- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal pain and rehabilitation
- Medical Practices and Rehabilitation
- Health and Medical Studies
- Physics and Engineering Research Articles
- Medical and Health Sciences Research
- Patient-Provider Communication in Healthcare
- Biomedical and Chemical Research
- Engineering and Materials Science Studies
- Psychosomatic Disorders and Their Treatments
- Consumer behavior in food and health
- Palliative Care and End-of-Life Issues
- Pain Management and Placebo Effect
- Peripheral Artery Disease Management
- Metabolism and Genetic Disorders
- Health, psychology, and well-being
- Pediatric Pain Management Techniques
- Myofascial pain diagnosis and treatment
- Hematological disorders and diagnostics
- Vasculitis and related conditions
- Gastrointestinal motility and disorders
- Pain Mechanisms and Treatments
- German Literature and Culture Studies
- Medical History and Research
- Social and Demographic Issues in Germany
Heidelberg University
2016-2025
Heidelberg University
2024
University Hospital Heidelberg
2014-2023
Acura Kliniken
2023
Center for Rheumatology
2023
Central Institute of Mental Health
2023
Klinik für Psychosomatik
2009-2022
LMU Klinikum
2021
University Hospital Schleswig-Holstein
2021
University of Lübeck
2021
In Brief Study Design. A population-based cross-sectional multiregion postal survey. Objective. To provide a descriptive epidemiology of the prevalence and severity back pain in German adults to analyze sociodemographic correlates for disabling within across regions. Summary Background Data. Back is leading health problem Germany. However, comprehensive evidence on still fragmentary this country. Despite earlier findings concerning large differences regions, systematic explanations remain be...
Age- and gender-matched reference values are essential for the clinical use of quantitative sensory testing (QST). To extend standard test sites QST-according to German Research Network on Neuropathic Pain-to trunk, we collected QST profiles back in 162 healthy subjects. Sensory were within normal interlaboratory differences. revealed lower sensitivity upper than hand, higher foot, but no systematic differences between these trunk sites. Age effects significant most parameters. Females...
Objectives Alterations in the central nervous system leading to higher pain sensitivity have been shown both chronic back (CBP) and fibromyalgia syndrome (FMS). The aim of this study was disclose commonalities differences pathophysiology FMS CBP. Methods We used quantitative sensory testing protocol German Research Network on Neuropathic Pain obtain comprehensive profiles somatosensory functions. comprised thermal mechanical detection thresholds, vibration sharp blunt stimuli. studied 21...
Nonspecific chronic low back pain (CLBP) is a frequent medical condition among middle-aged and older adults. Its detrimental consequences for functional ability quality of life are well known. However, less known about associations chronological age with disability well-being CLBP patients. Coping may be harder advancing due to additional age-associated losses physical, sensory, other resources, resulting in higher lower life. Alternatively, patients feel impaired report than younger because...
Abstract Childhood maltreatment (CM) has been associated with an increased risk of nonspecific chronic low back pain (nsCLBP). However, the mechanisms underlying this association are unclear. Therefore, study considered whether distinct types CM accompanied by specific alterations in somatosensory function. A total 176 subjects nsCLBP and 27 pain-free controls (PCs) were included. The Trauma Questionnaire (CTQ) was used to categorize patients into 2 groups (abused/neglected vs...
Abstract Findings considering conditioned pain modulation (CPM) in chronic back (CBP) are contradictory. This might be because many patients with CBP report further areas of the body, and altered CPM influence spatial extent rather than per se. Therefore, we compared different extent. Patients fibromyalgia syndrome (FMS), for whom impairment is reported most consistently, were measured comparison. Based on clinical evaluation drawings, categorized into local (CLP; n = 53), widespread (CWP;...
Athletes were significantly less sensitive to mechanical pain but showed higher sensitivity vibration compared with normally active controls. Assessment of conditioned modulation suggests that the endogenous pain-inhibitory system is responsive in athletes. There evidence for long-term alterations tolerance among athletes However, scientific data on thresholds this population are inconsistent, and underlying mechanisms differences remain unclear. Therefore, we assessed similarities...
Psychological trauma is associated with an increased risk for chronification of nonspecific chronic back pain (nsCLBP) independent posttraumatic stress disorder (PTSD). However, the mechanisms underlying role psychological in nsCLBP are less clear than PTSD. Therefore, this study considered whether exposure (TE) accompanied by specific alterations perception. The included 56 participants and TE (nsCLBP-TE), 93 without (nsCLBP-W-TE), 31 pain-free controls. All underwent a thorough clinical...
Background: In shared decision making (SDM), the patient and physician reach decisions in partnership.We conducted a trial of SDM training for physicians who treat patients with cancer.Methods: Physicians cancer were invited to participate cluster-randomized carry out together breast or colon faced about their treatment.Decision-related physician-patient conversations recorded.The filled questionnaires immediately after consultations (T 1 ) three months later 2 ).The primary endpoints...
Whether chronic localized pain (CLP) and widespread (CWP) have different mechanisms or to what extent they overlap in their pathophysiology is controversial. The study compared quantitative sensory testing profiles of nonspecific back patients with CLP (n=48) CWP (n=29) fibromyalgia syndrome (FMS) (n=90) pain-free controls (n = 40).The protocol the "German-Research-Network-on-Neuropathic-Pain" was used measure evoked on painful area lower hand (thermal mechanical detection thresholds,...
This S3 guideline takes positions on currently contentious issues in the classification and treatment of fibromyalgia syndrome (FMS).
With the introduction of widespread pain (WSP) as a separate diagnostic code in ICD-11, WSP has now become an own clinical diagnosis independent underlying pathophysiology. Research reported aetiological associations and cardiovascular diseases. However, studies on mortality risk individuals with have inconsistent results. This study investigates whether there is increased establish potential determinants risk. Therefore, we evaluates population-based prospective cohort Framingham Heart...