G. Anthony Reina

ORCID: 0000-0001-9623-9259
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About
Contact & Profiles
Research Areas
  • Privacy-Preserving Technologies in Data
  • Radiomics and Machine Learning in Medical Imaging
  • Artificial Intelligence in Healthcare and Education
  • vaccines and immunoinformatics approaches
  • Advanced Neural Network Applications
  • Genetics, Bioinformatics, and Biomedical Research
  • AI in cancer detection
  • Glycosylation and Glycoproteins Research
  • Glioma Diagnosis and Treatment
  • Motor Control and Adaptation
  • Machine Learning in Healthcare
  • Tactile and Sensory Interactions
  • Cancer Genomics and Diagnostics
  • Brain Tumor Detection and Classification
  • Heart Failure Treatment and Management
  • Cardiac Imaging and Diagnostics
  • COVID-19 diagnosis using AI
  • Minimally Invasive Surgical Techniques
  • Cardiovascular Effects of Exercise
  • Cardiovascular Issues in Pregnancy
  • Medical Imaging and Analysis
  • Action Observation and Synchronization
  • Domain Adaptation and Few-Shot Learning
  • Rocket and propulsion systems research
  • Calcium Carbonate Crystallization and Inhibition

Intel (United States)
2019-2023

Mission College
2020

Naval Medical Center San Diego
2013

University of Milan
1995-2007

University of Pittsburgh
2004

Washington University in St. Louis
2004

Neurosciences Institute
2001-2003

John Jay College of Criminal Justice
2003

Several studies underscore the potential of deep learning in identifying complex patterns, leading to diagnostic and prognostic biomarkers. Identifying sufficiently large diverse datasets, required for training, is a significant challenge medicine can rarely be found individual institutions. Multi-institutional collaborations based on centrally-shared patient data face privacy ownership challenges. Federated novel paradigm data-private multi-institutional collaborations, where model-learning...

10.1038/s41598-020-69250-1 article EN cc-by Scientific Reports 2020-07-28
Sarthak Pati Ujjwal Baid Brandon Edwards Micah Sheller Shih‐Han Wang and 95 more G. Anthony Reina Patrick Foley А. Д. Груздев Deepthi Karkada Christos Davatzikos Chiharu Sako Satyam Ghodasara Michel Bilello Suyash Mohan Philipp Kickingereder Gianluca Brugnara Chandrakanth Jayachandran Preetha Felix Sahm Klaus Maier‐Hein Maximilian Zenk Martin Bendszus Wolfgang Wick Evan Calabrese Jeffrey D. Rudie Javier Villanueva‐Meyer Soonmee Cha Madhura Ingalhalikar Manali Jadhav Umang Pandey Jitender Saini John W. Garrett Matthew Larson Robert Jeraj Stuart Currie Russell Frood Kavi Fatania Raymond Y. Huang Ken Chang Carmen Balañá Jaume Capellades Josep Puig Johannes Trenkler Josef Pichler Georg Necker Andreas Haunschmidt Stephan Meckel Gaurav Shukla Spencer Liem Gregory S. Alexander Joseph S. Lombardo Joshua D. Palmer Adam E. Flanders Adam P. Dicker Haris I. Sair Craig Jones Archana Venkataraman Meirui Jiang Tiffany Y. So Cheng Chen Pheng‐Ann Heng Qi Dou Michal Kozubek Filip Lux Jan Michálek Petr Matula Miloš Keřkovský Tereza Kopřivová Marek Dostál Václav Vybíhal Michael A. Vogelbaum J. Ross Mitchell Joaquim M. Farinhas Joseph A. Maldjian Chandan Ganesh Bangalore Yogananda Marco C. Pinho Divya Reddy James Holcomb Benjamin Wagner Benjamin M. Ellingson Timothy F. Cloughesy Catalina Raymond Talia C. Oughourlian Akifumi Hagiwara Chencai Wang Minh‐Son To Sargam Bhardwaj Chee Chong Marc Agzarian Alexandre X. Falcão Samuel Botter Martins Bernardo Corrêa de Almeida Teixeira F Sprenger David Menotti Diego Rafael Lucio Pamela LaMontagne Daniel S. Marcus Benedikt Wiestler Florian Kofler Ivan Ezhov Marie Metz

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple sites. However, such centralization challenging scale (or even not feasible) due various limitations. Federated ML (FL) provides an alternative train accurate generalizable models, only numerical model updates. Here we present findings the largest FL study...

10.1038/s41467-022-33407-5 article EN cc-by Nature Communications 2022-12-05

Abstract Medical artificial intelligence (AI) has tremendous potential to advance healthcare by supporting and contributing the evidence-based practice of medicine, personalizing patient treatment, reducing costs, improving both provider experience. Unlocking this requires systematic, quantitative evaluation performance medical AI models on large-scale, heterogeneous data capturing diverse populations. Here, meet need, we introduce MedPerf, an open platform for benchmarking in domain....

10.1038/s42256-023-00652-2 article EN cc-by Nature Machine Intelligence 2023-07-17

Single-unit activity in area M1 was recorded awake, behaving monkeys during a three-dimensional (3D) reaching task performed virtual reality environment. This study compares motor cortical discharge rate to both the hand's velocity and arm's joint angular velocities. Hand is considered parameter of extrinsic space because it measured Cartesian coordinate system monkey's workspace. Joint intrinsic relative adjacent arm/body segments. In initial analysis, as difference hand position or posture...

10.1152/jn.2001.85.6.2576 article EN Journal of Neurophysiology 2001-06-01

A motor illusion was created to separate human subjects' perception of arm movement from their actual during figure drawing. Trajectories constructed cortical activity recorded in monkeys performing the same task showed that represented primary cortex, whereas visualized, presumably perceived, trajectories were found ventral premotor cortex. Perception and action representations can be differentially recognized brain may contained structures.

10.1126/science.1087788 article EN Science 2004-01-15

This manuscript describes the first challenge on Federated Learning, namely Tumor Segmentation (FeTS) 2021. International challenges have become standard for validation of biomedical image analysis methods. However, actual performance participating (even winning) algorithms "real-world" clinical data often remains unclear, as included in are usually acquired very controlled settings at few institutions. The seemingly obvious solution just collecting increasingly more from institutions such...

10.48550/arxiv.2105.05874 preprint EN other-oa arXiv (Cornell University) 2021-01-01

Convolutional neural network (CNN) models perform state of the art performance on image classification, localization, and segmentation tasks. Limitations in computer hardware, most notably small memory size deep learning accelerator cards, prevent relatively large images, such as those from medical satellite imaging, being processed a whole their original resolution. A fully convolutional topology, U-Net, is typically trained down-sampled images inference resolution, by simply dividing...

10.3389/fnins.2020.00065 article EN cc-by Frontiers in Neuroscience 2020-02-07

Abstract Objective. De-centralized data analysis becomes an increasingly preferred option in the healthcare domain, as it alleviates need for sharing primary patient across collaborating institutions. This highlights consistent harmonized curation, pre-processing, and identification of regions interest based on uniform criteria. Approach. Towards this end, manuscript describes Fe derated T umor S egmentation (FeTS) tool, terms software architecture functionality. Main results. The aim FeTS...

10.1088/1361-6560/ac9449 article EN Physics in Medicine and Biology 2022-09-22

Abstract Background Statins represent a modern mainstay of the drug treatment coronary artery disease and acute syndromes. Reduced aerobic work performance slowed VO 2 kinetics are established features clinical picture post‐myocardial infarction (MI) patients. We tested hypothesis that statin therapy improves exercise in normocholesterolaemic post‐MI Materials methods According to double‐blinded, randomized, crossover placebo‐controlled study design, 18 patients with uncomplicated recent (3...

10.1111/j.1365-2362.2007.01805.x article EN European Journal of Clinical Investigation 2007-05-26

Using medical imaging as case-study, we demonstrate how Intel-optimized TensorFlow on an x86-based server equipped with 2nd Generation Intel Xeon Scalable Processors large system memory allows for the training of memory-intensive AI/deep-learning models in a scale-up configuration. We believe our work represents first deep neural network having footprint (~ 1 TB) single-node server. recommend this configuration to scientists and researchers who wish develop large, state-of-the-art AI but are...

10.48550/arxiv.2003.08732 preprint EN other-oa arXiv (Cornell University) 2020-01-01

Medical AI has tremendous potential to advance healthcare by supporting the evidence-based practice of medicine, personalizing patient treatment, reducing costs, and improving provider experience. We argue that unlocking this requires a systematic way measure performance medical models on large-scale heterogeneous data. To meet need, we are building MedPerf, an open framework for benchmarking machine learning in domain. MedPerf will enable federated evaluation which securely distributed...

10.48550/arxiv.2110.01406 preprint EN cc-by-nc-nd arXiv (Cornell University) 2021-01-01

Deep learning models for semantic segmentation of images require large amounts data. In the medical imaging domain, acquiring sufficient data is a significant challenge. Labeling image requires expert knowledge. Collaboration between institutions could address this challenge, but sharing to centralized location faces various legal, privacy, technical, and data-ownership challenges, especially among international institutions. study, we introduce first use federated multi-institutional...

10.48550/arxiv.1810.04304 preprint EN other-oa arXiv (Cornell University) 2018-01-01

Abstract BACKGROUND Training deep learning algorithms requires large amounts of data, which is a significant challenge in the medical domain, and particularly neuro-oncology, where ample data can only be found multi-institutional collaborations. The current paradigm for collaborations based on pooled datasets that has always faced privacy, legal, technical, data-ownership concerns. In this study we evaluate hypothesis federated provide method to overcome these concerns facilitate shift...

10.1093/neuonc/noz175.737 article EN Neuro-Oncology 2019-11-01
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