A5007837293- Listeria monocytogenes in Food Safety
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Essential Oils and Antimicrobial Activity
- Microbial Inactivation Methods
- Meat and Animal Product Quality
- Salmonella and Campylobacter epidemiology
- Spinal Fractures and Fixation Techniques
- Probiotics and Fermented Foods
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Food Safety and Hygiene
- Anesthesia and Pain Management
- Animal Nutrition and Physiology
- Language, Metaphor, and Cognition
- Chemokine receptors and signaling
- Food Quality and Safety Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Bee Products Chemical Analysis
- Spinal Cord Injury Research
- Glioma Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Academic and Historical Perspectives in Psychology
- Immunotherapy and Immune Responses
- Spectroscopy and Chemometric Analyses
University of Arizona
2019-2025
University of Winnipeg
2018-2024
University of Manitoba
2013-2023
Health Sciences Centre
2014-2023
University of California, Berkeley
2023
Ottawa Hospital
2020
Dalhousie University
2020
Christie (Canada)
2020
McGill University
2020
Research Network (United States)
2020
To determine the influence of time from injury to surgery on neurological recovery and length stay (LOS) in an observational cohort individuals with traumatic spinal cord (tSCI), we analyzed baseline follow-up motor scores participants Rick Hansen Spinal Cord Injury Registry specifically assess effect early (less than 24 h injury) surgical procedure LOS. One thousand four hundred ten patients who sustained acute tSCIs American Association Impairment Scale (AIS) grades A, B, C, or D were...
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain within the nonstructural protein 3 counteracts host-mediated antiviral adenosine diphosphate-ribosylation signaling. This enzyme is a promising target because catalytic mutations render viruses nonpathogenic. Here, we report massive crystallographic screening and computational docking effort, identifying new chemical matter primarily targeting active site of macrodomain. Crystallographic 2533 diverse fragments...
ABSTRACT: We studied the effectiveness of partial replacement glycerol with citric, lactic, malic, and tartaric acids on antimicrobial activities nisin (205 IU/g protein)‐incorporated soy protein film against Listeria monocytogenes, Escherichia coli O157:H7, Salmonella gaminara. S. gaminara inoculated into 2.6% malic acid‐incorporated films lactic (5.7 3.4 log number colony‐forming units (CFU)/mL, respectively) without (3.2 3.0 CFU/mL, had fewer survivors than HCl‐incorporated (8.6 7.9...
Abstract Tumor cells aberrantly express chemokines and/or chemokine receptors, and some may promote tumor growth metastasis. We examined the expression function of receptor CXCR3 in a syngeneic murine model metastatic breast cancer. By flow cytometry, was detected all mammary cell lines examined. All human cancer also expressed CXCR3, as did immortalized but nontumorigenic MCF-10A line. Interaction ligands, CXCL9, CXCL10, CXCL11, with on highly malignant line 66.1 resulted intracellular...
ABSTRACT Ground beef patties (75% lean) containing synthetic antioxidants, or Fenugreek ( Trigonella foenumgraecum ) extracts were cooked to internal temperature 70°C, and evaluated for storage stability at 4°C. Thiobarbituric acid values of raw samples fenugreek lower than controls (P<0.05). delayed the induction period oxidative rancidity. No differences observed in psychrotrophic bacterial counts, had Hunterlab “a” higher “b” values. Samples with better may be a promising natural...
ABSTRACT How viral and host factors contribute to the severe pathogenicity of H5N1 subtype avian influenza virus infection in humans is poorly understood. We identified three clusters differentially expressed innate immune response genes lungs from (A/Vietnam/1203/04) virus-infected ferrets by oligonucleotide microarray analysis. Interferon were more strongly H5N1-infected ferret than infected with less pathogenic H3N2 subtype. In particular, robust CXCL10 gene expression led us test role...
The effectiveness of whey protein isolate (WPI) coatings incorporated with grape seed extract (GSE), nisin (N), malic acid (MA), and ethylenediamine tetraacetic (EDTA) their combinations to inhibit the growth Listeria monocytogenes, E. coli O157:H7, Salmonella typhimurium were evaluated in a turkey frankfurter system through surface inoculation (approximately 10(6) CFU/g) pathogens. inoculated frankfurters dipped into WPI film forming solutions both without addition antimicrobial agents...
<h3>Importance</h3> Experts debate optimal 25-hydroxyvitamin D (25[OH]D) levels for musculoskeletal health. <h3>Objective</h3> To compare the effects of placebo, low-dose cholecalciferol, and high-dose cholecalciferol on 1-year changes in total fractional calcium absorption, bone mineral density, Timed Up Go five sit-to-stand tests, muscle mass postmenopausal women with vitamin insufficiency. <h3>Design, Setting, Participants</h3> This randomized, double-blind, placebo-controlled clinical...
Liver and lung metastases are the predominant cause of colorectal cancer (CRC)-related mortality. Recent research has indicated that CXCR3/chemokines interactions orchestrate haematopoetic cell movement implicated in metastatic process malignant tumours, including CRC cells to lymph nodes. To date, however, contribution CXCR3 liver metastasis not been addressed. determine whether receptors regulate malignancy-related properties cells, we have used CXCR3-expressing lines human (HT29 cells)...
Abstract Colorectal cancer originates within immunologically complex microenvironments. To date, the benefits of immunotherapy have been modest, except in neoantigen-laden mismatch repair–deficient tumors. Approaches to enhance tumor-infiltrating lymphocytes tumor bed may substantially augment clinical responses. In this article, we report that proteolysis tolerogenic matrix proteoglycan versican (VCAN) strongly correlated with CD8+ T cell infiltration colorectal cancer, regardless repair...
Salmonella Typhimurium and Campylobacter jejuni were inoculated in scalding water, chilled on chicken skins to examine the effects of temperature (50, 55, 60°C) chlorine level water (0, 10, 30, 50 ppm), associated with ages (0 10 h) 8 h), bacterial survival or death. After at 60°C, reductions C. 1.5 6.2 log CFU/ml <1 >2 CFU/cm2 skins; <0.5 >5.5 skins, respectively. The age did not significantly (P > 0.05) affect heat sensitivity. However, increase < reduced effect. In 0-h by 3.3 0.7 CFU/ml,...
Journal Article Purification, amino acid sequence and mode of action bifidocin B produced by Bifidobacterium bifidum NCFB 1454 Get access Z. Yildirim, Yildirim Department Food Science, Center for Safety Quality‐IFSE, University Arkansas, Fayetteville, AR, USA Search other works this author on: Oxford Academic Google Scholar D. K. Winters, Winters M. G. Johnson Applied Microbiology, Volume 86, Issue 1, 1 January 1999, Pages 45–54, https://doi.org/10.1046/j.1365-2672.1999.00629.x Published: 01...
ABSTRACT: This study investigated the effect of nisin added to zein film coatings (Z) coated onto ready‐to‐eat chicken against L. monocytogenes. monocytogenes inoculated samples were dipped into Z dissolved in propylene glycol (ZP) or ethanol (ZE), with and without (N) (1000 IU/g) and/or 1% calcium propionate (CP) then stored at 4 °C 8 for 24 d. After 16 d growth (6.8 log CFU/g) was suppressed by 4.5 5 CFU/g 2.7 counts maintained a nondetectable level from day 0 ZEN, ZPNCP, ZENCP. Zein can...
ABSTRACT The objective of this study was to evaluate the inhibitory effect grape seed extract (GSE), green tea (GTE), nisin and their combinations (nisin with either GSE or GTE) against Listeria monocytogenes . these natural compounds evaluated in phosphate buffer solution (PBS) medium containing approximately 10 9 colony‐forming units (CFU/mL) L. monocytogenes. effectiveness a meat model system by surface inoculation (approximately 6 CFU/g) onto turkey frankfurters. inoculated frankfurters...
ABSTRACT: The effects of hydrophobicity/hydrophilicity edible films against Listeria monocytogenes strain V7 by various nisin concentrations (4.0 ‐ 160 IU/film disk) and pH values ranging from 2.0 to 8.0 were determined the mechanical properties water vapor permeability prepared with or without compared. Surface hydrophobicities (446, 282, 232 142, respectively) whey protein isolates, soy egg albumen wheat gluten determined. As concentration increased, amount inhibition progressively...
A rapid polymerase chain reaction (PCR) method was developed for detection of Listeria monocytogenes in foods. This used a pair primers based on unique region the 16S rRNA sequence L. monocytogenes, which were previously reported by us to yield specific nucleic acid probe. Our included use shorter denaturing time, annealing transition, and an increase number cycles, resulting good sensitivity. Just 3 h PCR plus 1 electrophoresis required. Additional time DNA isolation hybridization not...
In Brief Study Design. A radiographic review of 87 patients with either unilateral or bilateral facet dislocations fracture/dislocations treated anterior cervical discectomy, fusion, and plating. Objective. The primary objective this study was to report the incidence failure factors that would predispose loss alignment. secondary rate pseudarthrosis. Summary Background Data. Biomechanical clinical data conflict regarding appropriate approach method fixation distractive flexion injuries....
Rice bran, an economical, underutilized coproduct of rough rice milling, was used to produce peptide hydrolysates, which were investigated for anticancer activity. Protein hydrolysates prepared by Alcalase hydrolysis under optimized conditions treated further obtain gastrointestinal (GI)-resistant hydrolysates. They fractionated into >50, 10-50, 5-10, and <5 kDa sizes evaluated inhibitory activity on proliferation human colon (Caco-2) liver (HepG2) cancer cell lines Trypan blue dye exclusion...