- Cervical Cancer and HPV Research
- Genital Health and Disease
- Urological Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- Colorectal and Anal Carcinomas
- Reproductive tract infections research
- Traumatic Brain Injury and Neurovascular Disturbances
- Uterine Myomas and Treatments
- Urinary and Genital Oncology Studies
- Phytochemical and Pharmacological Studies
- Gynecological conditions and treatments
- RNA modifications and cancer
- Infectious Diseases and Mycology
- AI in cancer detection
- RNA Research and Splicing
- Intracerebral and Subarachnoid Hemorrhage Research
- Cancer and Skin Lesions
- S100 Proteins and Annexins
Obstetrics and Gynecology Hospital of Fudan University
2015-2024
First Affiliated Hospital of Xi'an Jiaotong University
2009
Extended high-risk human papillomavirus (hrHPV) genotype testing (hrHPVGT) has emerged as a new strategy to help optimize the efficiency of hrHPV triage.Women with an atypical squamous cells undetermined significance (ASC-US) cervical Papanicolaou test result who underwent hrHPVGT between October 2017 and May 2021 at Obstetrics Gynecology Hospital Fudan University in Shanghai, China, were studied. For hrHPVGT, proprietary multiplex real-time polymerase chain reaction assay was used. viral...
Objective The aim of the study was to analyze clinical outcomes high-grade squamous intraepithelial lesion (HSIL) 6 months after loop electrosurgical excision procedure (LEEP). We explored risk factors persistent cervical HSIL LEEP and evaluated methods follow-up. Patients Methods This retrospective included women who underwent a had diagnosis in their specimen during 2011 2015. purpose determine among these for having disease at 6-month follow-up visit. At visit, each woman cytology...
There is currently no large sample data of cytology, high-risk human papillomavirus (hrHPV), and colposcopy results vaginal intraepithelial neoplasia (VaIN) in women who underwent hysterectomy those did not. We aim to explore the values hrHPV, reports detecting VaIN. A retrospective study diagnosed with VaIN by colposcopy-directed biopsy was performed at Obstetrics Gynecology Hospital Fudan University, China, between January 1, 2014, December 31, 2014. total 529 cases were diagnosed,...
Postmenopausal women are faced with difficulties in colposcopy, such as easy bleeding from epithelial atrophy, and thinning, atypical colposcopy images, unsatisfactory exposure, decreased sensitivity of colposcopy. We aimed to improve the satisfaction postmenopausal evaluate clinical efficacy compound sea-buckthorn oil suppository on topical vaginal pretreatment prior patients who underwent Obstetrics Gynecology Hospital Fudan University April 2023 July 2024 were randomly assigned three...
The objective of this study was to examine the prevalence human papillomavirus 16/18 (HPV-16/18) genotypes and immediate histopathologic correlations in a Chinese population with negative cytology positive high-risk (hrHPV) testing.Patients who had documented follow-up (within 6 months after for intraepithelial lesion or malignancy Papanicolaou [Pap] testing), including examination and/or hrHPV testing, between 2011 2018 were included, data analyzed.Among 1,424,182 Pap tests, 1,333,453...
Punch biopsy is important in the diagnosis of cervical cancer. However, it may fail to detect early cancers. A retrospective study was performed largest academic women's hospital China demonstrate cancer that colposcopy-directed failed detect. Methods. Patients who were diagnosed with high-grade squamous intraepithelial lesion (HSIL), adenocarcinoma situ (AIS), and persistent low-grade (LSIL) via had further undergone loop electrosurgical excision procedure (LEEP) conization included. These...
Objective: The aim of this study is to evaluate the diagnostic accuracy colposcopically directed biopsy (CDB) and loop electrosurgical excision procedure (LEEP) for cervical lesions assess their ability detect glandular involvement. Methods: This retrospective reviewed 4689 that were tested by CDB LEEP at a tertiary hospital. sensitivity, specificity, predictive value ratio involvement detected these two methods analyzed. Results: had sensitivities 95.4% 80.0%, respectively, diagnosing...
To explore the value of CO
Objective: To evaluate the accuracy of colposcopic biopsy on diagnosis cervical adenocarcinoma in situ (AIS) and clinical significance loop electrosurgical excisional procedure (LEEP) treatment AIS invasive adenocarcinoma. Methods: All medical records 193 patients diagnosed as by (or) or LEEP conization from Jan. 2015 to Dec. 2016 Obstetrics Gynecology Hospital Fudan University were retrospectively reviewed. The final was based highest grade pathological after hysterectomy. Results: In...
The aim of the study was to estimate risks cervical intraepithelial neoplasia 2+ (CIN 2+) on loop electrosurgical excisional procedure (LEEP) specimens with diagnosis endocervical curettage (ECC) CIN 1 compared biopsy 1.We performed a retrospective computer-based search for subjects enrolled in Obstetrics and Gynecology Hospital Fudan University. case group comprised women an ECC (ECC results colposcopy-directed ≤CIN 1), control (colposcopy-directed negative findings) diagnosis. Variables,...
Objective: We aimed to explore the factors involved in high-grade squamous intraepithelial lesion (HSIL) or more severe lesions undetected by colposcopy-directed biopsy (CDB). Materials and Methods: retrospectively reviewed 2,427 patients diagnosed with low-grade (LSIL) CDB. After undergoing loop electrosurgical excision procedure (LEEP), 2,023 were classified as having LSIL (group A), 393 HSIL B), 6 cell carcinoma C), 5 adenocarcinoma situ D). Results: The groups D (47.6 ± 4.0) B (39.7 8.2)...
Objective: To estimate risks of cervical intraepithelial neoplasia (CIN) Ⅱ or worse (CINⅡ+) on loop electrosurgical excisional procedure (LEEP) specimens with the diagnosis endocervical curettage (ECC) CINⅠ compared biopsy CINⅠ, and also to investigate hierarchical management scheme ECC based relevant factors CINⅡ+ risk. Methods: (1) A retrospective computer-based research for subjects enrolled in Obstetrics Gynecology Hospital, Fudan University from Jan. 2013 Jun. 2021 was performed. The...