Michael Friedmann

ORCID: 0000-0001-9109-4003
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Optical measurement and interference techniques
  • Banana Cultivation and Research
  • Plant Virus Research Studies
  • Climate change impacts on agriculture
  • Insect-Plant Interactions and Control
  • Genetic and phenotypic traits in livestock
  • Immune Cell Function and Interaction
  • Electric and Hybrid Vehicle Technologies
  • Advanced Measurement and Metrology Techniques
  • Advanced Optical Sensing Technologies
  • Plant Gene Expression Analysis
  • Cytokine Signaling Pathways and Interactions
  • Vehicle Dynamics and Control Systems
  • Genetics and Plant Breeding
  • Agricultural Innovations and Practices
  • Vehicle emissions and performance
  • Immune Response and Inflammation
  • Plant biochemistry and biosynthesis
  • Optical Coherence Tomography Applications
  • Surface Roughness and Optical Measurements
  • Plant Pathogens and Resistance
  • Advanced Combustion Engine Technologies
  • Plant Molecular Biology Research
  • Bioenergy crop production and management

International Potato Center
2017-2024

Impact
2024

Impact Technology Development (United States)
2024

Bioversity International
2021

Ithaca College
2021

University of Koblenz and Landau
2017-2021

CGIAR
2019-2021

Technische Universität Ilmenau
2019

Fraunhofer Institute for Chemical Technology
2015

Fraunhofer Society
2015

Interleukin-2 (IL-2) signaling requires the dimerization of IL-2 receptor β (IL-2Rβ) and common γ (γ c ) chains. Mutations can result in X-linked severe combined immunodeficiency (XSCID). IL-2, IL-4, IL-7 (whose receptors are known to contain ), IL-9 is shown here induced tyrosine phosphorylation activation Janus family kinases Jak1 Jak3. Jak3 associated with IL-2Rβ , respectively; Jak3-IL-2Rβ increased Jak3-γ associations. Truncations a point mutation causing moderate (XCID), decreased...

10.1126/science.7973658 article EN Science 1994-11-11

The interleukin-2 (IL-2) receptor γ chain (IL-2Rγ) is an essential component of high- and intermediate-affinity IL-2 receptors. IL-2Rγ was demonstrated to be a the IL-4 on basis chemical cross-linking data, ability augment binding affinity, requirement for in IL-4-mediated phosphorylation insulin substrate-1. observation that functional receptor, together with finding associates IL-7 begins elucidate why deficiency this common (gamma; c ) has profound effect lymphoid function development, as...

10.1126/science.8266078 article EN Science 1993-12-17

Summary P opulus trichocarpa is widespread across western North America spanning extensive variation in photoperiod, growing season and climate. We investigated trait . using over 2000 trees from a common garden at V ancouver, C anada, representing replicate plantings of 461 genotypes originating 136 provenance localities. measured 40 traits encompassing phenological events, biomass accumulation, growth rates, leaf, isotope gas exchange‐based ecophysiology traits. With replicated 29 354...

10.1111/nph.12601 article EN New Phytologist 2013-11-25

ABSTRACT Conifers are resistant to attack from a large number of potential herbivores or pathogens. Previous molecular and biochemical characterization selected conifer defence systems support model multigenic, constitutive induced defences that act on invading insects via physical, chemical, ecological (multitrophic) mechanisms. However, the genomic foundation complex resistance mechanisms conifers is largely unknown. As part genomics strategy characterize inducible possible against insect...

10.1111/j.1365-3040.2006.01532.x article EN public-domain Plant Cell & Environment 2006-06-06

Summary Geminiviruses comprise a large and diverse family of viruses that infect wide range important monocotyledonous dicotyledonous crop species cause significant yield losses. The Geminiviridae is divided into three genera, one which Begomovirus . Species this genus are transmitted by the whitefly Bemisia tabaci in persistent, circulative manner plants. Severe population outbreaks B. usually accompanied high incidence begomoviruses. During last two decades, there has been worldwide spread...

10.1111/j.1744-7348.2002.tb00163.x article EN Annals of Applied Biology 2002-04-01

One of the earliest events induced by interleukin 2 (IL-2) is tyrosine phosphorylation cellular proteins, including IL-2 receptor beta chain (IL-2Rbeta). Simultaneous mutation three tyrosines (Y338, Y392, and Y510) in IL-2Rbeta cytoplasmic domain abrogated IL-2-induced proliferation, whereas only Y338 or Y392 Y510 inhibited proliferation partially. While were critical for activation signal transducers activators transcription (STAT proteins), was required Shc-IL-2Rbeta association Shc. Thus,...

10.1073/pnas.93.5.2077 article EN Proceedings of the National Academy of Sciences 1996-03-05

Summary In order to uncover the genetic basis of phenotypic trait variation, we used 448 unrelated wild accessions black cottonwood ( Populus trichocarpa ) from much its range in western North America. Extensive data large‐scale phenotyping (with spatial and temporal replications within a common garden) genotyping 34 K single nucleotide polymorphism SNP array) all were for gene discovery genome‐wide association study GWAS ). We performed with 40 biomass, ecophysiology phenology traits 29 355...

10.1111/nph.12815 article EN New Phytologist 2014-04-22

Abstract The highly resistant biopolymer, sporopollenin, gives the outer wall (exine) of spores and pollen grains their unparalleled strength, shielding these structures from terrestrial stresses. Despite a limited understanding composition it appears that synthesis sporopollenin occurs in tapetum requires transport one or more constituents to surface developing microspores. Here, we describe ABCG26, member ATP-binding cassette (ABC) transporter superfamily, which is required for exine...

10.1104/pp.110.161968 article EN cc-by PLANT PHYSIOLOGY 2010-08-23

The completion of the Populus trichocarpa (Torr. & A. Gray) (poplar) genome sequence offers an opportunity to study complete families in a third fully sequenced angiosperm (after Arabidopsis and rice) conduct comparative genomics studies gene family evolution. We focussed on encoding phenylpropanoid phenylpropanoid-like enzymes, identified annotated full set genes these related enzymes poplar genome. used similar approach identify analogous from rice generated phylogenetic trees for nine...

10.1139/b07-098 article EN Canadian Journal of Botany 2007-12-01

Summary Establishing links between phenotypes and molecular variants is of central importance to accelerate genetic improvement economically important plant species. Our work represents the first genome‐wide association study inherently complex currently poorly understood architecture industrially relevant wood traits. Here, we employed an Illumina Infinium 34 K single nucleotide polymorphism ( SNP ) genotyping array that generated 29 233 high‐quality s in c . 3500 broad‐based candidate...

10.1111/nph.12422 article EN New Phytologist 2013-07-26

Climate-smart agriculture (CSA) is widely promoted as an approach for reorienting agricultural development under the realities of climate change. Prioritising research-for-development activities crucial, given need to utilise scarce resources effectively possible. However, no framework exists assessing and comparing different CSA research investments. Several aspects make it challenging prioritise research, including its multi-dimensional nature (productivity, adaptation mitigation),...

10.1016/j.agsy.2018.09.009 article EN cc-by-nc-nd Agricultural Systems 2018-10-05

The 2015 ACM Recommender Systems Challenge offered the opportunity to work on a large-scale e-commerce dataset from big retailer in Europe which is accepting recommender system as service YOOCHOOSE. Participants tackled problem of predicting what items user intends purchase, if any, given click sequence performed during an activity session website. challenge ran for seven months and was very successful, attracting 850 teams 49 countries submitted total 5,437 solutions. winners scored...

10.1145/2792838.2798723 article EN 2015-09-16

The effect of tomato yellow leaf curl virus (TYLCV) on total yield and components various resistant F1 cultivars new breeding lines was evaluated in the field. Seeds hybrids 8484, 3761, Fiona, Tyking TY172 TY197 were sown an insect-proof greenhouse. When seedlings reached first-leaf stage, they inoculated with TYLCV by means whitefly vector Bemisia tabaci. Noninoculated plants same cultivar or line which exposed to nonviruliferous whiteflies served as controls. After a short recovery period,...

10.1094/pdis.1997.81.12.1425 article EN other-oa Plant Disease 1997-12-01

Tomato yellow leaf curl virus (TYLCV), transmitted by the tobacco whitefy ( Bemisia tabaci Genn.), can be devastating to tomato Lycopersicon esculentum L.) crops in tropical and subtropical regions. The development of resistant cultivars is best option for control TYLCV. However, all available commercial tested at Volcani Center, when inoculated with TYLCV, developed different levels disease symptoms. In this study, we report a breeding line, TY172, which symptomless carrier Line whether...

10.21273/jashs.123.6.1004 article EN Journal of the American Society for Horticultural Science 1998-11-01

Abstract Genetic mapping of quantitative traits requires genotypic data for large numbers markers in many individuals. For such studies, the use single nucleotide polymorphism ( SNP ) genotyping arrays still offers most cost‐effective solution. Herein we report on design and performance a array Populus trichocarpa (black cottonwood). This was designed with s pre‐ascertained 34 wild accessions covering species latitudinal range. We adopted candidate gene approach to that resulted selection...

10.1111/1755-0998.12056 article EN Molecular Ecology Resources 2013-01-11

The effect that Tomato yellow leaf curl virus (TYLCV)-infected resistant tomato plants may have on epidemiology was studied. Four genotypes exhibit different levels of viral resistance, ranging from fully susceptible to highly resistant, served as TYLCV-infected source plants. Viral acquisition and transmission rates by white-flies following feeding the were evaluated. TYLCV rate whiteflies had fed infected 21 days postinoculation (DPI), shortly after appearance symptoms, negatively...

10.1094/phyto.2001.91.12.1209 article EN other-oa Phytopathology 2001-12-01

Abstract The CGIAR Research Program (CRP) on Roots, Tubers and Bananas (RTB) includes vegetatively propagated staple crops linked by common breeding, seed, postharvest issues, the frequency with which women are involved in their production use. RTB backbone of food security across humid tropics sub-Saharan Africa (SSA) more localized areas Asia Latin America. Around 300 million poor people developing countries currently depend value chains for security, nutrition income. Climate change poses...

10.1515/opag-2017-0039 article EN cc-by Open Agriculture 2017-02-23

Climate change is projected to negatively impact food systems in Sub-Saharan Africa. The magnitude of these impacts expected be amplified by the extensive reliance on rainfed agriculture and prevalence subsistence farming. In Great Lakes Region Central Africa, smallholder farming households are largely dependent root, tuber banana crops. However, potential various climate scenarios crops not well reported. Yet, data-rich insights about future adaptive capacity critical inform research...

10.1016/j.agsy.2021.103246 article EN cc-by-nc-nd Agricultural Systems 2021-08-14

Plant yield is the integrated outcome of processes taking place above and below ground. To explore genetic, environmental developmental aspects fruit in tomato, we phenotyped an introgression line (IL) population derived from a cross between cultivated tomato (Solanum lycopersicum) wild species pennellii). Both homozygous heterozygous ILs were grown irrigated non-irrigated fields evaluated for six components. Thirteen lines displayed transgressive segregation that increased agronomic...

10.1007/s00122-010-1456-9 article EN cc-by-nc Theoretical and Applied Genetics 2010-09-25
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