A5031667012- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Clinical practice guidelines implementation
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Innovation and Socioeconomic Development
- Scoliosis diagnosis and treatment
- Health Policy Implementation Science
- Frailty in Older Adults
- Health disparities and outcomes
- Peripheral Artery Disease Management
- Behavioral Health and Interventions
- Bone and Joint Diseases
- Physical Activity and Health
- Primary Care and Health Outcomes
- Myofascial pain diagnosis and treatment
- Geriatric Care and Nursing Homes
- Knee injuries and reconstruction techniques
- Nutrition and Health in Aging
- Education, Healthcare and Sociology Research
- Bone health and treatments
- Long-Term Effects of COVID-19
- Climate Change and Health Impacts
- Chronic Kidney Disease and Diabetes
- Community Health and Development
University of Edinburgh
2012-2025
Edinburgh Napier University
2018-2022
Keele University
2019
University of Copenhagen
2018
University of Stirling
2015-2017
University of Birmingham
2016
Scottish Collaboration for Public Health Research and Policy
2012-2015
RMIT University
2015
Centre d’histoire de Sciences Po
2013
Western General Hospital
2011
To assess the clinical effectiveness of surgical stabilisation (spinal fusion) compared with intensive rehabilitation for patients chronic low back pain.
<h3>Abstract</h3> <b>Objective</b>: To evaluate a progressive fitness programme for patients with chronic low back pain. <b>Design</b>: Single blind randomised controlled trial. Assessments were carried out before and after treatment by an observer blinded to the study included battery of validated measures. All followed up postal questionnaire six months treatment. <b>Setting</b>: Physiotherapy department orthopaedic hospital. <b>Subjects</b>: 81 pain referred from consultants...
<h3>Abstract</h3> <b>Objective</b> To measure the effectiveness of routine physiotherapy compared with an assessment session and advice from a physiotherapist for patients low back pain. <b>Design</b> Pragmatic, multicentre, randomised controlled trial. <b>Setting</b> Seven British NHS departments. <b>Participants</b> 286 pain more than six weeks9 duration. <b>Intervention</b> Routine or on remaining active physiotherapist. Both groups received book. <b>Main outcome measures</b> Primary was...
Abstract Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients. Many questions remain regarding the function macrophages in normal clearance cryptococcal infection and defects present uncontrolled cryptococcosis. Two current limitations are: 1) The difficulties interpreting studies using isolated context progression infection, 2) use high resolution imaging understanding immune cell behavior during animal infection. Here we describe high-content method...
<h3>Abstract</h3> <h3>Introduction</h3> Caly, Druce (1) reported that ivermectin inhibited SARS-CoV-2 <i>in vitr</i>o for up to 48 h using at 5μM. The concentration resulting in 50% inhibition (IC<sub>50,</sub> 2 µM) was >35x higher than the maximum plasma (Cmax) after oral administration of approved dose when given fasted. <h3>Method</h3> Simulations were conducted an available population pharmacokinetic model predict total (bound and unbound) unbound concentration-time profiles a single...
The aim of this study was to assess the long-term effect a supervised fitness programme on patients with chronic low back pain. design single blind randomised controlled trial follow-up, by postal questionnaire, 2 years after intervention. Oswestry Low Back Pain Disability Index used as outcome measure daily activity affected Eighty-one pain, who were referred physiotherapy department National Health Service orthopaedic hospital, either or control group. Patients in intervention group and...
In Brief Study Design. A prospective cohort. Objective. The aim of this study was to compare the responsiveness a patient specific outcome measure with Oswestry Disability Index v2.1 (ODI) and Roland Morris Questionnaire (RMDQ) for patients mild moderate subacute chronic low back pain. Summary Background Data. Patient measures allow individuals select rate relative importance activities they consider greatest relevance. However, there is paucity research reporting these Methods. Two hundred...
Objective: To assess the feasibility of comparing two types exercise regime aiming to improve mobility and function following knee arthroplasty. Design: A single-blind randomized controlled trial. Subjects: Patients with primary, unilateral osteoarthritis undergoing elective joint replacement. Intervention: Home-based traditional group (TEG) or home-based functional (FEG) discharge from hospital. Outcome measures: These included goniometry; a knee-specific pain score, leg extensor power...
In Brief Study Design. Economic evaluation alongside a pragmatic multicenter randomized controlled trial from the National Health Service (NHS) and societal perspective. Objective. To perform cost-utility analysis of routine physiotherapy treatment compared with an assessment session advice physiotherapist for patients subacute chronic low back pain. Summary Background Data. Lack evidence some types intervention paucity cost-effectiveness data pain has led to controversy uncertainty within...
Qualitative methods are increasingly used to study the process of clinical trials and patients understanding rationale for trials, randomisation reasons taking part or refusing. Patients' understandings inevitably influenced by recruiting clinician's trial, yet relatively little qualitative work has explored clinicians' perceptions trials. This interviewed surgeons shortly after multi-centre, pragmatic RCT in which they had participated been completed. We in-depth interviews with who Spine...
The aim of this study was to investigate the effectiveness pulsed short wave (PSW) in relief pain osteoarthritis hip and knee. Ninety-two patients, mean age 63 years, (34 men 58 women) were randomly allocated one three groups: (1) Active PSW, using dosage found a pilot be non-significantly most effective, (2) Placebo (3) No treatment control group. Nine sessions provided over 3-week period, each application lasting for 15 min. machine modified by manufacturers so that therapist able...
Analysis of outcome data collected prospectively from 250 patients recruited to the UK Spine Stabilization Trial.To compare responsiveness Shuttle Walking Test (SWT), which is an objective measure, with that a disease-specific (the Oswestry Disability Index) and 2 generic EQ-5D SF-36) instruments in chronic low back pain (LBP).Studies assessing performance subjective measures have increased recent years, although there paucity research reporting LBP. The focus investigation has been on...
<sec> <title>BACKGROUND</title> Assistive technologies (AT) are used increasingly in community settings for the management of older adults’ health and care. Despite a rapid increase capabilities uptake these technologies, gaps remain understanding main barriers to their usage. </sec> <title>OBJECTIVE</title> This systematic review investigated facilitators use AT care adults. PROSPERO: CRD42021266656. <title>METHODS</title> Six electronic databases were searched from January 2011 March 2024....
Background Green social prescribing (GSP) aims to link patients nature-based health interventions (NBHIs) through general practitioners (GPs). However, knowledge of GPs’ views on GSP is limited. Aim To explore and the factors influencing these views. Design & setting National cross-sectional survey working lives in Scotland, conducted 2023, which included four questions about GSP. Method Descriptive analysis univariate multivariate (binary logistic) Results 80% ( n =1098) GPs had heard...
Summary111Indium when complexed with oxine is an efficient label of lymphocytes and tumor cells. 111Indium-oxine complex (111InOx) not reutilizable, making it useful for short-term lymphocyte recirculation studies. The spontaneous release 111InOx from cells very low, a isotope in cytotoxicity 111InoX emits two γ photons detectable by nuclear scanning, this potential use the study migration man.
Background: Combining routinely collected health and social care data on older people is essential to advance both service delivery research for this client group. Little available how combine data; article provides an overview of a successful linkage process discusses potential barriers executing such projects.Methods results: We successfully obtained linked within Dundee from three sources: Social Work Department database (30 000 individuals aged 65 years over), healthcare held NHS Tayside...