A5044189909- Emergency and Acute Care Studies
- Pneumonia and Respiratory Infections
- Birth, Development, and Health
- Sepsis Diagnosis and Treatment
- Respiratory viral infections research
- Asthma and respiratory diseases
- Healthcare Policy and Management
- Child and Adolescent Health
- Obesity, Physical Activity, Diet
- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Pediatric health and respiratory diseases
- Primary Care and Health Outcomes
- Streptococcal Infections and Treatments
- Trauma and Emergency Care Studies
- Breastfeeding Practices and Influences
- Gestational Diabetes Research and Management
- Viral gastroenteritis research and epidemiology
- Childhood Cancer Survivors' Quality of Life
- Neurofibromatosis and Schwannoma Cases
- Neonatal and fetal brain pathology
- Child Nutrition and Feeding Issues
- Eosinophilic Esophagitis
- Celiac Disease Research and Management
- Infant Development and Preterm Care
Erasmus MC - Sophia Children’s Hospital
2016-2025
Erasmus MC
2016-2025
Erasmus University Rotterdam
2014-2025
Panagiotis & Aglaia Kyriakou Children's Hospital
2023
National and Kapodistrian University of Athens
2023
Sotiria General Hospital
2023
Patan Academy of Health Sciences
2023
University College Cork
2022
European Union
2022
Personalis (United States)
2022
The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. designed to identify early environmental and genetic causes causal pathways leading normal abnormal growth, development health life, childhood young This multidisciplinary focuses on several outcomes including behaviour cognition, body composition, eye development, hearing, heart vascular infectious disease immunity, oral facial respiratory health, allergy skin disorders of children their...
The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. designed to identify early environmental and genetic causes of normal abnormal growth, development health during life, childhood focuses on four primary areas research: (1) growth physical development; (2) behavioural cognitive (3) diseases in childhood; (4) healthcare for pregnant women children. In total, 9,778 mothers with delivery date April 2002 January 2006 were enrolled the...
To examine the associations of duration exclusive breastfeeding with infections in upper respiratory (URTI), lower (LRTI), and gastrointestinal tracts (GI) infancy.This study was embedded Generation R Study, a population-based prospective cohort from fetal life onward Netherlands. Rates during first 6 months (never; partial for <4 months, not thereafter; 4-6 months; 4 months) doctor-attended URTI, LRTI, GI until age 12 were assessed by questionnaires available 4164 subjects.Compared...
Correct assessment of gestational age and fetal growth is essential for optimal obstetric management. The objectives this study were, first, to develop charts ultrasound dating pregnancy based on crown-rump length biparietal diameter and, second, derive reference curves normal diameter, head circumference, transverse cerebellar abdominal circumference femur from 10 weeks onwards.A total 8313 pregnant women were included analysis in population-based prospective cohort study. All had repeated...
The objective of this study was to examine the associations between active and passive smoking in different periods pregnancy changing habits during pregnancy, with low birthweight preterm birth. embedded Generation R Study, a population-based prospective cohort from early fetal life onwards Rotterdam, Netherlands. Active were assessed by questionnaires early, mid- late pregnancy. Analyses based on 7098 pregnant women their children. until ascertained not associated Continued after also...
Background Mycoplasma pneumoniae is thought to be a common cause of respiratory tract infections (RTIs) in children. The diagnosis M. RTIs currently relies on serological methods and/or the detection bacterial DNA upper (URT). It conceivable, however, that these diagnostic also yield positive results if carried asymptomatically URT. Positive from tests may therefore not always indicative symptomatic infection. existence asymptomatic carriage has been established. We hypothesized children...
Objectives To determine the validity of Manchester Triage System (MTS) in emergency care for general population patients attending department, children and elderly, commonly used MTS flowcharts discriminators across three different settings. Methods This was a prospective observational study European departments. All consecutive department during 1-year period (2010–2012) were included. Validity assessed by comparing urgency as determined triage nurses with patient according to predefined...
Definitions and assessment methods of fussy/picky eating are heterogeneous remain unclear.We aimed to identify an behavior profile reflecting in children describe characteristics fussy eaters.Eating was assessed with the Child Eating Behavior Questionnaire (CEBQ) 4914 4-year olds a population-based birth cohort study. Latent Profile Analysis (LPA) used profiles based on CEBQ subscales.We found "fussy" (5.6% children) characterized by high food fussiness, slowness eating, satiety...
The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. designed to identify early environmental and genetic causes of normal abnormal growth, development health In total, 9,778 mothers were enrolled in the study. Prenatal postnatal data collection conducted by physical examinations, questionnaires, interviews, ultrasound examinations biological samples. Major efforts have been for collecting specimens including DNA, blood phenotypes urine...
Objectives To examine whether maternal socioeconomic status, as indicated by educational level, is associated with preeclampsia, and if so, to what extent known risk factors for preeclampsia mediate the effect of level. Methods In Generation R Study, a population-based cohort study, we examined data 3547 pregnant women. Odds ratios low, mid-low mid-high level compared high were calculated after adjustment confounders additional selection potential mediators (family history, material factors,...
EUROFIBROMATOSIS TYPE 1 (NF1) is a common autosomal-dominant genetic disorder (incidence 1:3000) caused by mutation in the gene encoding neurofibromin, protein that activates hydrolysis of RAS-bound guanosine triphosphate. 2Neurofibromatosis type characterized various neurocutaneous manifestations, problems fine and gross motor functioning, 3 as well frequent occurrence cognitive disabilities.5][6][7] These have large
To examine the association of breastfeeding with maternal sensitive responsiveness and infant-mother attachment security disorganization.We included 675 participants a prospective cohort study. Questionnaires about practices were administered at 2 6 months postpartum. At 14 months, was assessed in 13-minute laboratory procedure using Ainsworth's sensitivity scales, quality Strange Situation Procedure. Mothers genotyped for oxytocin receptor genes OXTR rs53576 rs2254298. Linear regressions...
To evaluate feasibility, internal consistency, test-retest reliability, and concurrent discriminative validity of the Infant Toddler Quality Life Questionnaire (ITQOL) for parents pre-school children with 12 scales (103-items) covering physical psychosocial domains impact child health on parents, in comparison TNO-AZL Pre-school Children (TAPQOL).
<b>Objective</b> To validate use of the Manchester triage system in paediatric emergency care. <b>Design</b> Prospective observational study. <b>Setting</b> Emergency departments a university hospital and teaching Netherlands, 2006-7. <b>Participants</b> 17 600 children (aged <16) visiting an department over 13 months (university hospital) seven (teaching hospital). <b>Intervention</b> Nurses triaged 16 735/17 patients (95%) using computerised system, which calculated urgency levels from...