A5104076416- Liver Disease Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Cardiovascular Function and Risk Factors
- Diet, Metabolism, and Disease
- Heart Failure Treatment and Management
- Diabetes Treatment and Management
- Ion channel regulation and function
- Bariatric Surgery and Outcomes
- Growth Hormone and Insulin-like Growth Factors
- Metabolism, Diabetes, and Cancer
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Hormonal Regulation and Hypertension
- Alcohol Consumption and Health Effects
- Youth, Drugs, and Violence
- Bone health and treatments
- Liver Disease and Transplantation
- Cardiomyopathy and Myosin Studies
- Acute Myocardial Infarction Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac tumors and thrombi
- Hemoglobinopathies and Related Disorders
- Body Contouring and Surgery
Universidade do Porto
2018-2025
Hospital de São João
2022-2024
Cardiovascular Research Center
2024
Czech Academy of Sciences, Institute of Physiology
2023
Diabetes Australia
2023
Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic disease. NAFLD often occurs associated with endocrinopathies. Evidence suggests that endocrine dysfunction may play an important role in development, progression, and severity. Our work aimed to explore summarize crosstalk between different organs, their hormones, dysfunctions. For instance, our results show hyperprolactinemia, hypercortisolemia, polycystic ovary syndrome seem worsen NAFLD’s pathway. Hypothyroidism low...
Background Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism known to contribute an increased risk. It remains uncertain whether thyroid level within the euthyroid range associated with cardiometabolic We aimed evaluate association between function levels risk in a population-based cohort. Methods Eight hundred thirty-five subjects aged ≥45 years from EPIPorto cohort were included. excluded participants TSH, free T4 (FT4), or T3...
Bariatric surgery leads to weight loss and cardiometabolic risk improvement. Although prediabetes remission after bariatric is biologically plausible, data on this topic scarce. We aimed assess rate clinical predictors of in a 4 year follow up period.
Background: An association between hypothyroidism and the risk of Non-alcoholic Fatty Liver Disease (NAFLD) has been suggested. This remains to be elucidated in patients with morbid obesity. Aim: To evaluate thyroid function parameters liver hepatic scores Methods: Patients obesity followed our centre January 2010 July 2018 were included. The ones without evaluation functions excluded. Index (FLI) BARD used as predictors steatosis fibrosis, respectively. Results: We observed a positive TSH...
We aimed to evaluate the association between vitamin D status and hepatic function parameters scores: Fatty Liver Index (FLI, predictor of steatosis) BARD (BMI, AST/ALT ratio DM, fibrosis) in patients with morbid obesity.Cross-sectional study including obesity followed our centre January 2010 July 2018. Patients missing levels or profile were excluded. divided population according two cut-offs (12ng/mL 20ng/mL).The included (n=1124) had an average age 43.3±10.7 years 84.3% female....
Non-alcoholic fatty liver disease (NAFLD) is associated with several other metabolic disorders, which are typically pro-inflammatory states. Body fat content an important marker of health and abdominal harmful cardiometabolic outcomes. We aimed to evaluate the association between risk NAFLD (through Fatty Liver Index (FLI), BMI, AST/ALT ratio, presence diabetes (BARD)), anthropometric parameters, predictors status, in patients morbid obesity, FLI BARD scores markers. have retrospectively...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Thyroid dysfunction is common in patients with heart failure (HF). Impaired conversion of free T4 (FT4) into T3 (FT3) thought to occur these patients, decreasing the availability FT3 and contributing HF progression. In preserved ejection fraction (HFpEF), it not known whether changes thyroid hormones (THs) are associated clinical status outcomes.The objective this study was evaluate association FT3/FT4 ratio TH clinical, analytical, echocardiographic parameters, as well their prognostic...
Thyroid hormones (TH) are crucial for cardiovascular homeostasis. Recent evidence suggests that acute conditions, particularly heart failure (AHF), significantly impair the thyroid axis. Our aim was to evaluate association of function with parameters and short- long-term clinical outcomes in AHF patients. We performed a single-centre retrospective cohort study including patients hospitalized between January 2012 December 2017. used linear, logistic, Cox proportional hazard regression models...
Background: Low levels of triiodothyronine (T3) are common in patients with heart failure (HF). Our aim was to evaluate the effects supplementation low and replacement doses T3 an animal model HF preserved ejection fraction (HFpEF). Methods: We evaluated four groups: ZSF1 Lean (n = 8, Lean-Ctrl), Obese (rat metabolic-induced HFpEF, n 13, HFpEF), treated a dose HFpEF-T3high), low-dose HFpEF-T3low). administered drinking water from weeks 13 24. The animals underwent anthropometric metabolic...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)