A5075769494- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Atmospheric chemistry and aerosols
- Microwave and Dielectric Measurement Techniques
- Analytical chemistry methods development
- Atmospheric Ozone and Climate
- thermodynamics and calorimetric analyses
- Acoustic Wave Resonator Technologies
- Air Quality and Health Impacts
- Molecular Sensors and Ion Detection
- Chemical Thermodynamics and Molecular Structure
- Lipid Membrane Structure and Behavior
- Synthesis and Characterization of Heterocyclic Compounds
- Antibiotics Pharmacokinetics and Efficacy
- Microwave Engineering and Waveguides
- Crystallography and molecular interactions
- Toxic Organic Pollutants Impact
- Atmospheric aerosols and clouds
- Synthesis and biological activity
- DNA and Nucleic Acid Chemistry
- Indoor Air Quality and Microbial Exposure
- Biosensors and Analytical Detection
- Cardiac Ischemia and Reperfusion
- Electrostatics and Colloid Interactions
- Synthesis and Biological Evaluation
B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine
2013-2025
National Academy of Sciences of Ukraine
2014-2025
O.Ya. Usikov Institute for Radiophysics and Electronics
2021-2025
University of Antwerp
2002-2010
National Academy of Sciences
2010
Max Planck Institute for Biogeochemistry
2004
CSIRO Oceans and Atmosphere
2004
Commonwealth Scientific and Industrial Research Organisation
2004
Ghent University
2004
Universidade de São Paulo
2004
Detailed organic analysis of natural aerosols from the Amazonian rain forest showed considerable quantities previously unobserved polar compounds, which were identified as a mixture two diastereoisomeric 2-methyltetrols: 2-methylthreitol and 2-methylerythritol. These polyols, have isoprene skeleton, can be explained by OH radical-initiated photooxidation isoprene. They low vapor pressure, allowing them to condense onto preexisting particles. It is estimated that results in an annual global...
Abstract. The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, 2002 transition from dry to wet season, was investigated by a suite state-of-the-art analytical techniques. period most intense biomass burning characterized high concentrations submicron particles rich material and water-soluble organic compounds (WSOC). At onset rainy period, total carbon (TC) decreased about 20 times. In contrast, concentration...
Abstract We developed and validated a gas chromatographic/ion trap mass spectrometric method for the determination of levoglucosan related monosaccharide anhydrides, mannosan, galactosan 1,6‐anhydro‐β‐ D ‐glucofuranose in urban atmospheric aerosols collected on quartz fiber filters. The is based extraction with dichloromethane–methanol (80 : 20, v/v), trimethylsilylation, multiple reaction monitoring tandem mode using ion at m / z 217, use an internal standard calibration procedure...
Abstract. Measurements of polar organic marker compounds were performed on aerosols that collected at a pasture site in the Amazon basin (Rondônia, Brazil) using high-volume dichotomous sampler (HVDS) and Micro-Orifice Uniform Deposit Impactor (MOUDI) within framework 2002 LBA-SMOCC (Large-Scale Biosphere Atmosphere Experiment Amazônia – Smoke Aerosols, Clouds, Rainfall, Climate: Aerosols From Biomass Burning Perturb Global Regional Climate) campaign. The campaign spanned late dry season...
This study focuses on developing a metal-dielectric sensor structure with optimized unit cell geometry for the determination of protein Immunoglobulin G (IgG) concentration in aqueous solutions. The research combines both experimental and theoretical investigations, utilizing differential microwave dielectrometry method numerical modeling COMSOL software. Complex permittivity (CP) values dependence IgG water solutions was experimentally obtained at microwaves using dielectrometer setup...
This paper reports the results of numerical modeling wave reflection coefficient behavior metal-dielectric metasurface at microwaves that can be used for biomedical applications. The study includes optimization working parameters metasurface-based structure as a sensitive element microwave sensoring systems determination proteins concentration in different solutions. In current research unit with geometry, which is similar to geometry one well standard 96-multiwell laboratory microplate,...
In this study, we demonstrate, using electrospray ionization mass spectrometry (ESI-MS) and collision-induced dissociation tandem (ESI-MS/CID/MS), that stable noncovalent complexes can be formed between Fe(III)-heme antimalarial agents, i.e., quinine, artemisinin, the artemisinin derivatives, dihydroartemisinin, alpha- beta-artemether, beta-arteether. Differences in binding behavior of examined drugs with stability drug-heme are demonstrated. The results show all tested agents form a complex...
Qualitatively different membranotropic effects of the individual drugs and complexes formed in their combined use were demonstrated by differential scanning calorimetry.
Abstract Mechanisms of interaction between the antimicrobial drugs decamethoxinum and aethonium, which are based on bisquaternary ammonium compounds, a phospholipid component biological membranes, dipalmitoylphosphatidylcholine, were studied by means liquid secondary ion mass spectrometry (LSIMS) differential scanning calorimetry (DSC). Supramolecular complexes with this recorded under spectrometric conditions. The dependence structures these structural parameters dications compounds was...
Abstract In the course of a liquid secondary ion mass spectrometric (SIMS) investigation on bisquaternary ammonium antimicrobial agent, decamethoxinum, unusual pathways fragmentation organic dication M 2+ this salt, with preservation doubly charged state fragments, were observed. To reveal structural and electronic parameters which are responsible for stabilization its in gas phase, comprehensive SIMS study using metastable decay, collision‐induced dissociation kinetic energy release...
Abstract The effect of cone voltage (CV) variation on the mass spectral pattern bisquaternary ammonium salt decamethoxinum in electrospray ionization (ESI) mode was studied. advantage as a test compound ESI spectrometry lies production two types precursor ions, i.e. doubly charged organic dication Cat 2+ and its singly cluster with Cl − counterion, · + . This makes it possible to monitor fragmentation patterns these ions under identical experimental conditions. Pronounced qualitative...
Keywords: rhamnolipids, phospholipids, mass spectrometry, electrospray ionization (ESI), noncovalent complexes
Abstract The lyotropic L α-phase of hydrated dipalmitoylphosphatidylcholine has been proposed as a solvent medium for modeling the effects membranotropic agents upon cell membranes, including interactions between different inside membrane. For quasibinary systems containing bisquaternary ammonium compounds decamethoxinum or aethonium and 2,5-dihydroxybenzoic acid, calorimetry data allowed us to establish stoichiometry intermolecular complexes incorporated in interaction mechanisms have...
Abstract. The chemical composition of carbonaceous aerosols collected during the LBA-SMOCC field experiment, conducted in Rondônia, Brazil, 2002 transition from dry to wet season, was investigated by a suite advanced analytical techniques. period most intense biomass burning characterized high concentrations submicron particles rich material and water-soluble organic compounds (WSOC). At onset rainy period, total carbon (TC) had decreased about 20 times. In contrast, concentration...
Keywords: competitive complexation, bisquaternary ammonium compounds, aspirin, membrane phospholipids, mass spectrometry, electrospray ionization, possible activity modulation
Background: While antiviral and interferon-inducing agent tilorone is used as a reactant of number popular pharmacological preparations, the molecular mechanisms its biological activity are under discussions among specialists.That why level model studies interactions with targeting biomolecules their components considered to be urgent useful for understanding activity. Objectives:The current study devoted mechanistic examining intermolecular possible biomolecular targets which believed...
Enzymatic reactions are the basis of many biotechnological manufacturing and biomedical diagnostic procedures that require effective methods monitoring over reaction course. In current paper, we present results development a new approach within differential microwave dielectrometry method for non-invasive course enzymatic based on complex permittivity changes these reactive mixture solutions in real time at fixed frequency 31.82 GHz. The dynamic studies dielectric parameters selected systems...