A5021936257- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Testicular diseases and treatments
- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Genital Health and Disease
- Multiple and Secondary Primary Cancers
- Sarcoma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Urologic and reproductive health conditions
- Radiomics and Machine Learning in Medical Imaging
- Urinary and Genital Oncology Studies
- Kidney Stones and Urolithiasis Treatments
- Renal and Vascular Pathologies
- Pediatric Urology and Nephrology Studies
- Organ Donation and Transplantation
- Ovarian cancer diagnosis and treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple Myeloma Research and Treatments
- Ferroptosis and cancer prognosis
- Gestational Trophoblastic Disease Studies
- Healthcare professionals’ stress and burnout
- Cancer-related molecular mechanisms research
- Molecular Biology Techniques and Applications
Instituto Nacional de Cancerología
2014-2025
Columbia University
2024
Icahn School of Medicine at Mount Sinai
2024
National Commission for the Knowledge and Use of Biodiversity
2021
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2011-2018
Instituto Nacional de Investigaciones Nucleares
2018
University of Catania
2012
34 Background: Prostate cancer represents a strong economic and social burden in the world. Imaging, pathology report prostate specific antigen are cornerstone for decision making. PSMA imaging with PET/CT has demonstrated superiority over conventional imaging, however, its availability is limited countries emerging economies. 99mTc-based widely used been favored by development of new inhibitors targeting PSMA. Methods: We analyzed retrospectively 119 men histopathological diagnosis obtained...
Growing teratoma syndrome (GTS) is a rare clinical entity, which presents with enlarging teratomas masses of the retroperitoneum or other locations, occurring during after systemic chemotherapy for treatment nonseminomatous germ cell testis (NSGCT), normalised tumour markers. Awareness this necessary in order to prevent unnecessary and allow optimal management. Prognosis excellent excision these tumors, but surgery has be as complete possible. Surgical resection bulky GTS lesions technically...
Prostate cancer is a leading cause of death in men worldwide. Imaging plays key role disease detection and initial staging. Emerging data has shown the superiority PSMA imaging with PET/CT over conventional for primary diagnoses. Single photon emission computed tomography more available worldwide, agent low cost. The aim this study to compare diagnostic accuracy 99mTc-EDDA/HYNIC-iPSMA SPECT/CT 18F-PSMA-1007 diagnosis prostate impact on clinical In prospective controlled study, 18 patients...
Neuroendocrine differentiation of prostate cancer (NEDPC) includes de novo presentation and secondary to epigenetic changes, referred as therapy-induced neuroendocrine (t-NEPC). Molecular imaging with prostate-specific membrane antigen (PSMA) somatostatin analogues positron emission tomography (PET/CT) in NEDPC have not been validated. 18F-FDG (fluorodeoxyglucose) PET/CT has numerous limitations (PCa) the utility only reported a few series cases. The objective this study is compare lesions...
To our knowledge, this is the first reported case of renal cell carcinoma in kidney horseshoe diagnosed second trimester pregnancy. We performed open radical nephrectomy when pregnancy was completed. Kidney cancer rare during and symptoms can be mimic urinary infection. The diagnosis its management a challenge.
Background: The identification of histopathology in metastatic non-seminomatous testicular germ cell tumors (TGCT) before post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) holds significant potential to reduce treatment-related morbidity young patients, addressing an important survivorship concern. Aim: To explore this possibility, we conducted a study investigating the role computed tomography (CT) radiomics models that integrate clinical predictors, enabling personalized...
Epidemiological data are crucial for adopting primary and secondary prevention strategies to develop screening protocols against prostate cancer (PCa). Despite the comprehensive characterization of PCa across White Black men, there is a lack from Mexican population. This manuscript presents Can.Prost registry that captures trends over past two decades in Mexico City; furthermore, we aimed compare clinical differences oncological outcomes before after promotion early detection actions through...
Post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) in non-seminomatous germ-cell tumor (NSTGCTs) is a complex procedure. We evaluated whether 3D computed tomography (CT) rendering and their radiomic analysis help predict resectability by junior surgeons. The ambispective was performed between 2016–2021. A prospective group (A) of 30 patients undergoing CT segmented using the Slicer software while retrospective (B) with conventional (without reconstruction). CatFisher’s exact...
Post chemotherapy retroperitoneal lymph node dissection (PC-RPLND) in non-seminomatous germ-cell tumours (NSTGCTs) is a complex procedure. We evaluated whether 3D computed tomography (CT) rendering and their radiomics analysis help predict resectability by junior surgeons. The ambispective was performed between 2016-2021. Prospective group (A) of 30 patients undergoing CT were segmented using slicer software while retrospective (B) with conventional (without reconstruction). CatFisher’s...
Abstract Testicular cancer (TCa) is a rare malignancy affecting young men worldwide. Sociodemographic factors, especially socioeconomic level (SEL) and healthcare access, seem to impact TCa incidence outcomes, particularly among Hispanic populations. However, limited research has explored these variables in groups. This study aimed investigate sociodemographic clinical factors Mexico their role health disparities patients. We retrospectively analyzed 244 Mexican cases between 2007 2020 of...
Objective: Studies on the prognostic reliability of Union for International Cancer Control tumor, node, metastasis (TNM) staging system renal cell carcinoma (RCC) predominantly focus clear-cell RCC. Therefore, aim this study was to investigate whether oncological prognosis surgically treated papillary RCC (papRCC) patients is reliably given by current TNM system, analyzing largest database reported date.Materials and methods: Data 2325 papRCC who underwent surgical treatment in 1984– 2015...
Recent data suggest that chronic increment of reactive oxygen species (ROS) may be involved in the development and progression prostatic disease, such as BPH PCa; adipose tissue produces bioactive substances called adipokines, also production ROS. Our study aims to evaluate relationship between obesity oxidative stress prostate disease.
Antecedentes. La función sexual masculina es una interacción compleja de diversos factores psicológicos, neurogénicos y vasculares. Una interrupción en cualquier parte este proceso conduce a disfunción sexual. En México, la afecta entre 30 35% los varones, por lo que necesario contar con un instrumento válido confiable mida funcionalidad esta población. Objetivo. Determinar las propiedades psicométricas del Índice Compuesto para el Cáncer Próstata (EPIC) valoración hombres mexicanos. Método....
43 Background: Prostate cancer (PC) is a leading cause of death in men worldwide. Imaging plays key role disease detection and initial staging. Emerging data has shown the superiority 68 Gallium 18 Fluorine labeled-PSMA imaging with PET/CT over conventional for primary diagnosis. Despite success, there are challenges meeting high demand expensive costs especially low-income countries. These stimulated interest 99m Technetium-labeled-PSMA agents. Single photon emission computer tomography...
Abstract Background Health disparities have been highlighted among patient with prostate adenocarcinoma (PRAD) due to ethnicity. Mexican men present a more aggressive disease than other patients resulting in less favorable treatment outcome. We aimed identify the mutational landscape which could help reduce health minority groups and generate first genomics exploratory study of PRAD patients. Methods Paraffin-embedded formalin-fixed tumoral tissue from 20 early-stage treated at The Instituto...
Health disparities have been highlighted among patient with prostate adenocarcinoma (PRAD) due to ethnicity. Mexican men present a more aggressive disease than other patients resulting in less favorable treatment outcome. We aimed identify the mutational landscape which could help reduce health minority groups and generate first genomics exploratory study of PRAD patients.