A5101734132- Vascular Malformations and Hemangiomas
- FOXO transcription factor regulation
- Synthesis of Organic Compounds
- Pancreatic and Hepatic Oncology Research
- Cancer Cells and Metastasis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Synthesis and biological activity
- Cancer, Stress, Anesthesia, and Immune Response
- Cytokine Signaling Pathways and Interactions
XinHua Hospital
2019-2020
Hangzhou First People's Hospital
2018
Cordycepin, the main active ingredient of a traditional Chinese herbal remedy - extracted from Cordyceps sinensis has been demonstrated as very effective anti-inflammatory and antitumor drug. The present study investigated its effect on pancreatic cancer, highly aggressive cancer with extremely poor prognosis due to malignancy, clarified underlying mechanism both in vitro vivo.The viability cordycepin human MIAPaCa-2 Capan-1 cells was determined by colony formation assays. Annexin V/PI...
Osthole is an antitumor compound, which effect on Gallbladder cancer (GBC) has been not elucidated. This study focused its anti-GBC and mechanism both in vitro vivo. The antiproliferation cell lines NOZ SGC-996 were measured by counting kit-8 (CCK-8) colony formation assay. effects apoptosis cycle investigated flow cytometry migration was checked transwell assay the expressions of proteins examined Western Blots. Also, we did in-vivo experiment intraperitoneal injection osthole nude mice....
Abstract Objective To investigate the surgical indication and tactics for liver hemangioma in caudate lobe Methods From January 1994 to July 2019, 137 patients, including 51 males 86 females with average age of 49.2 years old were diagnosed received treatment at five tertiary referral hospitals. Clinical features, correlations between tumor size clinical manifestations, treatments, prognosis analyzed. Results Of patients identified, 40 (29.20%) asymptomatic, whereas other 94 had symptoms...