A5007877359- Gut microbiota and health
- Epigenetics and DNA Methylation
- Animal Nutrition and Physiology
- Autophagy in Disease and Therapy
- Diet and metabolism studies
- RNA modifications and cancer
- Endoplasmic Reticulum Stress and Disease
- Adipose Tissue and Metabolism
- Birth, Development, and Health
- Probiotics and Fermented Foods
- Aquaculture Nutrition and Growth
- Cancer-related gene regulation
- Amino Acid Enzymes and Metabolism
- Barrier Structure and Function Studies
- Polyamine Metabolism and Applications
- Clinical Nutrition and Gastroenterology
- Genomics, phytochemicals, and oxidative stress
- Muscle metabolism and nutrition
- Biochemical effects in animals
- Diet, Metabolism, and Disease
- Aquaculture disease management and microbiota
- Peroxisome Proliferator-Activated Receptors
- Cancer, Hypoxia, and Metabolism
- Immune Response and Inflammation
- Connexins and lens biology
China Agricultural University
2016-2025
Beijing Advanced Sciences and Innovation Center
2025
Jinan University
2024
Agency for Science, Technology and Research
2009-2023
China University of Mining and Technology
2023
Genome Institute of Singapore
2009-2023
State Key Laboratory of Animal Nutrition
2013-2023
Feed Research Institute
2023
State Grid Corporation of China (China)
2023
Chinese Medical Doctor Association
2020
l-Tryptophan (Trp) is known to play an important role in the health of large intestine. However, a dietary Trp small-intestinal mucosal barrier and microbiota remains poorly understood. The present study was conducted with weaned piglets address this issue. Postweaning were fed for 4 weeks corn- soybean meal-based diet supplemented 0 (Control), 0.1, 0.2, or 0.4% Trp. serum amino acids analyzed by bacterial 16S rRNA gene-based high-throughput sequencing methods high-performance liquid...
The Rb–E2F pathway drives cell cycle progression and proliferation, the molecular strategies safeguarding its activity are not fully understood. Here we report that E2F1 directly transactivates miR-449a/b . targets inhibits oncogenic CDK6 CDC25A , resulting in pRb dephosphorylation arrest at G1 phase, revealing a negative feedback regulation of pRb–E2F1 pathway. Moreover, miR-449 a/b expression cancer cells is epigenetically repressed through histone H3 Lys27 trimethylation, epigenetic drug...
Protein is quantitatively the most expensive nutrient in swine diets. Hence it imperative to understand physiological roles played by amino acids growth, development, lactation, reproduction, and health of pigs improve their protein nutrition reduce costs pork production. Due incomplete knowledge acid biochemistry nutrition, was traditionally assumed that neonatal, post-weaning, growing-finishing, gestating could synthesize sufficient amounts all "nutritionally nonessential acids" (NEAA)...