Marek Dostál
A5010039100- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Medical Imaging and Analysis
- Radiomics and Machine Learning in Medical Imaging
- Privacy-Preserving Technologies in Data
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Bone and Joint Diseases
- Advanced X-ray and CT Imaging
- Brain Tumor Detection and Classification
- Systemic Sclerosis and Related Diseases
- Spine and Intervertebral Disc Pathology
- Scoliosis diagnosis and treatment
- Multiple Sclerosis Research Studies
- Radiation Dose and Imaging
- Pancreatic and Hepatic Oncology Research
- Cervical and Thoracic Myelopathy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Infectious Diseases and Tuberculosis
- Spinal Dysraphism and Malformations
- Medical Image Segmentation Techniques
- Colorectal Cancer Surgical Treatments
- Spinal Fractures and Fixation Techniques
- Venous Thromboembolism Diagnosis and Management
Masaryk University
2017-2025
University Hospital Brno
2018-2025
Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple sites. However, such centralization challenging scale (or even not feasible) due various limitations. Federated ML (FL) provides an alternative train accurate generalizable models, only numerical model updates. Here we present findings the largest FL study...
Abstract In a companion paper by Cohen-Adad et al . we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This was used to acquire single subject dataset across 19 centers multi-subject 42 (for total of 260 participants), spanning three main manufacturers: GE, Philips Siemens. Both datasets are publicly available via git-annex. Data were analysed using Spinal Cord Toolbox produce...
To evaluate the contribution of F-18 FDG-PET/MRI in search for etiology inflammation unknown origin (IUO) and fever (FUO).
Background: Lumbar paraspinal muscles (LPM) are a part of the deep spinal stabilisation system and play an important role in stabilising lumbar spine trunk. Inadequate function these is thought to be essential aetiological factor low back pain, several neuromuscular diseases characterised by dysfunction LPM. The main aims our study were develop methodology for LPM assessment using advanced magnetic resonance imaging (MRI) methods, including manual segmentation process, confirm measurement...
Biliary drainage is then one of the necessary procedures to help patients suffering from icterus reduce serum bilirubin levels and relieve symptoms. The aim this study was identifying risk factors for survival in with cholangiocarcinoma (CCA) treated percutaneous transhepatic biliary (PTBD) develop a simple scoring system predicting PTBD insertion. This single-centre retrospective included 175 consecutive undergoing extrahepatic CCA (perihilar distal). Prognostic affecting were analysed. A...
Abstract Clinical research emphasizes the implementation of rigorous and reproducible study designs that rely on between-group matching or controlling for sources biological variation such as subject’s sex age. However, corrections body size (i.e. height weight) are mostly lacking in clinical neuroimaging designs. This investigates importance parameters their relationship with spinal cord (SC) brain magnetic resonance imaging (MRI) metrics. Data were derived from a cosmopolitan population...
Muscle magnetic resonance imaging (MRI) is an emerging method in the diagnosis and monitoring of muscular dystrophies. This cross-sectional, comparative study aimed to evaluate quantitative MRI (qMRI) parameters lumbar paraspinal muscles (LPM) myotonic dystrophy type 2 (DM2), assess their relationship with functional examination, evolution aging. The enrolled 37 DM2 patients 90 healthy volunteers (HV) who were matched based on physiological create 35 pairs. Utilizing a 6-point Dixon gradient...
Degenerative cervical spinal cord compression is becoming increasingly prevalent, yet the MRI criteria that define are vague, and vary between studies. This contribution addresses detection of by means Spinal Cord Toolbox (SCT) assesses variability morphometric parameters extracted with it.Prospective cross-sectional study. Two types examination, 3 1.5 T, were performed on 66 healthy controls 118 participants compression. Morphometric from 3T obtained (cross-sectional area, solidity,...
Abstract Clinical research emphasizes the implementation of rigorous and reproducible study designs that rely on between-group matching or controlling for sources biological variation such as subject’s sex age. However, corrections body size (i.e. height weight) are mostly lacking in clinical neuroimaging designs. This investigates importance parameters their relationship with spinal cord (SC) brain magnetic resonance imaging (MRI) metrics. Data were derived from a cosmopolitan population...
Purpose Spinal cord gray‐matter imaging is valuable for a number of applications, but remains challenging. The purpose this work was to compare various MRI protocols at 1.5 T, 3 and 7 T visualizing the gray matter. Methods In vivo data cervical spinal were collected from nine different centers. Data processing consisted automatically segmenting its matter co‐registering back‐to‐back scans. We computed SNR using two methods (SNR_single single scan SNR_diff difference between scans) white/gray...
Degenerative cervical myelopathy (DCM) represents the final consequence of a series degenerative changes in spine, resulting spinal canal stenosis and mechanical stress on cord. This process leads to subsequent pathophysiological processes cord tissues. The primary mechanism injury is compression cord, detectable by magnetic resonance imaging (MRI), serving as hallmark for diagnosing DCM. However, relative resilience clinical-radiological discordance, i.e., some individuals may exhibit MRI...
To evaluate and compare the diagnostic power of [
BACKGROUND AND OBJECTIVES: Meningioma, the most common primary intracranial tumor, presents challenges in surgical treatment because of varying tissue stiffness. This study explores molecular background meningioma stiffness, a critical factor planning and prognosis, focusing on utility microRNAs (miRNAs) as diagnostic biomarkers METHODS: Patients with meningiomas treated surgically at University Hospital Brno were included this study. Total RNA, isolated from tumor samples, underwent quality...
Aim of this pilot study was to assess blood perfusion bowel in resection lines by means the infrared thermal imaging order choose best place for anastomosis. The paper brings a first experience with used colorectal surgery operation from initial observation patient T3 adenomatous carcinoma no lymph node metastasis. obtained images show clear boundary between parts intestine and without it. proposed position colon identified camera is accordance routinely designated position. Infrared seems...
Background Segmentation of the gray and white matter (GM, WM) human spinal cord in MRI images as well analysis diffusivity are challenging. When appropriately segmented, diffusion tensor imaging (DTI) might be beneficial diagnosis prognosis several diseases. Purpose To evaluate applicability a semiautomatic algorithm provided by ITK‐SNAP classification mode (CLASS) for segmenting cervical GM, WM analyzing DTI parameters. Study Type Prospective. Subjects Twenty healthy volunteers. Sequences...
Scoliosis embodies the most frequent three-dimensional spinal deformity in children. Only timely treatment during growth of spine may significantly reduce related health problems inflicted by on adults. The results obtained via conservative therapy are problematic, and a certain degree curvature already requires surgical that at time writing consists repeated surgeries posing high risk complications. aim is to use model for computer based simulation changes stress idiopathic syndromic...