A5022740674- Muscle Physiology and Disorders
- Cell Adhesion Molecules Research
- Orthopedic Infections and Treatments
- T-cell and Retrovirus Studies
- Infectious Diseases and Tuberculosis
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Insect and Pesticide Research
- Cell death mechanisms and regulation
- Inflammatory Myopathies and Dermatomyositis
- Streptococcal Infections and Treatments
- Autoimmune and Inflammatory Disorders
- Sexual Differentiation and Disorders
- Gestational Diabetes Research and Management
- Microencapsulation and Drying Processes
- Dermatological and COVID-19 studies
- Connective tissue disorders research
- Potassium and Related Disorders
- Spine and Intervertebral Disc Pathology
- Birth, Development, and Health
- Infective Endocarditis Diagnosis and Management
- Advanced Drug Delivery Systems
- Protease and Inhibitor Mechanisms
- Social and Political Issues
- Insect Resistance and Genetics
Polytechnic Institute of Porto
2024-2025
Uningá - Centro Universitário Ingá
2024
Hospital Braga
2020-2024
University of Minho
2023-2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2023-2024
Instituto Nacional de Investigação Agrária e Veterinária
2024
Clinical Academic Center of Braga
2022
Universidade de São Paulo
2004-2013
Universidade de Ribeirão Preto
2009
Muscle degenerative diseases such as Duchenne Muscular Dystrophy are incurable and treatment options still restrained. Understanding the mechanisms factors responsible for muscle degeneration regeneration will facilitate development of novel therapeutics. Several recent studies have demonstrated that Galectin-1 (Gal-1), a carbohydrate-binding protein, induces myoblast differentiation fusion in vitro, suggesting potential role this mammalian lectin regenerative processes vivo. However,...
Vulvovaginal candidiasis (VVC) is characterized as a very common fungal infection that significantly affects women's health worldwide. Essential oils (EOs) are currently being evaluated an alternative therapy. The development of efficient techniques such micro- or nanoencapsulation for protecting and controlling release essential to overcome the limitations EO applications. Therefore, aim this study was develop characterize oregano EO-loaded keratin microparticles (OEO-KMPs) potential...
The ongoing efforts to sequence the honey bee genome require additional initiatives define its transcriptome. Towards this end, we employed Open Reading frame ESTs (ORESTES) strategy generate profiles for life cycle of Apis mellifera workers.
Previous studies proposed that myosin-Va regulates apoptosis by sequestering pro-apoptotic Bmf to the actin cytoskeleton through dynein light chain-2 (DLC2). Adhesion loss or other cytoskeletal perturbations would unleash Bmf, allowing it bind and inhibit pro-survival Bcl2 proteins. Here, we demonstrated overexpression of a medial tail fragment (MVaf) harboring binding site for DLC2 dramatically decreased melanoma cell viability. Morphological molecular changes, including surface blebbing,...
Abstract Background The sequencing of the D.melanogaster genome revealed an unexpected small number genes (~ 14,000) indicating that mechanisms acting on generation transcript diversity must have played a major role in evolution complex metazoans. Among most extensively used accounts for this is alternative splicing. It estimated over 40% Drosophila protein-coding contain one or more exons. A recent transcription map embryogenesis indicates 30% transcribed regions are unannotated, and 1/3 as...
Objectives: Insulin resistance (IR) affects children and adolescents with obesity early diagnosis is crucial to prevent long-term consequences. Our aim was identify predictors of IR develop a multivariate model accurately predict IR. Methods: We conducted cross-sectional analysis demographical, clinical, biochemical data from cohort patients attending specialized Paediatric Nutrition Unit in Portugal over 20-year period. developed regression models The participants were randomly divided into...
A previously healthy 3-year-old boy presented to the ED in May 2022 with pain and functional impairment of left upper limb following a fall previous day. The patient developed fever while ED, peak temperature 39°C noted during initial physical examination. His examination revealed limited movement shoulder, no skin lesions. Vital signs included 39°C, heart rate 115 bpm, respiratory 20 breaths per minute, blood pressure 98/53 mmHg oxygen saturation 100% on room air. Initial diagnostic...
To the Editors: Rhabdomyolysis is a syndrome caused by muscular necrosis with release of myoglobin, electrolytes, and other sarcoplasmic elements (ie, lactate dehydrogenase, creatine kinase, alanine aminotransferase aspartate aminotransferase) in bloodstream.1 In pediatric population, it associated different etiologies, especially infections, toxins, drugs, metabolic disorders, electrolyte disorders trauma. Nonetheless, viruses are most common cause infection. Clinically, children...
To the Editors: Although varicella usually runs a benign course, complications may rarely occur. We report case of previously healthy 6-year-old boy who presented to emergency department with persistent fever for last 5 days. Six days before admission, rash appeared, first on his chest and abdomen later legs, arms face. He was diagnosed chickenpox by primary care physician started oral acyclovir. On physical examination revealed presence erythematous papules, vesicular crusted lesions...