A5069936536- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Parkinson's Disease Mechanisms and Treatments
- Atomic and Subatomic Physics Research
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- MRI in cancer diagnosis
- Morphological variations and asymmetry
- Non-Invasive Vital Sign Monitoring
- 3D Shape Modeling and Analysis
- Epilepsy research and treatment
- Cardiac Imaging and Diagnostics
- Multiple Sclerosis Research Studies
- Sleep and Wakefulness Research
- Schizophrenia research and treatment
- Tensor decomposition and applications
- Transcranial Magnetic Stimulation Studies
- Protease and Inhibitor Mechanisms
- Spinal Dysraphism and Malformations
- NMR spectroscopy and applications
- Neurobiology of Language and Bilingualism
- Lysosomal Storage Disorders Research
- Optical Coherence Tomography Applications
- Fetal and Pediatric Neurological Disorders
- Mental Health Research Topics
Central European Institute of Technology
2017-2024
Central European Institute of Technology – Masaryk University
2017-2024
University Hospital Brno
2023
Masaryk University
2021-2023
ORCID
2020
The choroid plexus (ChP) is part of the blood-cerebrospinal fluid barrier, regulating brain homeostasis and brain's response to peripheral events. Its upregulation enlargement are considered essential in psychosis. However, timing ChP has not been established. This study introduces a novel magnetic resonance imaging-based segmentation method examine volumes two cohorts individuals with first sample consists 41 early course psychosis (mean duration illness = 1.78 years) 30 healthy...
Introduction While progressive MRI brain changes characterize advanced Parkinson's disease (PD), little has been discovered about structural alterations in the earliest phase of disease, i.e. patients with motor symptoms and normal cognition. Our study aimed to detect grey matter (GM) white (WM) PD without cognitive impairment. Methods Twenty twenty-one healthy controls (HC) were tested for attention, executive function, working memory, visuospatial language domains. High-resolution...
The advent of new, advanced quantitative MRI metrics allows for in vivo evaluation multiple biological processes highly relevant ageing. presented study combines several parameters hypothesised to detect distinct characteristics as myelin density, cellularity, cellular membrane integrity and iron concentration. 116 healthy volunteers, continuously distributed over the whole adult age span, underwent a multi-modal protocol acquisition. Scatterplots individual revealed that certain protocols...
This publication describes an original simple low-cost MR fully-compatible and safe fiber-optic breathing sensor (FOBS), which can be used for respiratory triggering monitoring the development of rate within environment can, thus, serve as prevention from hyperventilation syndrome. The is created by encapsulation Bragg grating into conventional nasal oxygen cannulas. immune to minor patient movements, thus limiting movement artifacts a minimum. Thanks this fact it retrospective/prospective...
Abstract Diffusion magnetic resonance imaging (dMRI) proved promising in patients with non-myelopathic degenerative cervical cord compression (NMDCCC), i.e., without clinically manifested myelopathy. Aim of the study is to present a fast multi-shell HARDI-ZOOMit dMRI protocol and validate its usability detect microstructural myelopathy NMDCCC patients. In 7 young healthy volunteers, 13 age-comparable controls, 18 mild 15 severe NMDCCC, provided higher signal-to-noise ratio, enhanced...
Abstract Many methods applied to data acquired by various imaging modalities have been evaluated for their benefit in localizing lesions magnetic resonance (MR) negative epilepsy patients. No approach has proven be a stand‐alone method with sufficiently high sensitivity and specificity. The presented study addresses the potential of automated fusion results individual presurgical evaluation. We collected electrophysiological, MR, nuclear from 137 patients pharmacoresistant...
Abstract The objective was to determine the optimal combination of multimodal imaging methods (IMs) for localizing epileptogenic zone (EZ) in patients with MR-negative drug-resistant epilepsy. Data from 25 focal epilepsy (age 30 ± 10 years, 16M/9F) who underwent surgical resection EZ and 110 healthy controls 31 9 years; 56M/54F) were used evaluate IMs based on 3T MRI, FDG-PET, HD-EEG, SPECT. Patients successful outcomes and/or positive histological findings evaluated. From 38 calculated per...
This study focuses on white matter alterations in pharmacoresistant epilepsy patients with no visible lesions the temporal and frontal lobes clinical MRI (i.e. MR-negative) confirmed by resective surgery. The aim of was to extend knowledge about group-specific neuropathology MR-negative epilepsy. We used fixel-based analysis (FBA) that overcomes limitations traditional diffusion tensor image analysis, mainly within-voxel averaging multiple crossing fibres. Group-wise comparisons fixel...
Planar electromagnetic phantom design for measurement and imaging using NMR has been performed. Electromagnetic computation testing on a 0.178 Tesla Esaote Opera imager were accomplished. The classical geometrical chemical phantoms are generally used of systems. They simple cylindrical or rectangular objects with different dimensions shapes holes filled specially prepared water solutions. In our experiments homogeneous (reference medium) - container was used. resultant image represents the...
This study describes a pilot clinical validation of new low-cost system for the continuous monitoring human body's cardiorespiratory activities within magnetic resonance examination area. primarily focuses on cardiac activity and related triggering. The patented tested by authors is based seismocardiography (SCG). was conducted 18 subjects Siemens Prisma 3T MR scanner. Standard anatomical diffusion sequences were used to test monitoring. A wide range commonly diagnostic imaging heart means...
Purpose Spinal cord gray‐matter imaging is valuable for a number of applications, but remains challenging. The purpose this work was to compare various MRI protocols at 1.5 T, 3 and 7 T visualizing the gray matter. Methods In vivo data cervical spinal were collected from nine different centers. Data processing consisted automatically segmenting its matter co‐registering back‐to‐back scans. We computed SNR using two methods (SNR_single single scan SNR_diff difference between scans) white/gray...
The research on possible cerebral involvement in Crohn's disease (CD) has been largely marginalized and failed to capitalize recent developments magnetic resonance imaging (MRI).
Objectives: We assessed the relationship between emotional awareness (e.g., ability to identify and differentiate our own feelings of others) regional brain volumes in healthy schizophrenia groups. Methods: Magnetic resonance images 29 subjects with 33 matched controls were acquired. Brain gray matter was parcellated using FreeSurfer 28 regions interest associated analyzed. All participants Levels Emotional Awareness Scale (LEAS) Self Other. LEAS scores correlated volume for each hemisphere...
This first-ever study demonstrates the applicability of a fiber Bragg grating (FBG) system for MR cardiac triggering cardiovascular magnetic resonance at 3 Tesla. The unique patented senses body movements caused by activity using non-invasive ballistocardiography (BCG) sensor. pilot research compares novel FBG-based with clinically used systems based on electrocardiography (ECG) and pulse oximetry (POX). pre-clinical was conducted 8 subjects Siemens Prisma 3T Scanner. images from two basic...
This pilot pre-clinical study demonstrates the applicability of a new type pneumatic cardiac triggering (PCT) for imaging. The research compares novel FPGA-based pad monitoring system using ballistocardiography (BCG) with conventional systems based on electrocardiography (ECG) and photoplethysmography (PPG). implemented enables without need to fix sensors patient's body. unique approach has potential reduce preparation time examination itself increase comfort. was conducted 10 subjects at...
This pilot comparative study evaluates the usability of alternative approaches to magnetic resonance (MR) cardiac triggering based on ballistocardiography (BCG): fiber-optic sensor (O-BCG) and pneumatic (P-BCG). The comparison includes both objective subjective assessment proposed sensors in with a gold standard ECG-based triggering. evaluation included several image quality (IQA) parameters, whereas analysis was performed by 10 experts rating diagnostic (scale 1 - 3, corresponding best 3...
We’ve built this digital research platform to provide academics everywhere with fast, stable and secure access our library of over 110,000 scholarly books 800,000 journal articles. tested the in close cooperation leading academic institutions. If you have any questions or notice something doesn’t quite work as it should, please visit <a href="/publishing/faq?lang=en" class="text-primary">Help/FAQ</a> page let us know.
Abstract The effectivity of diffusion-weighted MRI methods in detecting the epileptogenic zone (EZ) was tested. Patients with refractory epilepsy (N=25) who subsequently underwent resective surgery were recruited. First, extent white matter (WM) asymmetry from mean kurtosis (MK) calculated order to detect lobe strongest impairment. Second, a newly developed metric used, reflecting selection brain areas concurrently i ncreased D iffusivity, r educed fractional A nisotropy, and K urtosis...
Background: The research of primary progressive multiple sclerosis (PPMS) has not been able to capitalize on recent progresses in advanced magnetic resonance imaging (MRI) protocols. Objective: presented cross-sectional study evaluated the utility four different MRI relaxation metrics and diffusion-weighted PPMS. Methods: Conventional free precession T1 T2, rotating frame adiabatic T1ρ T2ρ combination with parameters were acquired 13 PPMS patients age- sex-matched controls. Results: T1ρ, a...