A5019637763- Oral Health Pathology and Treatment
- Dental Health and Care Utilization
- Cancer, Hypoxia, and Metabolism
- Liver physiology and pathology
- Oral microbiology and periodontitis research
- Oral and Maxillofacial Pathology
- Dental Erosion and Treatment
- Angiogenesis and VEGF in Cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Glycosylation and Glycoproteins Research
- Autoimmune Bullous Skin Diseases
- Pancreatic function and diabetes
- Liver Disease Diagnosis and Treatment
- Healthcare professionals’ stress and burnout
- High Altitude and Hypoxia
- Allergic Rhinitis and Sensitization
- Chemokine receptors and signaling
- Oropharyngeal Anatomy and Pathologies
- Urticaria and Related Conditions
- Malaria Research and Control
- Sarcoidosis and Beryllium Toxicity Research
- Cancer-related Molecular Pathways
- Cerebral Venous Sinus Thrombosis
- Genital Health and Disease
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Medical University of Lodz
2007-2024
Ehime University
2004-2009
The support mechanisms that are involved in lymph-node metastasis of oral squamous cell carcinoma (OSCC) remain largely unknown. Recent studies have demonstrated tumor cells express chemokine receptors and use chemokines to metastasize the target organ many malignancies humans. In this study, we examined expression function their OSCC. was assessed eight OSCC lines. CXCR3 mRNA protein were expressed all lines examined, while CXCR4 only HSC2, HSC3, Ca9-22 cells. Treatment with ligand for...
Cigarette smoking is related to many pathological conditions; however, chemical substances affect the oral cavity first, so it important consider its influence on mucosa and potentially pre-malignant lesions. The aim of this study was investigate effect microvessel density in lichen planus. Special emphasis placed examining relationship between expression c-Met receptor blood vessels habits.This included 34 patients with planus diagnosed clinically verified by histopathological examination...
Oral lichen planus (OLP) is a common chronic, T-cell-mediated, inflammatory and non-infectious mucodermatosis. Patients diagnosed with oral are more prone to depression, anxiety higher perceived mental stress than the rest of population.This study investigated control methods as means reducing pain levels in patients planus.The involved 62 adult who have never received any OLP treatment before. high level received, addition standard pharmacological treatment, herbal sedative medication or...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Dominiak M, Kłosek S, Gerlicz-Kowalczuk Z, Krzysiek J, Kobusiewicz A, Kaszuba A. Bullous pemphigoid resembling erythema gyratum repens – case report. Dermatology Review/Przegląd Dermatologiczny. 2017;104(4):439-445. doi:10.5114/dr.2017.69769. APA Dominiak, M., Kłosek, S., Gerlicz-Kowalczuk, Z., Krzysiek, J., Kobusiewicz, A., & Kaszuba, (2017). Dermatologiczny, 104(4), 439-445....
Abstract The article delves into the potential of probiotics and synbiotics as alternative approaches to preventing treating dental caries. Probiotics are live, nonpathogenic microorganisms combined with non living substances (prebiotics) that support their growth activity. Probiotics, including strains Lactobacilli, Bifidobacterium, Streptococcus, secrete various compounds, such antimicrobial substances, bacteriocins, enzymes, which help combat cariogenic bacteria. Research suggests...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Szymczak-Paluch M, Kłosek S. Is lichen planus-associated desquamative gingivitis associated with chronic comorbidities?. Dermatology Review/Przegląd Dermatologiczny. 2020;107(2):159-165. doi:10.5114/dr.2020.96359. APA Szymczak-Paluch, M., & Kłosek, (2020). Dermatologiczny, 107(2), 159-165. https://doi.org/10.5114/dr.2020.96359 Chicago Michalina L., and Sebastian K. Kłosek. 2020. "Is comorbidities?"....
Abstract Background Depression is a common disorder among older adults, yet it not standard element of the aging process. can affect oral health as result neglecting hygiene routines, poor nutrition, and avoiding necessary dental care, resulting in an increased risk caries periodontal disease. On other hand, general deteriorating with age also are without their impact on mental state. Objectives The aim this study was to assess prevalence depression its association problems patients over 65...
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease that significantly impacts everyday life. To date, little known about oral cavity health in patients with IPF. Aim The study aimed to evaluate the condition of IPF and assess their quality life concerning health. Methods was cross-sectional one, collecting clinical data control subjects without disorders. Data collection included baseline characteristics, inspection results, 12 answers provided...
サイクリン依存性キナーゼ（CDK）は細胞周期制御に重要な役割を果たしており，口腔癌を始め多くの癌でその異常が報告されている。CDK特異的阻害剤であるFlavopiridolはCDK1/2/4/7活性を特異的に阻害し，アポトーシスを誘導して口腔癌細胞株の増殖を抑制する。今回我々は，口腔癌細胞株における放射線とFlavopiridolの併用効果について検討した。Flavopiridolと放射線照射（4Gy）の併用により，口腔癌細胞株における増殖抑制効果は増強した。口腔癌細胞株をヌードマウスに移植したxenograftの検討においても，Flavopiridolと放射線照射の併用は相乗的な抗腫瘍効果を示した。以上の結果より，口腔癌に対する新たな治療戦略として有用である可能性が示唆された。