A5005086890- Edible Oils Quality and Analysis
- Free Radicals and Antioxidants
- Phytochemicals and Antioxidant Activities
- Bioactive Compounds and Antitumor Agents
- Proteins in Food Systems
- Antioxidant Activity and Oxidative Stress
- Food Chemistry and Fat Analysis
- Essential Oils and Antimicrobial Activity
- Surfactants and Colloidal Systems
- Synthesis of Organic Compounds
- Meat and Animal Product Quality
- Phytochemistry and Biological Activities
- Cholesterol and Lipid Metabolism
- Synthesis of Indole Derivatives
- Spectroscopy and Chemometric Analyses
- Cancer therapeutics and mechanisms
- Microencapsulation and Drying Processes
- Biochemical Analysis and Sensing Techniques
- Dye analysis and toxicity
- Botany, Ecology, and Taxonomy Studies
- Algal biology and biofuel production
- Fermentation and Sensory Analysis
- Biological and pharmacological studies of plants
- Morinda citrifolia extract uses
- Pickering emulsions and particle stabilization
Universidade do Porto
2014-2025
Rede de Química e Tecnologia
1999-2025
Universidade de Vigo
2021
Vall d'Hebron Institut de Recerca
2018
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2018
Association for Innovation and Biomedical Research on Light and Image
2018
University of Southern Denmark
2018
The primary objective of this study was to assess whether the topical administration two neuroprotective drugs (brimonidine and somatostatin) could prevent or arrest retinal neurodysfunction in patients with type 2 diabetes. For purpose, adults aged between 45 75 years a diabetes duration ≥5 an Early Treatment Diabetic Retinopathy Study (ETDRS) level ≤35 were randomly assigned one three arms: placebo, somatostatin, brimonidine. outcome change implicit time (IT) assessed by multifocal...
We determined the interfacial molarities of antioxidants, AOs, hydroxytyrosol (HT), and HT fatty acid esters with chain lengths 1 to 16 carbons in intact olive oil/water/Tween 20 emulsions. The results were compared length effects on oxidative stability same emulsions, a direct correlation was established. Both (AOI) (varying 50-250 times greater than stoichiometric 3.5 × 10(-3) M AO concentration) antioxidant efficiencies show similar parabola-like dependences maximum at C8, consistent...
Abstract Accelerated storage tests are frequently used to assess the oxidative stability of foods and related systems due its reproducibility. Various methods experimental conditions measure lipid oxidation. Differences between laboratories make it necessary determine repeatability reproducibility oxidation performed under same conditions. The objective present interlaboratory study was evaluate outcome a test for two different bulk oils, sunflower oil (SFO) rapeseed (RSO), during period 9...
BACKGROUND The relationships between the hydrophilic–lipophilic balance (HLB) of antioxidants (AOs) and their distributions efficiencies in emulsions are not fully understood. Recent reports indicate that, for series homologous different hydrophobicity, variation efficiency with HLB AO increases alkyl chain length up to a maximum (C3–C8 ester) followed by decrease (cut-off effect). RESULTS We determined caffeic acid derivatives intact soybean employing specifically designed chemical probe...
A detailed quantitative description of the effects antioxidants in inhibiting lipid peroxidation oil-in-water emulsions can be achieved by determining relationships between rates initiation reaction, length induction period preceding propagation step radical oxidation process and effective antioxidant interfacial concentrations. We successfully prepared characterized a series olive nanoemulsions allowed them to spontaneously oxidize. Their oxidative stability was evaluated carrying out...
The anti-inflammatory potential of oleacein, the main polyphenolic compound found in olive oil, and its metabolites were characterized by their effects on RAW 264.7 macrophages challenged with lipopolysaccharide (LPS), ability to inhibit enzymes arachidonic acid metabolism a key role synthesis pro-inflammatory lipid mediators. Oleacein at 12.5 µM significantly decreased amount L-citrulline ●NO generated LPS-stimulated macrophages. Hydroxytyrosol, hydroxytyrosol acetate sulfate also able...
Controlling the interfacial concentrations of antioxidants (AOs) in oil-in-water emulsions can be regarded as a unique approach for increasing efficiency AOs inhibiting oxidation lipids. Classical methods to determine AO distribution binary systems cannot employed and their needs assessed intact emulsion.We have well-established kinetic method homologous series derived chlorogenic acid olive analyse effects hydrophobicity on distributions efficiencies. Results indicate that variations...
Procedures for the easy preparation of a series phytyl phenolipids were developed, yielding esters caffeic, protocatechuic, homoprotocatechuic and dihydrocaffeic acids in high yields (70-95%). Preliminary characterization showed that these new compounds have similar lipo-solubility comparable radical scavenging capacity to natural membrane antioxidant -tocopherol. Cyclic voltammetry analysis lower anodic peak potentials when compared with parental phenolic electron transfer followed an...
A set of procedures was developed for the simple synthesis phytyl phenolipids, which resulted in high yields (70–95%) esters caffeic, protocatechuic, homoprotocatechuic, and dihydrocaffeic acids. Initial characterization revealed that these new compounds exhibited similar radical scavenging activity liposolubility to α-tocopherol, a key antioxidant present membranes. Cyclic voltammetry analysis indicated derivatives had lower anodic peak potentials compared original phenolic acids, with...
Antioxidant efficiencies in emulsions can be optimized by tailoring interfacial concentrations.
The importance of olive polyphenols as bioactive compounds has grown in recent years a result intensive research on their anticancer, antiatherosclerotic and antihypertensive activities. However, there is currently no official method for determining the content oils because technical difficulties determination. Here simple analysis extra virgin oil o-diphenols by visible spectrometry proposed compared with traditional solid phase extraction followed colorimetric determination using sodium...
Abstract We evaluated the effects of oil type, to water ratio, emulsifier concentration, acidity, and temperature on distribution caffeic acid, CA, in emulsions composed stripped olive corn oils, acidic water, Tween 20. CA mainly distributes between interfacial regions because it is sparingly soluble as demonstrated by auxiliary partitioning experiments absence an emulsifier. The distributions were determined intact from values partition constant water‐interfacial region, P W I , under...
In this work, we have evaluated the effects of emulsifier concentration on distribution catechol (1,2‐dihydroxybenzene, CAT) in food‐grade emulsions composed stripped corn oil, acidic water, and Tween 20. Auxiliary experiments binary oil–water mixtures, absence emulsifier, showed that CAT is both oil water soluble (partition constant = 0.34). Addition 20 to prepare kinetically stable creates an interfacial region, now described by two partition constants, between , aqueous . These constants...