Gang Lin

ORCID: 0000-0002-6604-8512
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About
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Research Areas
  • interferon and immune responses
  • Aquaculture disease management and microbiota
  • Cytokine Signaling Pathways and Interactions
  • Immune Response and Inflammation
  • RNA regulation and disease
  • Birth, Development, and Health
  • Invertebrate Immune Response Mechanisms
  • Autophagy in Disease and Therapy
  • Viral Infections and Vectors
  • Infant Nutrition and Health
  • RNA and protein synthesis mechanisms
  • Metabolism, Diabetes, and Cancer
  • Cancer-related molecular mechanisms research
  • Cardiac Arrhythmias and Treatments
  • Helicobacter pylori-related gastroenterology studies
  • Reproductive Biology and Fertility
  • MicroRNA in disease regulation
  • Fatty Acid Research and Health
  • Sperm and Testicular Function
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Cardiac electrophysiology and arrhythmias
  • Histone Deacetylase Inhibitors Research
  • Calpain Protease Function and Regulation
  • NF-κB Signaling Pathways
  • Tannin, Tannase and Anticancer Activities

Nanchang University
2012-2021

Wuxi Third People's Hospital
2018

Second Affiliated Hospital of Nantong University
2017

China Agricultural University
2009-2017

Nantong University
2014-2017

Affiliated Hospital of Nantong University
2017

Soochow University
2015

First Affiliated Hospital of Soochow University
2015

Mitchell Institute
2014

Texas A&M University
2009-2014

Efficiency of nutrient utilization is reduced in neonates with intrauterine growth restriction (IUGR) compared those a normal birth weight (NBW). However, the underlying mechanisms are largely unknown. In this study, we applied temporal proteomic approach, coupled histological and biochemical analyses, to study dynamic changes proteome small intestinal mucosa IUGR piglets during nursing period (Days 1, 7 21). We identified 56 differentially expressed protein spots between NBW piglets. These...

10.1021/pr900747d article EN Journal of Proteome Research 2009-11-27

Tssk4 belongs to the Testis Specific Serine/threonine protein Kinase (TSSK) family, members of which play an important role in spermatogenesis and/or spermiogenesis. Several Tssk family proteins have extensively been studied. However, exact function remains unclear. A knockout mouse model was generated and males were subfertile due seriously decreased sperm motility. The ultrastructure Tssk4(-/-)sperm tail is disorganized at midpiece-principal piece junction, leading a severe bend flagellum....

10.1093/molehr/gau097 article EN Molecular Human Reproduction 2014-10-31

// Koulong Zheng 1 , Qing Zhang Gang Lin Yefei Li Zhenqiang Sheng Jue Wang Liang Chen Hui-he Lu Department of Cardiology, The Second Affiliated Hospital Nantong University, Nantong, China Correspondence to: Lu, email: nantongluhuihe@163.com Keywords: ischemic heart diseases, oxygen glucose deprivation (OGD), myocardial cells, SC79, Akt Received: December 08, 2016      Accepted: January 11, 2017      Published: 21, 2017 ABSTRACT SC79 is a...

10.18632/oncotarget.14785 article EN Oncotarget 2017-01-21

IFN regulatory factor (IRF)3 is a central regulator for IFN-β expression in different types of pathogenic infections. Mammals have various sensors that are involved monitoring pathogen intrusions. These can trigger IRF3-mediated antiviral responses through pathways. Endoplasmic reticulum-associated proteins stimulator gene (STING) and zinc finger DHHC-type containing 1 (ZDHHC1) critical mediators IRF3 activation response to viral DNA In this study, grass carp STING ZDHHC1 were found some...

10.4049/jimmunol.1700750 article EN The Journal of Immunology 2017-10-19

An important characteristic of intrauterine growth restricted (IUGR) neonate is the impaired intestinal barrier function. With use a pig model, this study was conducted to identify responsible microRNA (miRNA) for damage in IUGR neonates through comparing miRNA profile and normal porcine investigate regulation mechanism. Compared with ones, we identified 83 upregulated 76 downregulated miRNAs jejunum pigs. Notably, associated profoundly increasesd miR-29 family decreased expression...

10.1152/ajpgi.00020.2017 article EN AJP Gastrointestinal and Liver Physiology 2017-03-10
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