- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Animal Behavior and Reproduction
- Plant and animal studies
- Physiological and biochemical adaptations
- Fossil Insects in Amber
- Urological Disorders and Treatments
- Animal Ecology and Behavior Studies
- Innovations in Educational Methods
- International Business and FDI
- Adipose Tissue and Metabolism
- Ethics in Clinical Research
- Diptera species taxonomy and behavior
- Adversarial Robustness in Machine Learning
- Innovative Teaching Methods
- Testicular diseases and treatments
- Plant and Biological Electrophysiology Studies
- Corporate Finance and Governance
- Pharmacovigilance and Adverse Drug Reactions
- Neural Networks and Applications
- Planarian Biology and Electrostimulation
- Global trade and economics
- Diversity and Career in Medicine
- Insect behavior and control techniques
- Olfactory and Sensory Function Studies
University of Washington
2011-2025
Virginia Tech
2022-2025
Guru Teg Bahadur Hospital
2020
Seattle University
2020
Jawaharlal Nehru Medical College
2015
Abstract Animals rely on sensory cues to classify objects in their environment and respond appropriately. However, the spatial structure of those can greatly impact when, where, how they are perceived. In this study, we examined relative roles visual chemosensory mate recognition behavior fruit flies (Drosophila melanogaster) by using a robotic fly dummy that was programmed interact with individual males. By pairing male dummies various shapes, sizes, speeds, or coated different pheromones,...
Proprioception, the sense of self-movement and position, is mediated by mechanosensory neurons that detect diverse features body kinematics. Although proprioceptive feedback crucial for accurate motor control, little known about how downstream circuits transform limb sensory information to guide output. Here we investigate neural in Drosophila process from fly leg. We identify three cell types distinct developmental lineages are positioned receive input proprioceptor subtypes encoding tibia...
Summary Like the vertebrate spinal cord, insect ventral nerve cord (VNC) mediates limb sensation and motor control. Here, we apply automated tools for electron microscopy volume alignment, neuron segmentation, synapse prediction toward creating a connectome of an adult female Drosophila VNC. To interpret connectome, it is crucial to know its relationship with rest body. We therefore mapped muscle targets leg wing neurons in by comparing their morphology genetic driver lines, dye fills, X-ray...
Animal movement is controlled by motor neurons (MNs), which project out of the central nervous system to activate muscles. MN activity coordinated complex premotor networks that allow individual muscles contribute many different behaviors. Here, we use connectomics analyze wiring logic circuits controlling Drosophila leg and wing. We find both cluster into modules link MNs innervating with related functions. Within most modules, synaptic weights each neuron are proportional size their target...
Controlling arms and legs requires feedback from proprioceptive sensory neurons that detect joint position movement. Proprioceptive must be tuned for different behavioral contexts, but the underlying circuit mechanisms remain poorly understood. Using calcium imaging in behaving
Abstract Somatosensory neurons provide the nervous system with information about mechanical forces originating inside and outside body. Here, we use connectomics from electron microscopy to reconstruct analyze neural circuits downstream of largest somatosensory organ in Drosophila leg, femoral chordotonal (FeCO). The FeCO has been proposed support both proprioceptive sensing fly’s femur-tibia joint exteroceptive substrate vibrations, but it was unknown which sensory central contribute each...
To effectively control their bodies, animals rely on feedback from proprioceptive mechanosensory neurons. In the Drosophila leg, different proprioceptor subtypes monitor joint position, movement direction, and vibration. Here, we investigate how these diverse sensory signals are integrated by central circuits. We find that for leg position directional converge in second-order neurons, revealing pathways local of posture. Distinct populations neurons integrate tibia vibration across pairs...
Abstract Somatosensory neurons provide the nervous system with information about mechanical forces originating inside and outside body. Here, we use connectomics from electron microscopy to reconstruct analyze neural circuits downstream of largest somatosensory organ in Drosophila leg, femoral chordotonal (FeCO). The FeCO has been proposed support both proprioceptive sensing fly’s femur-tibia joint exteroceptive substrate vibrations, but it was unknown which sensory central contribute each...
Many animals use visual cues such as object shape, color and motion to detect pursue conspecific mates. Contrast is another possibly informative cue, but has not been studied in great detail. In this study, we presented male Drosophila melanogaster with small, fly-sized, moving objects painted either black, white or gray test whether they contrast identify We found that males frequently chased rarely black objects. Although started chasing often objects, the resulting chases were much...
The last decade has seen dramatic increase in offshoring activities motivated by the drive to cut operation cost, focus on core competencies, speed market and stay globally competitive. emergence of internet as an enabling technology further accelerated pace activity. In this paper, we attempt study decision making. literature making largely taken a firm related view decisions. We argue that host country's characteristics also play important role determining consider level such environment...
Abstract Proprioception, the sense of self-movement and position, is mediated by mechanosensory neurons that detect diverse features body kinematics. Although proprioceptive feedback crucial for accurate motor control, little known about how downstream circuits transform limb sensory information to guide output. Here, we investigate neural in Drosophila process from fly leg. We identify three cell-types distinct developmental lineages are positioned receive input proprioceptor subtypes...
Abstract Crossed Testicular Ectopia (CTE)/Transverse (TTE) is a rare but well-known congenital anomaly, in which both gonads migrate toward the same hemiscrotum. It usually associated with other abnormalities such as persistent Mullerian duct syndrome, True Hermaphroditism, Inguinal Hernia, Hypospadias, Pseudohermaphroditism, and scrotal anomalies. We report case of 6 years old male child right undescended testis empty left scrotum. Diagnosis was confirmed preoperatively by ultrasound...
Abstract To effectively control their bodies, animals rely on feedback from proprioceptive mechanosensory neurons. In the Drosophila leg, different proprioceptor subtypes monitor joint position, movement direction, and vibration. Here, we investigate how these diverse sensory signals are integrated by central circuits. We find that for leg position directional converge in second-order neurons, revealing pathways local of posture. Distinct populations neurons integrate tibia vibration across...
Event Abstract Back to The use of a controllable fly robot explore object recognition and visual tracking during courtship in Drosophila Sweta Agrawal1* Michael Dickinson1 1 University Washington, Biology, United States Visual is essential for variety behaviors, from foraging prey capture courtship, has been studied many animals, including both invertebrates vertebrates. However, little known about the function fruit fly, melanogaster. While overall circuitry functioning system well studied,...
A major challenge in the practical use of Machine Translation (MT) is that users lack guidance to make informed decisions about when rely on outputs. Progress quality estimation research provides techniques automatically assess MT quality, but these have primarily been evaluated vitro by comparison against human judgments outside a specific context use. This paper evaluates feedback vivo with study simulating decision-making high-stakes medical settings. Using Emergency Department discharge...