A5090735662- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Autism Spectrum Disorder Research
- HIV Research and Treatment
- HIV-related health complications and treatments
- Voice and Speech Disorders
- Balance, Gait, and Falls Prevention
- Cerebral Palsy and Movement Disorders
- HIV/AIDS Research and Interventions
- Transportation Systems and Infrastructure
- Drug Solubulity and Delivery Systems
- Transportation Planning and Optimization
- Wildlife-Road Interactions and Conservation
- Underground infrastructure and sustainability
- Electrochemical sensors and biosensors
Mill Valley Public Library
2024
Digital Artefacts (United States)
2021
Abstract Digital health technologies can provide continuous monitoring and objective, real-world measures of Parkinson’s disease (PD), but have primarily been evaluated in small, single-site studies. In this 12-month, multicenter observational study, we whether a smartwatch smartphone application could measure features early PD. 82 individuals with early, untreated PD 50 age-matched controls wore research-grade sensors, smartwatch, while performing standardized assessments the clinic. At...
Digital measures may provide objective, sensitive, real-world of disease progression in Parkinson's (PD). However, multicenter longitudinal assessments such are few. We recently demonstrated that baseline gait, tremor, finger tapping, and speech from a commercially available smartwatch, smartphone, research-grade wearable sensors differed significantly between 82 individuals with early, untreated PD 50 age-matched controls. Here, we evaluated the change these over 12 months observational...
Prevalence estimates of Parkinson’s disease (PD) – the fastest growing neurodegenerative are underestimated due to issues surrounding diagnostic accuracy, symptomatic undiagnosed cases, suboptimal prodromal monitoring, and limited screening access. Remotely monitored wearable devices sensors provide precise, objective, frequent measures motor non-motor symptoms. Here, we used consumer-grade device sensor data from WATCH-PD study develop a PD tool aimed at eliminating gaps between patient...
Prevalence estimates of Parkinson’s disease (PD)—the fastest-growing neurodegenerative disease—are generally underestimated due to issues surrounding diagnostic accuracy, symptomatic undiagnosed cases, suboptimal prodromal monitoring, and limited screening access. Remotely monitored wearable devices sensors provide precise, objective, frequent measures motor non-motor symptoms. Here, we used consumer-grade device sensor data from the WATCH-PD study develop a PD tool aimed at eliminating gap...
Neurological complications including cognitive impairment persist among people with HIV on antiretrovirals; however, screening is not routinely conducted in clinics.Our objective for this study was 3-fold: (1) to determine the feasibility of implementing an iPad-based screener adults seeking care, (2) examine psychometric properties tool, and (3) predictors using tool.A convenience sample participants completed Brain Baseline Assessment Cognition Everyday Functioning (BRACE), which included...
Abstract Digital health technologies can provide continuous monitoring and objective, real world measures of Parkinson’s disease (PD), but have primarily been evaluated in small, single-site studies. In this 12-month, multicenter observational study, we whether a smartwatch smartphone application could measure features early PD. 82 individuals with early, untreated PD 50 age-matched controls wore research-grade sensors, smartwatch, while performing standardized assessments clinic. At home,...
<title>Abstract</title> Digital measures may provide objective, sensitive, real-world of disease progression in Parkinson’s (PD). However, multi-center longitudinal assessments such are few. We recently demonstrated that baseline gait, tremor, finger tapping, and speech from a commercially available smartwatch, smartphone, research-grade wearable sensors differed significantly between 82 individuals with early, untreated PD 50 age-matched controls. Here, we evaluated the change these over 12...
Introduction: FDA guidance recommends continuous glucose monitoring (CGM) for diabetes clinical trials. Real-time in such trials demands high-speed data frameworks. Here, we sought to develop a fully GxP-compliant platform that integrates with CGM devices and rapidly transmits regulatory submission quality study servers. Methods: Software acquired readings directly from Dexcom G6 transmitters sensors via Bluetooth. Live transmitter samples were considered real-time readings; backfill...
FDA guidance recommends continuous glucose monitoring (CGM) for diabetes clinical trials. Real-time in such trials demands high-speed data frameworks. Here, we sought to develop a fully GCP-compliant platform that integrates with CGM devices and rapidly transmits regulatory submission quality study servers. Software acquired readings directly from Dexcom G6 transmitters sensors via Bluetooth. Live transmitter samples were considered real-time readings; backfill excluded classification....
<sec> <title>BACKGROUND</title> Neurological complications including cognitive impairment persist among people with HIV on antiretrovirals; however, screening is not routinely conducted in clinics. </sec> <title>OBJECTIVE</title> Our objective for this study was 3-fold: (1) to determine the feasibility of implementing an iPad-based screener adults seeking care, (2) examine psychometric properties tool, and (3) predictors using tool. <title>METHODS</title> A convenience sample participants...