A5011072398- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Immune responses and vaccinations
- Cardiovascular Function and Risk Factors
- Immune cells in cancer
- Computational Drug Discovery Methods
- Cardiac Fibrosis and Remodeling
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Tissue Engineering and Regenerative Medicine
Zhongda Hospital Southeast University
2020-2024
Atherosclerotic disease is a substantial global burden, and existing treatments, such as statins, are recommended to lower low-density lipoprotein cholesterol (LDL-C) levels inhibit the progression of atherosclerosis. However, side effects, including gastrointestinal unease, potential harm liver, discomfort in muscles, might be observed. In this study, we propose novel method using periodic mesoporous silica nanoparticles (PMS) create heparin-modified PMS (PMS-HP) with excellent...
Ly6Chigh monocytes are inflammatory cells that accumulate in an infarcted myocardium, and Ly6Clow believed to be reparative curb myocardial remodeling. NR4A1 is a novel target for modulating the phenotype of during atherogenesis. We aimed investigate whether MSCs can contribute heterogeneity differentiated into this regulation related nuclear receptor NR4A1. Ly6Chigh/low were first cocultured with MSCs. C57BL/6CX3CR1-/- mice C57BL/6 wild-type then used construct AMI models, survival...
Quantitative flow ratio (QFR) is a new method for the assessment of extent coronary artery stenosis. But it may be obscured by cardiac remodeling and abnormal blood when encountering atrial fibrillation (AF). The present study aimed to examine impact these changed structures arteries on QFR results in AF patients. Methods Results. We evaluated 223 patients (112 with AF; 111 non-AF served as controls) who had undergone percutaneous intervention (PCI) due severe stenoses arteries. target was...
Abstract Quantitative Flow Ratio (QFR) is now a new method for the assessment of extent coronary artery stenosis but may be obscured by involvement mutated status anatomical structure and blood flow in when encountering Atrial Fibrillation (AF). In this study, we aimed to expose effect on QFR results AF patients. Methods results: We evaluated 223 patients (112 with AF; 111non-AF served as control) who had undergone PCI-ES due severe stenoses arteries. target was determined according rate...