A5008429809- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Chromatin Remodeling and Cancer
- Medical Imaging Techniques and Applications
- Spine and Intervertebral Disc Pathology
- Cancer Mechanisms and Therapy
- Neuroendocrine Tumor Research Advances
- Osteoarthritis Treatment and Mechanisms
- Advanced Radiotherapy Techniques
- Advanced Neuroimaging Techniques and Applications
- Cervical and Thoracic Myelopathy
- Amyotrophic Lateral Sclerosis Research
- Radiopharmaceutical Chemistry and Applications
- Coronary Artery Anomalies
- Cancer Treatment and Pharmacology
- Neonatal and fetal brain pathology
- Neuroblastoma Research and Treatments
- Head and Neck Cancer Studies
- Vasculitis and related conditions
- Rheumatoid Arthritis Research and Therapies
- Vascular Malformations Diagnosis and Treatment
- Cerebral Palsy and Movement Disorders
- Medical Imaging and Analysis
- Neurogenetic and Muscular Disorders Research
- Oral and Craniofacial Lesions
Federal Almazov North-West Medical Research Centre
2024
St.Petersburg V.M.Bekhterev Psychoneurological Research Institute
2022
Introduction . Radiomics is a rapidly developing field in oncology visualization aimed at searching for prognostically effective imaging features associated with specific genetic events that determine various characteristics of the disease course. According to numerous studies, presence IDH mutations glial tumors determines longer overall survival. Despite fact biopsy considered be «gold standard» brain differential diagnosis, it though quite difficult perform due complexity surgical access,...
Introduction. Atypical teratoid/rhabdoid tumor (ATRT) of the central nervous system (CNS) belongs to embryonic group, occurs mainly in children under 3 years age and is characterized by an extremely aggressive clinical course unfavorable outcome. However, there not enough data about heterogeneity CNS ATRT role therapeutic prognostic factors patients 1 year 1–3 age. The aim this study was conduct a comparative evaluation treatment results with indicated groups. Materials methods. From 2008...
The Foix-Alajouanine syndrome was originally reported by these authors in 1926, as rapidly progressive vasculitis on the background of a viral infection. pathology represented huge, more than 10 times, dilation either lumen, or walls spinal vessels, arteries, veins. There were no signs thrombosis, malformations. Massive necrosis observed cord. Though plenty observations over past 100 years, most them deal with arteriovenous malformations and/or which had not been revealed originally. We...
There are different views on the nature of cerebral palsy, but no one has been accepted commonly. Since, every new observation this disorder based thorough clinical examination could convert obscurity into clear and simple conception. We report case 4-year-old boy with lower paraplegia speech retardation. The tonus was increased bilaterally in gastrocnemius muscles thigh adductors. muscle decreased iliopsous. Electrophysiological revealed signs excitability motoneurons at level L 2 - S 2....
Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system (CNS) is an aggressive malignant that mainly found in younger children and associated with poor prognosis. Our objectives: to present results treatment CNS AT/RT under 3 years age assess impact various prognostic factors on patient survival. The study was approved by Independent Ethics Committee Scientific Council N.I. Pirogov Russian National Research Medical University Ministry Healthcare Federation. included 106...
The objective was to study changes of an articulate surface (AS) coxofemoral joints (CFJ) at patients with osteoarthrosis (OА), using СТ Methods. group (92 joints), suffering bilateral OА 2nd and 3rd radiological stage tested by СТ. width AS in front, anteromedial, posterolateral, back sides measured; thus all have been preliminary divided two groups: (A) uniform narrowing (B) nonuniform AS. Comparison sizes areas joint space different parts performed.
Abstract BACKGROUND Brain metastases occur in 20-40% of cancer patients. In connection with the development radiosurgical treatment, problem differential diagnosis continued tumor growth and post-radiation changes becomes relevant. The main method treatment secondary lesions is Gamma-Knife. Positron emission tomography 11C-Meth 18F-FET an important monitoring patients brain tumors. MATERIAL AND METHODS We examined 73 metastases. Of these, 36.36% were breast cancer, 39.39% lung 9.00%...
Abstract BACKGROUND Follow-ap assessment of post-therapeutic changes in gliomas 3-4 raids revealed the phenomen metabolic pseudoprogression. This feature was manifested a transistor increase capture radiopharmaceutical. "anomaly" requires study for correct differential diagnosis between progression and pseudoprogression MATERIAL AND METHODS For period from 2019 to 2023, 27 patients aged 24-72 years (average age 55 years) with phenomena grades after combination therapy participated study. The...
Motor neuron diseases (MND) include two main forms - amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). A certain part of these is hereditary, while etiology sporadic cases remains unknown. Both entities are known to develop because motoneurons damage. Difference between them lies in the state descending pyramidal pathways. The pathways SMA intact, as brain neurons not affected, thus pathology restricted anterior horns cord. Meanwhile, most ALS arise due loss both...
Medulloblastomas of the WNT molecular group (MB-WNT) represent smallest MB and account for only 10 % total. This is characterized by a favorable prognosis. Given aggressive treatment regimens MB, reducing intensity therapy prognostically tumors seems justified. Purpose study – to demonstrate results children with MB-WNT determine impact on survival various prognostic factors. The included 85 patients under age 18 who received were followed up from 1993 2022. Median at diagnosis was years...
Possibilities of surgical treatment brain tumors are often limited by localization in the basal ganglia, thalamus or stem. Stereotactic radiation therapy is an important alternative method intracerebral tumors, including lesions metastatic origin. Fractionation stereotactic radiotherapy allowes to overcome limitations radiosurgery case large size tumor located near critical structures brain. This especially important, because stem less radioresistant comparison with other regions. In present...
Melanotic neuroectodermal tumor (MNET) of infants is a rare benign neoplasm detected mainly in children the first year life. Standard therapy consists radical surgical removal tumor. Currently, treatment patients with recurrent and unresectable forms disease relevant. The number publications using polychemotherapy radiation extremely limited. This article describes clinical case occurrence MNET anterior fontanel course. Proton was chosen as an alternative method.