- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- HIV, Drug Use, Sexual Risk
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Diagnosis and treatment of tuberculosis
- Clostridium difficile and Clostridium perfringens research
- Respiratory viral infections research
- Amoebic Infections and Treatments
- Influenza Virus Research Studies
- Heavy Metal Exposure and Toxicity
- Viral Infections and Vectors
- Sex work and related issues
- Leptospirosis research and findings
- COVID-19 epidemiological studies
- Antifungal resistance and susceptibility
- Infection Control and Ventilation
- Animal Disease Management and Epidemiology
- Parasites and Host Interactions
- HIV Research and Treatment
- Viral Infections and Outbreaks Research
- Heavy metals in environment
Ministry of Health and Welfare
2011-2022
National Taiwan University
2008-2021
National Taiwan University Hospital
2006-2019
Centers for Disease Control and Prevention
2009-2013
Epidemic Intelligence Service
2010-2013
Missouri Department of Health and Senior Services
2011-2013
Florida Department of Health
2011
Hyattsville Community Development Corporation
2010
Bernhard Nocht Institute for Tropical Medicine
2000
Department of Health
1994
Mucormycosis is a fungal infection caused by environmentally acquired molds. We investigated cluster of cases cutaneous mucormycosis among persons injured during the May 22, 2011, tornado in Joplin, Missouri.We defined case as soft-tissue person tornado, with evidence mucormycete on culture or immunohistochemical testing plus DNA sequencing. conducted case-control study reviewing medical records and conducting interviews patients hospitalized controls. sequencing whole-genome were performed...
In May 2010, a team of national and international organizations was assembled to investigate children's deaths due lead poisoning in villages northwestern Nigeria.Our goal determine the cause childhood outbreak, risk factors for child mortality, identify children < 5 years age need emergency chelation therapy poisoning.We administered cross-sectional, door-to-door questionnaire two affected villages, collected blood from 2-59 months age, obtained soil samples family compounds. Descriptive...
During May-June 2010, a childhood lead poisoning outbreak related to gold ore processing was confirmed in two villages Zamfara State, Nigeria. June-September of that year, with suspected or continued be identified State.We investigated the extent [≥ 1 child blood level (BLL) ≥ 10 µg/dL] and contamination (≥ soil/dust sample > 400 parts per million) among State should prioritized for urgent interventions.We used chain-referral sampling identify interest, defined as participation during...
Background Sexually transmitted Entamoeba histolytica infection (EHI) has been increasingly recognized among men who have sex with (MSM). We used the National Disease Surveillance Systems (NDSS) to identify prevalent and incident HIV diagnoses adults EHI determine associated factors. Methodology The NDSS collect demographic, clinical, behavioral characteristics of case patients through physician reports public health interviews. was confirmed by polymerase-chain-reaction assays,...
In February 2015 an outbreak of gastroenteritis occurred in a distillery Kinmen, Taiwan. At least 450 affected employees developed the symptoms diarrhea and vomiting after attending lunch banquet on 6 February. Epidemiological, laboratory environmental investigations were conducted to identify agent source this outbreak. A case–control study was carried out among attendees from distillery. Using semi-structured questionnaire, food beverage consumption assessed, as well demographic clinical...
The Taiwan Centers for Disease Control (CDC) were notified of increasing acute hepatitis A (AHA) in June 2015. Serum and/or stool from AHA patients and sewage samples tested virus (HAV). We defined outbreak cases as with illness onset after 2015 an HAV sequence less than 0.5% different that the TA-15 strain. analysed characteristics food exposures between non-outbreak January 2014 (start enhanced surveillance) February 2016. From to September 2017, there 1,563 a median age 31 years...
Abstract In 2008, an outbreak of human trichinosis associated with ingestion raw soft-shelled turtles was identified and investigated in Taiwan. The data suggested that patients were likely infected Trichinella papuae.
We report an outbreak of azithromycin-nonsusceptible Shigella flexneri 3a infection in Taiwan associated with men who have sex men. The bacterial strains belonged to the sublineage A a recently reported lineage men, characterized by reduced azithromycin susceptibility and circulation shigellosis low-risk regions.
In Taiwan, around 1,500 cases of dengue fever are reported annually and incidence has been increasing over time. A national web-based Notifiable Diseases Surveillance System (NDSS) in operation since 1997 to monitor trends support case outbreak management. We present the findings an evaluation NDSS ascertain extent which surveillance objectives being achieved.We extracted data on all laboratory-confirmed during 1 January 2010 31 December 2012 assess describe key system attributes based...
Outbreaks of hepatitis A virus (HAV) infection have been occurring among men who sex with in the Asia-Pacific region, United States, and several European countries since June 2015 recently persons are homeless use illicit drugs States. We evaluated serologic responses effectiveness HAV vaccination human immunodeficiency (HIV)-positive individuals during outbreak Taiwan. From 1, 2015, to September 30, 2016, anti-HAV immunoglobulin G was prospectively determined all HIV-positive individuals....
Objectives Outbreaks of shigellosis among men who have sex with (MSM) been reported since the late 1990s. HIV infection is an important risk factor. Since 2014, global epidemic has intensified. Whether chemsex (the use crystal methamphetamine, γ-hydroxybutyrate or mephedrone to enhance sex) a new factor not previously examined. Methods We conducted population-based, case–control study in Taiwan. Acute cases diagnosed during 2015 outbreak MSM living were compared those without shigellosis....
Summary Background Data are limited regarding the effectiveness and safety of generic velpatasvir plus sofosbuvir ( VEL / SOF ) for hepatitis C virus HCV in patients with or without human immunodeficiency HIV coinfection. Aim To evaluate ‐based therapy infection coinfection Taiwan. Methods Sixty‐nine ‐coinfected 159 ‐monoinfected receiving 12 weeks ribavirin RBV were prospectively enrolled. The anti‐viral responses adverse events AE s) compared between two groups. characteristics potentially...
Abstract Background Data on hepatitis C virus (HCV) reinfection in East Asian people with HIV after treatment-induced sustained virologic response (SVR) are limited. Methods HIV/HCV-coinfected patients Taiwan who achieved SVR12 interferon (IFN) or direct-acting antivirals (DAAs) between 2005 and 2021 underwent HCV RNA measurements at SVR24 then biannually. was defined as the detection of different strains beyond SVR12. HIV-negative, low-risk individuals served reference patients. Crude rates...
Risk of pneumocystosis after discontinuation primary or secondary prophylaxis among HIV-infected patients before CD4 counts increase to >==200 cells/microL (early discontinuation) receiving highly active antiretroviral therapy (HAART) is rarely investigated.Medical records 660 with baseline <200 who sought HIV care and received HAART at a university hospital in Taiwan between 1 April, 1997 30 September, 2007 were reviewed assess the incidence rate for pneumocystosis.The was 2.81 per 100...
Bronchiolitis obliterans, an irreversible lung disease, was first associated with inhalation of butter flavorings (diacetyl) in workers at a microwave popcorn company. Excess rates lung-function abnormalities were related to cumulative diacetyl exposure. Because information on potential excess mortality would support development permissible exposure limits for diacetyl, we investigated respiratory-associated during 2000-2011 among current and former this company who had participated...
Abstract Background Beginning from 2015–2016, unprecedented large outbreaks of acute hepatitis A that predominantly affected men who have sex with (MSM) reemerged across the continents. We assessed impact an early initiated virus (HAV) vaccination campaign targeted MSM living human immunodeficiency (HIV) during 2015–2017 outbreak in Taiwan. Methods First, we ascertained effectiveness HAV for HIV using a nested case-control study 1470 persons were initially HAV-seronegative. then fitted model...
Journal Article Disseminated Penicillium marneffei infection in an African AIDS patient Get access Y. Lo, Lo ∗ 1Department of Medicine Bernhard-Nocht Institut Tropical Medicine, Bernhard-Nocht-Str. 74, 20359 Hamburg, Germany ∗Address for correspondence: Dr Y.-R. c/o WHO Office Thailand, Ministry Public Health, Tiwanond Road, Nonthaburi 11 000, Thailand; phone +66 2 5903 218, fax 5918 199. yingrulo@whothai.moph.go.th Search other works by this author on: Oxford Academic PubMed Google Scholar...
New human immunodeficiency virus (HIV) diagnoses in the St. Louis metropolitan area, MO, occur predominantly among men who have sex with (MSM). The Centers for Disease Control and Prevention recommends HIV testing at least annually sexually active MSM. We examined prevalence factors associated recent MSM area.The 2008 National Behavioral Surveillance system recruited 21 US areas through venue-based, time-space sampling. Men were interviewed behavioral risks history. analysis included had...
Summary In Taiwan, an outbreak of acute hepatitis A ( AHA ) infection has been identified since June 2015. Approximately half the cases occurred in HIV ‐infected men who have sex with MSM ). We used Taiwan Centers for Disease Control TCDC )‐operated National Surveillance Systems NDSS to identify incidence during 2011‐2016. Between 2015 and December 2016, a total 1268 were documented, 601 (47.4%) co‐infected ; majority whom (98.4%). Each case was matched two controls without reported on age...
The use of condoms is an aid to protection against human immunodeficiency virus (HIV) infection and other sexually transmitted diseases (STDs). In a one-and-a-half month period in mid-1993, 190 commercial female sex workers 633 male clients 8 Social Hygiene Clinics Hong Kong were interviewed on their practice condom usage. For both clients, 18.5% 22.8% never 55.3% 50.3% seldom used during sexual contacts with paying partners non-paying respectively. majority (86%) claimed that they would if...