A5064728641- Reproductive System and Pregnancy
- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Pregnancy and Medication Impact
- Ectopic Pregnancy Diagnosis and Management
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Renal Diseases and Glomerulopathies
- Blood disorders and treatments
- Endometriosis Research and Treatment
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune Bullous Skin Diseases
- Systemic Lupus Erythematosus Research
- Dermatology and Skin Diseases
- Nasal Surgery and Airway Studies
- Immunodeficiency and Autoimmune Disorders
- Diabetes and associated disorders
- Intramuscular injections and effects
- Maternal and fetal healthcare
- Reproductive Health and Contraception
- Maternal Mental Health During Pregnancy and Postpartum
- Complement system in diseases
- PI3K/AKT/mTOR signaling in cancer
McGill University Health Centre
2016-2024
McGill University
2014-2024
Montreal General Hospital
2018-2022
CARE Fertility
2018
Mount Sinai Hospital
2018
University of Toronto
2017-2018
Importance Fewer than 5% of patients labeled with a penicillin allergy are truly allergic. The standard care to remove the label in adults is specialized testing involving prick and intradermal skin followed by an oral challenge penicillin. Skin resource intensive, limits practice specialist-trained physicians, restricts global population who could undergo delabeling. Objective To determine whether direct noninferior low-risk allergy. Design, Setting, Participants This parallel, 2-arm,...
Objective. Tumor necrosis factor inhibitors (TNFi) are increasingly used in pregnancy but frequently withheld the second or third trimesters. We evaluated maternal and fetal outcomes of women who continued their TNFi throughout compared to interrupted during pregnancy. Methods. retrospectively analyzed seen clinic with rheumatoid arthritis (RA), psoriatic arthritis, juvenile idiopathic (JIA), ankylosing spondylitis, were exposed separated pregnancies into 2 groups based on level exposure...
Abstract The effectiveness of intravenous immunoglobulin (IVIg) for patients with unexplained recurrent implantation failure (uRIF) remains debated. We retrospectively analysed outcomes uRIF treated IVIg compared to a separate control cohort within our center (01/2014–12/2021). Primary included live birth, miscarriage, or transfer failure. documented side effects and maternal/fetal outcomes. Logistic regression analysis was used assess association exposure adjust confounders. study 143...
With ongoing COVID-19 vaccination schedules and the popularity of cosmetic fillers, it is important to examine record associated adverse reactions a more general audience health care professionals. Case reports exist in subspecialty journals outlining after SARS-CoV-2 infection vaccination. This one first cases published Canada, highlights priorities challenges faced by physicians assessing managing patients presenting with post vaccination.We present case 43 -year-old women delayed type 4...
Studies on complement activation have implicated a combination of the classical pathway (CP), lectin (LP), and alternative (AP) in triggering terminal (TP) for each common autoimmune glomerulonephritis (GN). Evaluating different pathways simultaneously may help identify whether one is preferentially activated and, consequently, which best to target disease.We followed 112 patients with focal segmental glomerular sclerosis (FSGS), membranous nephropathy (MN), IgA (IgAN), lupus nephritis (LN),...
Recurrent pregnancy loss (RPL) affects up to 4% of couples attempting conceive. RPL is unexplained in over 50% cases and no effective treatments exist. Due the immune system's pivotal role during implantation pregnancy, immune-mediated may be suspected immunomodulatory like intravenous immunoglobulin (IVIg) have been administered but remain controversial. The goal our study was evaluate center's 6 year-outcomes develop a framework for IVIg use RPL.Retrospective, single-center cohort study....
Objective There are few precise or recent estimates of the risk causes stillbirths in women with systemic lupus erythematosus (SLE). Thus, we undertook present study to examine mothers SLE versus those without SLE. Methods The Offspring Mothers Registry (OSLER) is a large population‐based cohort, identified through Quebec's health care databases (1989–2009), including all who had ≥1 hospitalization for delivery after diagnosis, and randomly selected control group matched age year delivery....
Background Oral immunotherapy (OIT) is an emerging treatment for cow’s milk protein (CMP) allergy in children. The mechanisms driving tolerance following OIT are not well understood. Regulatory T cells (T REG ) key inhibitors of allergic responses and promoters allergen-specific tolerance. In exploratory study, we sought to detect induction a cohort subjects undergoing OIT. Methods Pediatric patients with history reaction positive Skin Pick Test (SPT) and/or CMP-specific IgE >0.35 kU,...