuel production
- Photosynthetic Processes and Mechanisms
- Catalysis for Biomass Conversion
- Aquatic life and conservation
- Selenium in Biological Systems
- Liver physiology and pathology
- Neurobiology and Insect Physiology Research
- Neurological disorders and treatments
- Scoliosis diagnosis and treatment
- Mercury impact and mitigation studies
- Physiological and biochemical adaptations
- Hereditary Neurological Disorders
- Ferroelectric and Negative Capacitance Devices
- Celiac Disease Research and Management
Xiangtan University
2024
Shantou University
2008-2023
Shandong Xiehe University
2021
Shandong University
2021
The University of Queensland
2021
Xinqiao Hospital
2019
Affiliated Hospital of Chengde Medical College
2017
Chinese Academy of Sciences
2006-2016
Qingdao Institute of Bioenergy and Bioprocess Technology
2015-2016
Tianjin Medical University General Hospital
2011
Abstract Succinic acid (SA) is an important C4-dicarboxylic acid. Microbial production of SA at low pH results in purification costs and hence good overall process economics. However, redox imbalances limited biosynthesis from glucose via the reductive tricarboxylic (TCA) cycle yeast. Here, we engineer strictly aerobic yeast Yarrowia lipolytica for efficient without control. Introduction TCA into cytosol a succinate dehydrogenase-disrupted strain causes arrested cell growth. Although...
HfO2-based ferroelectric field-effect transistors (FeFETs) are regarded as one of the most promising non-volatile memory technologies in future. However, charge trapping phenomenon during program/erase operation is still a challenge. In this work, we comprehensively investigate behaviors semiconductor/insulator interface FeFETs. Through analyzing effects spatial distribution traps and polarization switching speed, coupling recognized. We also find that band tail state have much less...
The main methods of crime governance are pre prevention and post crackdown. With the development intelligence information technology, public security work has also ushered in new opportunities challenges. This paper used intelligent algorithms combines characteristics with existing big data resources system to propose a multidimensional facial recognition model based on TF-IDF algorithm, it warning BP neural network form closed chain investigation. dual guarantee is great significance...
Abstract Background Natural glycolysis encounters the decarboxylation of glucose partial oxidation product pyruvate into acetyl-CoA, where one-third carbon is lost at CO 2 . We previously constructed a saving pathway, EP-bifido pathway by combining Embden-Meyerhof-Parnas Pathway, Pentose Phosphate Pathway and “bifid shunt”, to generate high yield acetyl-CoA from glucose. However, conversion rate reducing power this was not optimal, flux ratio EMP pentose phosphate (PPP) needs be precisely...
As the greenhouse effect becomes more serious and carbon dioxide emissions continue rise, application prospects of sequestration or carbon-saving pathways increase. Previously, we constructed an EP-bifido pathway in Escherichia coli by combining Embden-Meyerhof-Parnas pathway, pentose phosphate "bifid shunt" for high acetyl-CoA production. There is much room improvement including production target compounds such as poly(hydroxybutyrate) (PHB).To optimize obtain higher PHB yields, knocked out...
Abstract Microencapsulation of recombinant cells is a novel means for gene therapy. However, one the major concerns relationship between permeability microcapsule and cell growth. Many studies have focused on empty microcapsule, but little known about effect growth cell‐contained microcapsule. A combination fluorescence labeled protein confocal laser scanning microscope (CLSM) provides information changes during decrease membrane was detected 14th day. Meanwhile, surface fouling also...
As a category A toxic, the botulinum toxin(BoNT) is responsible for human botulism with an estimated lethal dose of 1 ng/kg which greatly increases potential risk use as bioweapons. Therefore, development anti-BoNT antibodies urgent. In this paper, HC domain BoNT/A was purified and immunized Balb/c mice. Monoclonal were screened against from 55 stable positive hybridoma cell lines, one strongest neutralizing activity, designated ML06, subcloned, sequenced, classified IgG1(κ) subclass. The...