Sumiya Kuroda
A5090714627- Neurobiology and Insect Physiology Research
- Animal Behavior and Reproduction
- Insect and Arachnid Ecology and Behavior
- Plant and Biological Electrophysiology Studies
- Fossil Insects in Amber
- Neural Networks and Applications
- Physiological and biochemical adaptations
Harvard University
2022-2024
Summary Like the vertebrate spinal cord, insect ventral nerve cord (VNC) mediates limb sensation and motor control. Here, we apply automated tools for electron microscopy volume alignment, neuron segmentation, synapse prediction toward creating a connectome of an adult female Drosophila VNC. To interpret connectome, it is crucial to know its relationship with rest body. We therefore mapped muscle targets leg wing neurons in by comparing their morphology genetic driver lines, dye fills, X-ray...
Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. MN activity coordinated complex premotor networks that allow individual muscles contribute many different behaviors. Here, we use connectomics analyze wiring logic circuits controlling Drosophila leg and wing. We find both cluster into modules link MNs innervating with related functions. Within most modules, synaptic weights each neuron are proportional size their target...