A5001262275- Breast Cancer Treatment Studies
- Digital Radiography and Breast Imaging
- Breast Lesions and Carcinomas
- AI in cancer detection
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Medical Imaging Techniques and Applications
- Global Cancer Incidence and Screening
- Total Knee Arthroplasty Outcomes
- Breast Implant and Reconstruction
- Osteoarthritis Treatment and Mechanisms
- Ultrasound and Hyperthermia Applications
- Orthopedic Surgery and Rehabilitation
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Hip disorders and treatments
- Ultrasound Imaging and Elastography
- Cancer and Skin Lesions
- Knee injuries and reconstruction techniques
- Advanced X-ray and CT Imaging
- Dupuytren's Contracture and Treatments
- COVID-19 diagnosis using AI
- Musculoskeletal synovial abnormalities and treatments
- Teratomas and Epidermoid Cysts
- Reconstructive Surgery and Microvascular Techniques
King's College Hospital
2006-2024
Imperial College Healthcare NHS Trust
2012-2021
Charing Cross Hospital
2006-2021
King's College Hospital NHS Foundation Trust
2016-2021
St Mary's Hospital
2019
St. Mary's Hospital
2019
National Health Service
2019
Faculty of 1000 (United Kingdom)
2018
The University of Sydney
2018
Universidad de Londres
2018
Many papers have been published recently on the subject of pseudotumors surrounding metal-on-metal hip resurfacing and replacement prostheses. These are sterile, inflammatory lesions within periprosthetic tissues variously termed masses, cysts, bursae, collections, or aseptic lymphocyte-dominated vasculitis-associated (ALVAL). The prevalence in patients with a well-functioning prosthesis is not well known. purpose this study was to quantify adjacent painful prostheses, characterize these use...
The Efficacy of Axillary Ultrasound in the Detection Nodal Metastasis Breast CancerBelinda Lee1, Adrian K. Lim2, Jonathan Krell1, Keshthra Satchithananda2, R. Charles Coombes1, Jacqueline S. Lewis3 and Justin Stebbing1Audio Available | Share
Metal artifact reduction sequence (MARS) MRI and ultrasound scanning (USS) can both be used to detect pseudotumors, abductor muscle atrophy, tendinous pathology in patients with painful metal-on-metal (MOM) hip arthroplasty. We wanted determine the diagnostic test characteristics of USS using MARS as a reference for detection pseudotumors atrophy. PatienTS AND METHODS: performed prospective cohort study compare findings 19 consecutive unilateral MOM hips. Protocolized was by consultant...
To analyse digital breast tomosynthesis (DBT) reading times in the screening setting, compared to 2D full-field mammography (FFDM), and investigate impact of reader experience professional group on interpretation times.
Metal artifact reduction sequence (MARS) MRI is widely advocated for surveillance of metal-on-metal hip arthroplasties (MOM-HAs). However, its use limited by susceptibility at the prosthesis-bone interface, local availability, patient compliance, and cost (Hayter et al. 2011a). We wanted to determine whether CT a suitable substitute MARS in evaluation painful MOM-HA.50 MOM-HA patients (30 female) with unexplained prostheses underwent imaging. 2 observers who were blind regarding clinical...
Joint injury is a major risk factor for osteoarthritis and provides an opportunity to prospectively examine early processes associated with osteoarthritis. We investigated whether predefined baseline demographic clinical factors, protein analytes in knee synovial fluid plasma or serum, were clinically relevant outcomes at 2 years after injury.This longitudinal cohort study recruited individuals aged 16-50 between Nov 1, 2010, 28, 2014, across six hospitals clinics London, UK. Participants...
Objective: To compare the experience of four UK Centres in use intradermal microbubbles and contrast enhanced ultrasound (CEUS) to pre-operatively identify biopsy sentinel lymph nodes (SLN) patients with breast cancer. Methods: In all centres, cancer had a microbubble/CEUS SLN core prior axillary surgery 1 2 normal greyscale ultrasound. Data were collected between 2010 2016; 1361 from Centre (prospective, sequential), 376 (retrospective, 121 3 selected) 48 4 selected). Results: successfully...
The interpretation of digital breast tomosynthesis (DBT) screening examinations is a complex task for an already overstretched workforce which has the potential to increase pressure on readers leading fatigue and patient safety issues. Studies in non-medical medical settings have suggested that changes blink characteristics can reflect fatigue. purpose this study investigate use as objective marker interpreting DBT examinations.Twenty-six involved UK PROSPECTS trial interpreted test set 40...
Failure to place an artificial hip in the optimal center of rotation results poor function and costly complications. The aim this study was develop robust methodology estimate (hCoR) from preoperative computed tomography (CT) scans, using contralateral anatomy, patients with unilateral diseased hips. Ten (five male, five female) normal pelvic one patient a dysplastic acetabulum were recruited London Implant Retrieval image bank. 3D models each pelvis generated commercial software. Two...
Objective.DIP joint OA is common but has few cost-effective, evidence-based interventions.Pain and deformity [radial or ulnar deviation of the loss full extension (extension lag)] frequently lead to functional cosmetic issues.We investigated whether splinting DIP would improve pain, function deformity.Methods.A prospective, radiologist-blinded, non-randomized, internally controlled trial custom was carried out.Twenty-six subjects with painful, deforming hand gave written, informed...
This multicentre, retrospective study aimed to establish correlation between estimated tumour volume doubling times (TVDT) from a series of interval breast cancers with their clinicopathological features. The potential impact delayed diagnosis on prognosis was also explored.
Breast metastases from non-breast primaries are rare in female patients and exceedingly male patients, with only a handful of cases described. Lymphoma, metastatic melanoma bronchial carcinoma the primary sites for majority breast metastases. colorectal have been described previously small number literature. Here, we report further two biopsy-proven to both breasts, who demonstrate contrasting unusual atypical imaging features that not reported previously. In one case, appearances mimic...
Abstract: A prospective audit of 221 breast biopsies was carried out to assess the pain/discomfort experienced during image-guided biopsies. The only significant factor in pain scores size needle used. Fine-needle aspiration cytology using a 21-gauge found cause most discomfort.
Acute appendicitis presenting with scrotal symptoms is a rare event, occurring when patent processus vaginalis persists. We present case where ultrasound demonstrated an inflamed appendix and abscess, allowing the correct surgical management in difficult clinical situation. In child signs vague lower abdominal symptoms, assessment of right iliac fossa should always be performed.
Abstract Objectives Digital breast tomosynthesis (DBT) can improve diagnostic accuracy compared to 2D mammography, but DBT reporting is time-consuming and potentially more fatiguing. Changes in subjective objective fatigue were evaluated over a session, the impact of taking break was assessed. Materials methods Forty-five National Health Service (NHS) mammography readers from 6 hospitals read cancer-enriched set 40 cases whilst eye tracked this prospective cohort study, December 2020 April...
Objective The purpose of this study was to determine the normal range Doppler ultrasonographic measurements spermatic cord arteries in a cohort healthy men. Methods 51 men were interrogated with color ultrasonography. resistive index (RI) each artery measured for entire cohort; peak systolic and end-diastolic velocity values obtained smaller subgroup (n = 31). lowest RI labeled A; other 2 identified as B C. Results Three separate within all individuals. median A, B, C 0.70 (range,...
Objectives . Early change in rheumatoid arthritis (RA) is characterised by periarticular osteopenia. We investigated the relationship of early metacarpal digital X-ray radiogrammetry bone mineral density (DXR-BMD) rate (RC-BMD, mg/cm 2 /month) to longitudinal changes hand and feet radiographic wrist MRI scores over 1 year. Materials Methods 10 RA patients completed study had 3T-MRI X-rays at various time points was scored RAMRIS, done van der Heijde modified Sharp scoring, RC-BMD analysed...
Introduction:The aim was to compare the accuracy of standard supplementary views and GE digital breast tomosynthesis (DBT) for assessment soft tissue mammographic abnormalities.Methods: Women recalled further abnormalities were recruited received (typically spot compression views) two-view DBT.The added value DBT in process determined by analysing data collected prospectively unblinded radiologists working up cases.Following anonymisation cases, there also a retrospective multireader...
Introduction: This multicentre randomised controlled trial investigated whether a computed tomography (CT) scan of the axilla could more accurately assess axillary lymph nodes were involved with malignancy in patients newly diagnosed breast cancer and therefore influence surgical decision-making regard to surgery.Methods: Patients (via screening symptomatic routes) at two NHS Trusts North East England recruited equal numbers.Both groups received routine diagnostic care (usual care).In...