A5058785356- Antifungal resistance and susceptibility
- Plant Pathogens and Fungal Diseases
- Fungal Infections and Studies
- Nail Diseases and Treatments
- Mycotoxins in Agriculture and Food
- Essential Oils and Antimicrobial Activity
- Mycobacterium research and diagnosis
- Oral microbiology and periodontitis research
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- Oral health in cancer treatment
- Microbial infections and disease research
- Neutropenia and Cancer Infections
- Antimicrobial Resistance in Staphylococcus
- Mycorrhizal Fungi and Plant Interactions
- Intraperitoneal and Appendiceal Malignancies
- Sinusitis and nasal conditions
- Fungal Biology and Applications
- Microbial Metabolism and Applications
- Advanced Chemical Sensor Technologies
- Beetle Biology and Toxicology Studies
- Microtubule and mitosis dynamics
- Piperaceae Chemical and Biological Studies
- Identification and Quantification in Food
Mazandaran University of Medical Sciences
2014-2024
Vulvovaginal Candidiasis (VVC) is a frequent, complex and cumbersome condition that can cause physical psychological distress for the involved individual. Candida albicans was reported as most common agent of VVC yet it seems we are recently encountering changes in pattern species VVC.In this study assessed different isolated from patients with VVC, residing Sari, Iran.Two hundred thirty-four vulvovaginitis were enrolled study. Samples collected by wet swab. Each vaginal swab examined...
Accurate diagnosis of mucormycosis, a life-threatening fungal infection, remains challenge for physicians.To identify the causative Mucorales in fresh clinical samples and formalin-fixed paraffin-embedded (FFPE) patients with proven mucormycosis by molecular method.Fresh according to EORTC/MSG criteria admitted between 2015 2017 histopathologically FFPE archives collected during 2004-2007 2015-2017 from Mazandaran University-affiliated hospitals northern Iran were included. Seminested PCR...
Several prolonged and significant outbreaks of dermatophytosis caused by Trichophyton indotineae, a new emerging terbinafine-resistant species, have been ongoing in India recent years, since spread to various countries outside Asia. Miltefosine, an alkylphosphocholine, is the most recently approved drug for treatment both visceral cutaneous leishmaniasis. Miltefosine vitro activity against susceptible T. mentagrophytes/T. interdigitale species complex, including limited. The current study...
ABSTRACT A collection of clinical ( n = 47) and environmental 79) Fusarium isolates were tested against 10 antifungal drugs, including 2 novel imidazoles. Luliconazole lanoconazole demonstrated very low geometric mean MIC values 0.005 0.013 μg/ml, respectively, compared with 0.51 μg/ml for micafungin, 0.85 efinaconazole, 1.12 natamycin, 1.18 anidulafungin, 1.31 voriconazole, 1.35 caspofungin, 1.9 amphotericin B, 4.08 itraconazole. Results show that these drugs are potential candidates...
The current study aimed to identify Iranian Nakaseomyces (Candida) glabrata complex species in the clinical isolates and determine their antifungal susceptibility profile.
To study the prevalence of tinea gladiatorum among young wrestlers and dermatophyte contamination wrestling mats from Sari city, capital Mazandaran, a northern province Iran.324 (aged 9-20 years) 7 active clubs in city were examined, skin scrapings obtained 135 suspected having gladiatorum. The scraped samples evaluated with potassium hydroxide. Pleated carpet sterile fragments (5 x 5 cm) used for to survey mat contamination. Sabouraud's dextrose agar without chloramphenicole cyclohexamide...
The in vitro activity of tavaborole, an FDA-approved antifungal drug, was compared to that four agents against 170 clinical fungal isolates originating from patients with onychomycosis. Tavaborole had low all itraconazole, terbinafine, and fluconazole, the principal choices for treatment
Catheter-related blood circulation infection is the most dangerous and serious side-effects of vascular catheters, which leads to enhancement costs, mortality, hospital stay duration, especially in Intensive Care Unit. Regarding this, aim current study was identify prevalence catheter-induced candidemia Tehran Heart Center, a heart Tehran, Iran.This conducted on patients admitted Center for minimum 7 days during 18 months. To detect fungal elements, culture catheter were performed receiving...
The invasive aspergillosis (IA) is a serious opportunistic infection caused by various species of Aspergillus in immunocompromised individuals. Basically, rapid and early diagnosis prevents IA progression. In this study we performed Real Time PCR/ Fluorescence Resonance Energy Transfer (FRET) for hematologic malignancies bone marrow transplant recipients.Sixty two patients with recipients were evaluated Sari Tehran from 2009 to 2010. primer hybridization probe designed amplify the specific...
Hyphal wall protein 1 (HWP1) is an important adhesin which usually expressed on the germ tube and hyphal surface produced by different Candida species. The protein-coding gene was evaluated as a novel identification phylogenetic marker in tropicalis, C. orthopsilosis, parapsilosis glabrata.Initially, four specific primer pairs were designed, target amplified finally sequenced. A total of 77 isolates from species included study. Consensus sequences used for evaluation tree using CLC Genome...
Tuberculosis (TB) continues to be a major public health problem worldwide. This is especially true in Northern Iran, which has high TB prevalence. The chronic nature of this disease further exacerbated if it accompanied by fungal infection, usually remains undiagnosed and thus untreated. Thus, mycotic infections add fatal dimensions pulmonary TB. Our objective was determine the prevalence invasive forms elements sputum samples collected from patients with at reference laboratory Ghaemshahr,...
Fusarium species are filamentous fungi that cause a variety of infections in humans. Because they commonly resistant to many antifungal drugs currently available clinical settings, research into alternative targets fungal cells and therapeutic approaches is required. The activity miltefosine four comparators, amphotericin B, voriconazole, itraconazole, caspofungin, were tested vitro against collection susceptible (n = 68) environmental 42) isolates. Amphotericin B (0.8 μg/mL) had the lowest...
Tinea gladiatorum as the major health concern among combat athletes and most common cause of a decrease in quality their sports activities.This study aimed to determine molecular epidemiology tinea contact Mazandaran Province, Northern Iran.In total, 631 suspected out 4240 ones were screened for this cross-sectional from May 2018 February 2019. The infection was confirmed by direct microscopy culture tests. causative agents identified polymerase chain reaction-restriction fragment length...
Fusarium species are opportunistic human pathogens that remarkably cause fungal infections ranging from superficial to fatal invasive disseminated infections. notoriously resistant the majority of antifungal agents.Therefore, detailed studies regarding in vitro susceptibility required and may lead a better prognosis severe infections.We evaluated 25 drugs against 282 clinical environmental isolates.Fusarium demonstrated high MICs/MECs values most commonly used practice. The geometric mean...
Rhinocerebral mucormycosis is a rare fatal fungal infection which on growing trend, particularly among immunocompromised patients. Immunosuppressive drugs, including corticosteroids and antimetabolites, increase the risk of this infection. Herein, we reported case fulminant rhinocerebral in patient with ulcerative colitis receiving azathioprine corticosteroid.A 58-year-old woman was admitted to hospital state coma an extensive necrosis her nose. She afflicted intestinal bleeding after 1...