A5044733114- Nitric Oxide and Endothelin Effects
- Meteorological Phenomena and Simulations
- Hemoglobin structure and function
- Climate variability and models
- Cardiovascular and exercise physiology
- Tropical and Extratropical Cyclones Research
- Precipitation Measurement and Analysis
- Neuroscience of respiration and sleep
- Erythrocyte Function and Pathophysiology
- Sulfur Compounds in Biology
- Wind and Air Flow Studies
- Neonatal Health and Biochemistry
- Hemoglobinopathies and Related Disorders
- Fluid Dynamics and Turbulent Flows
- Heart Rate Variability and Autonomic Control
- Ocean Waves and Remote Sensing
- Blood groups and transfusion
- Soil Moisture and Remote Sensing
- Lymphoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Atmospheric aerosols and clouds
- Blood disorders and treatments
- High Altitude and Hypoxia
- Electrochemical sensors and biosensors
- Heme Oxygenase-1 and Carbon Monoxide
Wake Forest University
2015-2024
Mahatma Gandhi Memorial Medical College
2023-2024
University of Pittsburgh
2024
Medical College and Hospital, Kolkata
2023
Berry (United States)
2020
Office of the Principal Scientific Adviser
2019
Oil and Natural Gas Corporation (India)
2019
Government of India
2019
University of Swat
2017
National Centre for Medium Range Weather Forecasting
2001-2017
Small increases in physiological nitrite concentrations have now been shown to mediate a number of biological responses, including hypoxic vasodilation, cytoprotection after ischemia/reperfusion, and regulation gene protein expression. Thus, while was until recently believed be biologically inert, it is recognized as potentially important signaling molecule therapeutic agent. Nitrite mediates through its reduction nitric oxide, via reactions with several heme-containing proteins. In this...
The reaction rate between nitric oxide and intraerythrocytic hemoglobin plays a major role in bioavailability modulates homeostatic vascular function. It has previously been demonstrated that the encapsulation of red blood cells restricts its ability to scavenge oxide. This effect attributed either factors intrinsic cell such as physical membrane barrier or external formation an unstirred layer around cell. We have performed measurements uptake by under oxygenated deoxygenated conditions at...
The Indian monsoon is an important component of Earth's climate system, accurate forecasting its mean rainfall being essential for regional food and water security. Accurate measurement various water-related applications, the evaluation numerical models detection attribution trends, but a variety different gridded datasets are available these purposes. In this study, six compared against India Meteorological Department (IMD) dataset, chosen as most representative observed system due to high...
The aim of this study was to evaluate risk factors for longer length stay (los) and mortality among hospitalized children with cancer who have febrile neutropenia.This involved analysis longitudinal data from the University HealthSystem Consortium database 1995 2002. All patients were 21 years or younger, diagnostic codes both neoplastic disease neutropenia at discharge, included.A total 12,446 identified study. los 5 days less 6,799 patients, greater than 5,647 patients. rate 3%. On...
Abstract The upgraded version 7 (V7) of the Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) products is available to user community. In this paper, two successive versions TMPA-3B42 research monitoring product, 6 (V6) and V7, at daily scale are evaluated over India during southwest monsoon with gauge-based data for a 13-yr (1998–2010) period. Over typical rainfall zones, biases improved by 5%–10% in V7 regions higher like west coast, northeastern,...
On 17th June 2013 the state of Uttarakhand in India (Latitude 28.72°N to 31.45°N and Longitude 77.57°E–81.03°E) received more than 340 mm rainfall, which is 375% daily normal (65.9 mm) rainfall during monsoon. This caused heavy floods as well unprecedented damage life property. In this study we aim at assessing performance two deterministic forecast models, Global Forecast System (GFS/T574) Unified Model (NCUM), run NCMRWF, predicting observed over region 17–18th June, 2013. Verification...
Despite the popularity of dietary nitrate supplementation and growing evidence base its potential ergogenic vascular health benefits, there is no direct information about effects on exercising limb blood flow in humans. We hypothesized that acute from beetroot juice would augment increases forearm flow, as well progressive dilation brachial artery, during graded handgrip exercise healthy young men. In a randomized, double-blind, placebo-controlled crossover study, 12 (22 ± 2 years) men...
The onset of menopause and accompanying changes to ovarian hormones often precedes endothelial dysfunction in women. In particular, accelerated impairments macrovascular microvascular function coincide with the loss estrogen, as does impaired responses ischemia-reperfusion (IR) injury. healthy, early postmenopausal women (
Abstract Auxin and polar auxin transport have been implicated in controlling embryo development land plants. The goal of these studies was to determine if are also important during the earliest stages embryos brown alga Fucus distichus. Indole-3-acetic acid (IAA) identified F. distichus mature tissues by gas chromatography-mass spectroscopy. accumulate [3H]IAA an inhibitor IAA efflux, naphthylphthalamic (NPA), elevates accumulation, suggesting presence efflux protein complex similar that...
Abstract Land plants orient their growth relative to light and gravity through complex mechanisms that require auxin redistribution. Embryos of brown algae use similar environmental stimuli developmental polarity. These studies the Fucus distichus examined whether transport are also required during polarization in early embryos already developed tissues. polarize with vector absence a cue. The auxin, indole-3-acetic acid (IAA), efflux inhibitors, such as naphthylphthalamic (NPA), reduced...
S-nitrosothiols are products of nitric oxide (NO) metabolism that have been implicated in a plethora signalling processes. However, mechanisms S-nitrosothiol formation biological systems uncertain, and no efficient protein-mediated process has identified. Recently, we observed ferric cytochrome c can promote S-nitrosoglutathione from NO glutathione by acting as an electron acceptor under anaerobic conditions. In the present study, show this mechanism is also robust oxygenated conditions,...