A5087763708- Medical Imaging Techniques and Applications
- Thyroid Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Radiation Dose and Imaging
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Muscle metabolism and nutrition
- Advanced Radiotherapy Techniques
- Diet and metabolism studies
- Chronic Kidney Disease and Diabetes
- Thyroid and Parathyroid Surgery
- Radiation Therapy and Dosimetry
- Prostate Cancer Treatment and Research
- Neuroendocrine Tumor Research Advances
- Adipose Tissue and Metabolism
- Bone health and treatments
- Pancreatic and Hepatic Oncology Research
- Prostate Cancer Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Thyroid Disorders and Treatments
- Radioactive Decay and Measurement Techniques
- Advanced X-ray and CT Imaging
- Pediatric Urology and Nephrology Studies
- Advanced MRI Techniques and Applications
- Salivary Gland Tumors Diagnosis and Treatment
Universidade de São Paulo
2016-2025
Instituto do Câncer do Estado de São Paulo
2015-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2025
Nuclear Engineering Institute
2015-2024
Cancer Institute (WIA)
2015-2018
Fundação de Amparo à Pesquisa do Estado de São Paulo
2015
Hospital São Paulo
2015
Universidade Estadual Paulista (Unesp)
2015
Universidade Brasil
2005-2014
Indiana University School of Medicine
2014
Abstract Purpose Ultrasound-guided biopsy (US biopsy) with 10–12 cores has a suboptimal sensitivity for clinically significant prostate cancer (sigPCa). If US is negative, magnetic resonance imaging (MRI)–guided recommended, despite low specificity lesions score 3–5 on Prostate Imaging Reporting and Data System (PIRADS). Screening guidance using an modality high accuracy could reduce the number of unnecessary biopsies, reducing side effects. The aim this study was to assess performance...
Melatonin, a pineal hormone synthesized at night, is critical for the synchronization of circadian and seasonal rhythms, being key regulator energy metabolism in many animal species. Although studies humans are lacking, several reports, mainly on hibernating animals, demonstrated that melatonin supplementation short photoperiod increase brown adipose tissue (BAT) mass. The present proof-of-concept study first, to our knowledge, evaluate BAT patients with deficiency (radiotherapy or surgical...
To prospectively evaluate demographic, anthropometric and health-related quality of life (HRQoL) in pediatric patients with laboratory-confirmed coronavirus disease 2019 (COVID-19).
Background The aim of this study was to determine the effects creatine supplementation on kidney function in resistance-trained individuals ingesting a high-protein diet.Methods A randomized, double-blind, placebo-controlled trial performed. participants were randomly allocated receive either (20 g/d for 5 d followed by throughout trial) or placebo 12 weeks. All engaged resistance training and consumed diet (i.e., ≥ 1.2 g/Kg/d). Subjects assessed at baseline (Pre) after weeks (Post)....
Abstract Objectives To assess the performance and prognostic role of Immulite® TSI Elecsys® TRAb immunoassays in patients with Graves’ disease (GD) undergoing radioactive iodine (RAI) therapy. Methods Clinical laboratory data 188 (156 GD 32 toxic nodule goiter), RAI therapy between January 2018 2022 were prospectively collected over 12 months. Refractoriness was defined as persistent or recurrent hyperthyroidism six months post-RAI treatment without levothyroxine. Statistical analysis...
Purposes: To evaluate the dosimetric effect of outpatient radioiodine therapy for thyroid cancer in members a patient's family and their living environment, when using iodine-131 doses reaching 7.4 GBq. The following parameters were thus defined: (a) whole-body radiation to caregivers, (b) production contaminated solid waste, (c) potential surface contamination within patients' quarters. Methods: In total, 100 patients treated on an basis, taking into consideration acceptable conditions,...
We aimed to investigate whether creatine supplementation affects the measured glomerular filtration rate in postmenopausal women (age, 58 ± 3 years). Subjects were randomly assigned receive either (20 g·day(-1) for 1 week and 5 thereafter) or a placebo. Kidney function was assessed at baseline after 12 weeks. [(51)Cr]EDTA clearance remained unchanged (CR-PRE: 86.16 14.36 mL·min(-1) per 1.73 m(2), POST: 87.25 17.60 m(2); PL-PRE: 85.15 8.54 87.18 9.64 p = 0.81). Thus, we concluded that does...
Abstract Purpose Prostate-specific membrane antigen (PSMA)-targeted PET is increasingly used for staging prostate cancer (PCa) with high accuracy to detect significant PCa (sigPCa). [ 68 Ga]PSMA-11 PET/MRI-guided biopsy showed promising results but also persisting limitation of sampling error, due impaired image fusion. We aimed assess the possibility intraoperative quantification 18 F]PSMA-1007 PET/CT uptake in core biopsies as an instant confirmation accurate lesion sampling. Methods In...
Introduction Creatine supplementation has emerged as a promising non-pharmacological therapeutic strategy to counteract muscle dysfunction and low lean mass in variety of conditions, including pediatric rheumatic diseases. The objective this study was examine the efficacy safety creatine childhood systemic lupus erythematosus (C-SLE). Methods C-SLE patients with mild disease activity ( n = 15) received placebo or randomized fashion using crossover, double-blind, repeated-measures design....
To measure the potential radiation dose emitted by patients who have recently undergone diagnostic nuclear medicine procedures, in order to establish optimal safety measures for such procedures.We evaluated doses 175 adult whom technetium-99m, iodine-131, and fluorine-18 radionuclides were administered bone, kidney, heart, brain, whole-body scans, as measured with a detector. Those values served basis evaluating radiopharmaceutical clearance, well risk exposure of others radiation, depending...
It has been suggested that creatine supplementation is safe and effective for treating idiopathic inflammatory myopathies, but no pediatric study conducted to date. The objective of this was examine the efficacy safety in juvenile dermatomyositis (JDM) patients.In study, JDM patients received placebo or (0.1 g/kg/day) a randomized, crossover, double-blind design. Subjects were assessed at baseline after 12 weeks. primary outcome muscle function. Secondary outcomes included body composition,...
Positron-emission tomography/computed tomography (PET/CT) has improved cyst infection (CI) management in autosomal dominant polycystic kidney disease (ADPKD). The determinants of and/or liver involvement, however, remain uncertain. In this study, we evaluated clinical and imaging factors associated with CI (KCI) (LCI) ADPKD. A retrospective cohort study was performed hospital-admitted ADPKD patients suspected CI. Clinical, surgical data were analyzed. Features infected cysts by PET/CT. Total...
This study aimed to establish a concise method for determining diagnostic reference level (DRL) adult and pediatric nuclear medicine patients on the basis of procedures administered radioisotope as means controlling medical exposure.A screening was carried out in all Brazilian Nuclear Medicine Service (NMS) establishments support this by collecting average activities during rules applied adjust these according patient's age body mass. Percentile 75 used establishing DRL patients, with...
Nuclear medicine procedures that use 131I activity represent significant sources of potential absorbed dose to medical staff, volunteers, and the general public. The exposures are due principally from excreted retained activities in patients' bodies. In general, exposure rate decreases a simple exponential manner. average effective half-life found for all patients study reported here is 11.41 ± 0.02 h; this information may be used guidelines on management thyroid cancer therapy...
Methods currently employed to establish the etiology of congenital hypothyroidism include thyroid ultrasound and scintigraphic exams. Thyroglobulin is a protein almost exclusively secreted by tissue indirectly reflects amount follicular cells. Even though thyroglobulin easy measure, it has been not frequently used because discordant results distinguish mainly athyreosis ectopy (dysgenesis). Knowing differences in inheritance prognosis dysgenesis dyshormonogenesis, important define CH,...
Renal function is related to thyroid hormonal status, and glomerular filtration rate (GFR) seems be impaired in patients with hypothyroidism. The aim of this work was evaluate quantitatively the effect hypothyroidism on GFR using a (51)Cr-EDTA radioisotope assay.Twenty-eight without known renal disease or dysfunction who had been referred for radioiodine therapy (RIT) after total thyroidectomy were enrolled study divided into two groups. Group A underwent hormone withdrawal (THW) resulting...