A5076913947- Infant Development and Preterm Care
- Maternal Mental Health During Pregnancy and Postpartum
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Family Support in Illness
- Child and Adolescent Psychosocial and Emotional Development
- COVID-19 Impact on Reproduction
- Family and Disability Support Research
- Infant Health and Development
- Cerebral Palsy and Movement Disorders
- Traumatic Brain Injury Research
- Child Nutrition and Feeding Issues
- Childhood Cancer Survivors' Quality of Life
- Breastfeeding Practices and Influences
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer survivorship and care
- Grief, Bereavement, and Mental Health
- Child Abuse and Trauma
- Cancer Risks and Factors
- Family and Patient Care in Intensive Care Units
- COVID-19 Clinical Research Studies
- Medical History and Research
- Bayesian Modeling and Causal Inference
- Dermatological and COVID-19 studies
- Multi-Criteria Decision Making
Policlinico San Matteo Fondazione
2015-2025
Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2008-2022
Fondazione Salvatore Maugeri
2009-2013
Fondazione IRCCS Istituto Neurologico Carlo Besta
2008
Abstract The COVID-19 pandemic is a global traumatic experience for citizens, especially during sensitive time windows of heightened plasticity such as pregnancy and neonatal life. Pandemic-related stress experienced by mothers may act an early risk factor infants’ regulatory capacity development altering maternal psychosocial well-being (e.g., increased anxiety, reduced social support) caregiving environment greater parenting stress, impaired mother–infant bonding). aim the present...
Echovirus 11 (E11) has recently been associated with a series of nine neonatal cases severe hepatitis in France. Here, we present caused by E11 pair twins. In one the neonates, clinical picture evolved to fulminant hepatitis. The genome showed 99% nucleotide identity strains reported Rapid characterisation using next generation sequencing is essential identify new and more pathogenetic variants.
The COVID-19 pandemic represents a collective trauma that may have enduring stress effects during sensitive periods, such as pregnancy. Prenatal result in epigenetic signatures of stress-related genes (e.g., the serotonin transporter gene, SLC6A4) turn influence infants' behavioral development. In April 2020, we launched longitudinal cohort study to assess and vestiges COVID-19-related prenatal exposure mothers infants. was retrospectively assessed at birth. SLC6A4 methylation thirteen CpG...
The COVID-19 pandemic is a collective trauma that threatening citizens' mental health resulting in increased emotional stress, reduced social support, and heightened risk for affective symptoms. present study aimed to investigate the effects of antenatal pandemic-related stress perceived support on symptoms depression anxiety mothers who were pregnant during initial outbreak northern Italy. A sample 281 was enrolled at eight maternity units first hotspot region Participants filled out online...
To clarify the links between parents' prenatal attachment and psychosocial perinatal factors such as maternal depression, anxiety social support.Cross-sectional study including 43 couples with high-risk pregnancy (RP) 37 physiologic (PP). Self-report measures (depression, anxiety, support attachment) are completed by mothers, questionnaire fathers.Depression (p < 0.001) state higher in RP. Both, paternal antenatal is significantly lower RP 0.001; p 0.005) but not related to depression or...
Objective Little is known about the process of becoming a mother in women who experienced breast cancer diagnosis (BC). In this qualitative study, we investigated maternal representations pregnant with experience BC and those no oncological history. Methods A total 38 were recruited, 19 had not. To explore representations, semi-structured interviews conducted analysed through thematic analysis. Results Four main themes identified: fears worries, meaning motherhood, mother–foetus relationship...
Introduction COVID-19 is a highly infectious respiratory disease that rapidly emerged as an unprecedented epidemic in Europe, with primary hotspot Northern Italy during the first months of 2020. Its high infection rate and rapid spread contribute to set risk for relevant psychological stress citizens. In this context, mother–infant health at not only because potential direct exposure virus but also due levels experienced by mothers from conception delivery. Prenatal associates...
Children with neurodevelopmental disabilities (NDs) display several developmental impairments across various domains that impact parent-child interactions, emphasizing the need for effective early interventions. This multi-centric study aimed to evaluate of video-feedback intervention (VFI) on enhancing maternal behavior (i.e., sensitivity) and socio-emotional skills engagement emotionality) in children NDs during normal or stressful interactions Face-to-Face Still-Face, [FFSF]) paradigm. A...
Background: The literature shows that parents of preterm infants are at risk psychological distress and this may impact on the quality parent-child relationship child's development.Aim: This longitudinal study was conducted to examine in relationships between maternal variables, parental protective factors, perinatal infant neurodevelopmental outcome. Furthermore, we explored these variables mother-infant (dyadic synchrony).Subjects methods: A total 29 (GA < 34 weeks) their mothers were...
Abstract Preterm very low birth weight infants (VLBWi) are known to be at greater risk of adverse neurodevelopmental outcome. Identifying early factors associated with outcome is essential in order refer patients for intervention. Few studies have investigated Italian VLBWi. The aim our longitudinal study describe 24 months corrected age an eleven-year cohort 502 preterm VLBWi and identify associations At months, Griffiths’ Mental Developmental Scales were administered. Neurodevelopmental...
The purpose of the study was to explore aspects functioning and health relevant patients with traumatic brain injury (TBI) caregivers TBI explicitly involved in preliminary for Development ICF Core Set using a qualitative research method.The sampling followed maximum variation strategy. To respect this strategy, we different degrees impairment so, some people it not possible join group because their severe cognitive impairment, case interviewed caregivers. focus groups were digitally...
Abstract Aim Although parenting is key to promoting healthy development of at‐risk preterm infants, parents have often restricted access neonatal intensive care units (NICUs). This study aimed assess the effect an early intervention on psychomotor outcome in children at 24 months corrected age. Methods Forty‐two and their were consecutively recruited a level III NICU Northern Italy randomly allocated (two educational peer‐group sessions four individual infant observation sessions) or as...
Abstract Background Prevention of neurodevelopmental impairment due to preterm birth is a major health challenge. Despite advanced obstetric and neonatal care, date there are few neuroprotective molecules available. Melatonin has been shown have anti-oxidant/anti-inflammatory effects reduce brain damage, mainly after hypoxic ischemic encephalopathy. The planned study will be the first aiming evaluate capacity melatonin mitigate premature birth. Method In our prospective, multicenter,...
Abstract Preterm infants cannot counteract excessive reactive oxygen species (ROS) production due to preterm birth, leading an excess of lipid peroxidation with malondialdehyde (MDA) production, capable contributing brain damage. Melatonin (ME), endogenous hormone, and its metabolites, act as a free radical scavenger against ROS. Unfortunately, preterms have impaired antioxidant system, resulting in the inability produce release ME. This prospective, multicenter, parallel groups, randomized,...