A5036773318- Allergic Rhinitis and Sensitization
- Endometriosis Research and Treatment
- Contact Dermatitis and Allergies
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Ovarian function and disorders
- Birth, Development, and Health
- Reproductive Biology and Fertility
- Drug-Induced Adverse Reactions
- Antibiotic Use and Resistance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Immunodeficiency and Autoimmune Disorders
- Uterine Myomas and Treatments
- Respiratory and Cough-Related Research
- Dermatology and Skin Diseases
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- Perfectionism, Procrastination, Anxiety Studies
- Obesity, Physical Activity, Diet
- Long-Term Effects of COVID-19
- Neonatal Respiratory Health Research
- Eosinophilic Esophagitis
- Emergency and Acute Care Studies
- HIV/AIDS Research and Interventions
- Pediatric health and respiratory diseases
Dartmouth–Hitchcock Medical Center
2022-2025
Nova Southeastern University
2025
Stony Brook School
2021-2022
Stony Brook University
2018-2022
Port Washington Public Library
2020
McMaster University
2014-2019
Maternal obesity predisposes offspring to metabolic and reproductive dysfunction. We have shown previously that female rat born mothers fed a high-fat (HF) diet throughout pregnancy lactation enter puberty early display aberrant cyclicity. The mechanisms driving this phenotype are currently unknown thus we investigated whether changes in ovarian function were involved. Wistar rats mated randomized to: dams control (CON) or HF from conception until the end of (HF). Ovaries collected fetuses...
Are melatonin receptors (melatonin receptor 1A (MR1A) and 1B (MR1B)) expressed in human endometrium endometriotic tissue, does affect endometrial cell proliferation?Melatonin are eutopic endometrium, endometriomas peritoneal lesions, although to different extents, treatment attenuated estradiol-induced epithelial proliferation culture.Melatonin decreased lesion volume a rat model of endometriosis. Melatonin reduced pain scores analgesic use by women with endometriosis.Basic science study...
Currently, a blood test for the diagnosis of endometriosis, common estrogen-dependent gynecological disease, does not exist. Recent studies suggest that circulating concentrations brain-derived neurotrophic factor (BDNF) have potential endometriosis. However, at present, BDNF can only be measured by ELISA, which requires clinic visit, routine sample, and laboratory testing. Therefore, we developed point-of-care device (EndoChip) use with small volumes collected through finger prick....
Abstract Background Mepolizumab and benralizumab are biologics approved for severe eosinophilic asthma. is an anti-interlukin-5 (IL-5) antibody while anti-interleukin-5 receptor alpha (IL-5Rα) targeting the IL-5 on eosinophils. Both therapies reduce oral corticosteroid requirements asthma exacerbations. However, no head-to-head studies have been published. The aim of present study was to compare efficacy peripheral eosinophil reduction mepolizumab benralizumab. Methods A retrospective chart...
Shrimp and house dust mite (HDM) allergies are common in Canadians. Often, both of these occur the same patient. This may be due to homology tropomyosin or other potentially shared proteins. The aim our study was assess frequency sensitization a shrimp allergic Canadian population.We undertook retrospective chart review patients at an outpatient allergy clinic Kitchener, Ontario, Canada. Our primary endpoint for presence HDM this population. Patients were categorized into approximate...
Based on immunologic phenotypes underlying asthma, use of monoclonal antibody based therapies is becoming the new standard care for severe, corticosteroid refractory clinical symptoms. Patients may qualify one or more these targeted treatments, characteristics and approved indications. However, statistics are not well characterized, particularly in Canadian population.The objective this observational study was to identify describe proportion patients with severe asthma who were eligible...
Summary The association between body mass index (BMI) and poor COVID‐19 outcomes in patients has been demonstrated across numerous studies. However, obesity‐related comorbidities have also shown to be associated with outcomes. purpose of this study was determine whether BMI or obesity‐associated contribute elevated severity non‐elderly, hospitalized (≥25 kg/m 2 ). This a single‐center, retrospective cohort 526 hospitalized, non‐elderly adult (aged 18–64) ≥25 suburban New York from March 6...