A5082554915- Microbial Community Ecology and Physiology
- Polar Research and Ecology
- Soil Carbon and Nitrogen Dynamics
- Lung Cancer Diagnosis and Treatment
- Gut microbiota and health
- Antenna Design and Analysis
- Protist diversity and phylogeny
- Lung Cancer Treatments and Mutations
- Advanced Antenna and Metasurface Technologies
- Geology and Paleoclimatology Research
- Dental Implant Techniques and Outcomes
- Genomics and Phylogenetic Studies
- Advanced Radiotherapy Techniques
- Orthodontics and Dentofacial Orthopedics
- Management of metastatic bone disease
- Climate change and permafrost
- Methane Hydrates and Related Phenomena
- Dental Radiography and Imaging
- Metamaterials and Metasurfaces Applications
- Head and Neck Cancer Studies
- Biocrusts and Microbial Ecology
- Marine and coastal ecosystems
- Microwave Engineering and Waveguides
- Colorectal Cancer Screening and Detection
- Periodontal Regeneration and Treatments
Queen's University
2012-2025
Institute of Tibetan Plateau Research
2016-2025
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2018-2024
Capital Normal University
2023-2024
Harbin Institute of Technology
2014-2024
Hebei Semiconductor Research Institute
2024
Nanjing Drum Tower Hospital
2021-2024
Center for Excellence in Tibetan Plateau Earth Sciences
2019-2022
Tianjin Academy of Agricultural Sciences
2022
Abstract Background Antarctica and its unique biodiversity are increasingly at risk from the effects of global climate change other human influences. A significant recent element underpinning strategies for Antarctic conservation has been development a system Conservation Biogeographic Regions (ACBRs). The datasets supporting this classification are, however, dominated by eukaryotic taxa, with contributions bacterial domain restricted to Actinomycetota Cyanobacteriota. Nevertheless, ice-free...
Summary Rare biosphere represents the majority of Earth's biodiversity and performs vital ecological functions, yet little is known about its biogeographical patterns community assembly processes in terrestrial ecosystems. Herein, we investigated composition phylogeny rare (relative abundance <0.1%) abundant (>1%) bacteria dryland grassland soils on Tibetan Plateau. Results revealed similar at both compositional phylogenetic levels, but subcommunity was more heavily influenced by...
Biological soil crusts (BSCs) are common and play critical roles in semi‐arid arid ecosystems. Bacteria, as an important community BSCs, biochemical processes. However, how bacterial diversity change different successional stages of BSCs is still unknown. We used 454 pyrosequencing 16S rRNA to investigate the composition community, relationships between environmental factors were also explored. In number bacteria operational taxonomic units (OTUs) detected each sample ranged from 2572 3157....
ABSTRACT Salinity is one of the most important environmental factors influencing bacterial plankton communities in lake waters, while its influence on interactions has been less explored. Here, we investigated salinity diversity, and community structure Tibetan Plateau lakes. Our results revealed that saline lakes (salinity between 0.5 50 g/L) harboured similar or even higher diversity compared with freshwater (&lt; g/L), hyper-saline (&gt; exhibited lowest diversity. Network...
The composition of the gastrointestinal microbiome is increasingly recognized as a crucial contributor to immune and metabolic homeostasis—deficiencies in which are characteristic cystic fibrosis (CF) patients. murine model (CFTR−/−, CF), has, previous studies, demonstrated CF (GI) manifestations including slowed transit significant upregulation genes associated with inflammation. To determine if characteristics these phenotypes we used phylogenetic microarray compare small intestine...
BACKGROUND Practice guidelines recommend neoadjuvant chemotherapy (NACT) for bladder cancer. However, the evidence in support of adjuvant (ACT) is less robust. Here we describe whether efficacy NACT/ACT was sufficient to change clinical practice and demonstrated trials translated into effectiveness general population. METHODS Electronic records treatment were linked population‐based Ontario Cancer Registry identify all patients with cancer treated cystectomy 1994‐2008. Utilization compared...
Non-small-cell lung cancer (NSCLC) is predominantly a disease of the elderly. Retrospective analyses National Cancer Institute Canada Clinical Trials Group JBR.10 trial and Lung Adjuvant Cisplatin Evaluation (LACE) meta-analysis suggest that elderly benefit from adjuvant chemotherapy. However, were under-represented in these studies, raising concerns regarding reproducibility study results clinical practice.By using Ontario Registry, we identified 6,304 patients with NSCLC who treated...
Cold desert soil microbiomes thrive despite severe moisture and nutrient limitations. In Eastern Antarctic soils, bacterial primary production is supported by trace gas oxidation the light-independent RuBisCO form IE. This study aims to determine if atmospheric chemosynthesis widespread within Antarctic, Arctic Tibetan cold deserts, identify breadth of chemosynthetic taxa further characterize genetic determinants this process. H2 was ubiquitous, far exceeding rates reported fulfill...
ABSTRACT The autotrophic communities in the lakes of McMurdo Dry Valleys, Antarctica, have generated interest since early 1960s owing to low light transmission through permanent ice covers, a strongly bimodal seasonal cycle, constant cold water temperatures, and geographical isolation. Previous work has shown that carbon fixation these provides an important source organic matter this polar desert. Lake Bonney two lobes separated by shallow sill is one several chemically stratified dry...
Pseudomonas aeruginosa (PA) forms biofilms in lungs of cystic fibrosis (CF) patients, a process regulated by quorum-sensing molecules including N-(3-oxododecanoyl)-l-homoserine lactone (C12). C12 (10-100 µM) rapidly triggered events commonly associated with the intrinsic apoptotic pathway JME (CF ΔF508CFTR, nasal surface) epithelial cells: depolarization mitochondrial (mito) membrane potential (Δψ(mito)) and release cytochrome C (cytoC) from mitos into cytosol activation caspases 3/7, 8 9....
Global warming has resulted in substantial glacier retreats high-elevation areas, exposing deglaciated soils to harsh environmental conditions. Autotrophic microbes are pioneering colonizers the and provide nutrients extreme ecosystem devoid of vegetation. However, autotrophic communities remain less studied soils. We explored diversity succession cbbL gene encoding large subunit form I RubisCO, a key CO2-fixing enzyme, using molecular methods along 10-year deglaciation chronosequence on...