A5052602622- Sperm and Testicular Function
- MicroRNA in disease regulation
- Circular RNAs in diseases
- High Altitude and Hypoxia
- Osteomyelitis and Bone Disorders Research
- Reproductive Biology and Fertility
- Hematological disorders and diagnostics
- Spaceflight effects on biology
- Wound Healing and Treatments
- Orthopedic Infections and Treatments
- Hydrogen's biological and therapeutic effects
- RNA modifications and cancer
- Testicular diseases and treatments
- Diabetic Foot Ulcer Assessment and Management
- Metabolism and Genetic Disorders
- Photodynamic Therapy Research Studies
Beijing Fengtai Hospital
2020-2025
Hebei University
2024-2025
Peking University
2024
Peking University First Hospital
2024
Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis antitumor processes. Methylation is an epigenetic modification regulates the of DNA coding their interactions, well molecules. Previous studies focused on effects methylation circRNA expression, transport, stability,...
To study the effects of L-carnitine and fructose on semen parameters severe asthenospermia patients by sperm culturing in vitro within 24h. We optimized energy composition antioxidant substances culture medium (based Ham’s F10 medium) orthogonal test for preparing high quality medium. Sperms 60 with idiopathic were collected, cultured 24h, added to different concentrations temperature, whose motility observed determine which is most appropriate concentration temperature. For determining...
The plateau environment impacts male reproductive function, causing decreased sperm quality and testosterone levels. L-carnitine can improve the semen microenvironment. However, role of in a high-altitude remains unclear. In our study, we investigated effects administration Wistar rat system injury model context simulated environment. Rats were randomly divided into normal control group (group A1, A2-low dose A3-high dose) groups B, C-low D-high with 20 rats each group. With exception...
Osteomyelitis is a severely destructive bone disease caused by microbial infections, and currently, no available treatment effectively controls the infection. 5-Aminolevulinic acid second-generation endogenous photosensitizer. This study investigated efficacy of 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) in combination with antibiotics tibial osteomyelitis rabbits. The results illustrated that ALA-PDT alone displayed significant treating osteomyelitis. Animals...
We investigate the efficacy of photodynamic antimicrobial chemotherapy (PACT) and its combination with an antibiotic in treatment diabetic foot ulcers (DFUs) rats using a novel cationic amino acid porphyrin-based photosensitizer. The research findings demonstrate that photosensitizer-mediated PACT exhibits significant therapeutic treating deep rat model DFUs. Moreover, + Antibiotic group displays enhanced angiogenesis, improved tissue maturation, superior wound healing effect. Micro-computed...
Abstract Trial design To study the effects of L-carnitine and fructose on semen parameters severe asthenospermia patients by sperm culturing in vitro within 24h. We optimized energy composition antioxidant substances culture medium (based Ham’s F10 medium) orthogonal test for preparing high quality medium. Sperms 60 with idiopathic were collected, cultured 24h, added to different concentrations temperature, whose motility observed determine which is most appropriate concentration...