A5024020719- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Neutropenia and Cancer Infections
- Urinary Tract Infections Management
- Nosocomial Infections in ICU
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Cardiac Arrest and Resuscitation
- Clinical practice guidelines implementation
- Pharmacological Effects and Toxicity Studies
- Renal and Vascular Pathologies
- Poisoning and overdose treatments
- Enterobacteriaceae and Cronobacter Research
- Pharmaceutical Practices and Patient Outcomes
- Palliative Care and End-of-Life Issues
- Healthcare Systems and Public Health
- Frailty in Older Adults
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- History of Medicine Studies
- Safe Handling of Antineoplastic Drugs
- COVID-19 and healthcare impacts
King Hussein Cancer Center
2019-2025
OBJECTIVES: To evaluate the effect of procalcitonin-guided management on duration antibiotic therapy in critically ill cancer patients with sepsis. DESIGN: Randomized, controlled, single-blinded trial. SETTING: A comprehensive multidisciplinary hospital Jordan. PATIENTS: Adults treated ICU who were started antibiotics for suspected infection, met SEPSIS-3 criteria, and expected to stay greater than or equal 48 hours. INTERVENTIONS: Patients randomized standard care (SC) arms. All had...
Infections impact morbidity and mortality in pediatric cancer patients, yet limited studies have assessed the microbiological profiles susceptibility patterns of pathogenic bacteria this population. This study aimed to investigate bacterial temporal resistance changes pediatrics with cancer. We identified positive cultures between January 2015 December 2022 for patients diagnosed at age < 18 years. Electronic records provided patient demographics, patterns. Using "R" programming, dataset was...
Urinary tract infections (UTIs) are among the most common community-acquired in patients with cancer. Though prevalence of multi-drug resistant organisms (MDROs) has increased, there limited studies on MDROs ambulatory cancer UTIs. Therefore, we aimed to evaluate and predictors this patient population.A retrospective study adult treated for bacterial UTIs setting at King Hussein Cancer Center. The medical laboratory's system was used identify positive urine cultures taken setting, between...
Abstract Augmented renal clearance (ARC) is a phenomenon that has been associated with enhanced excretion of renally eliminated drugs, such as antimicrobials, which may result in subtherapeutic levels and potentially therapeutic failure. There limited data on ARC critically ill patients cancer. This study aimed to evaluate the prevalence identify risk factors this patient population. was prospective at an oncologic intensive care unit (ICU) included adult normal function, defined serum...
Abstract The updated vancomycin guideline and recent studies suggested that trough concentrations may result in underestimation of the actual area under curve (AUC), leading to excessive dosing nephrotoxicity. With limited data available on critically ill cancer patients, this study aimed compare two methods patient population. This was a 5‐year retrospective patients treated with intensive care unit (ICU) comprehensive center. measured concentration compared Bayesian‐derived...
Background: Several antimicrobial stewardship interventions have demonstrated improved clinical outcomes. Though the impact of a pharmacist-led review cultures has been described, studies not evaluated such an intervention in institutions that primarily serve cancer patients. Aim: To describe pharmacist’s microbiological from adult patients ambulatory setting. Method: A retrospective study at comprehensive center included with positive treated setting, between August 2020 and February 2021....
Critical Care Medicine: January 2020 - Volume 48 Issue 1 p 681 doi: 10.1097/01.ccm.0000645548.71437.a9
Abstract This study tackled the issue of human trafficking and illegal immigration as stated in international agreements national legislation. Light was shed on Jordanian legislation subject this study. The aims at discussing concept immigration. problem arises from confusion between immigration, immigrant might be victim two crimes: smuggling. concluded that each these concepts has its own meaning. Despite fact they are different, confusing. researchers came up with a criterion by which...
Introduction: Concentrations taken at midpoint of a dosing interval may reflect both the volume distribution and clearance medications. We hypothesized that single vancomycin concentration obtained offer an alternative method to estimating area-under-the-curve (AUC) in cases where recommended Bayesian-based approach is not available. Our aim was compare accuracy precision AUC using concentrations, compared against two-level gold standard approach. Methods: This prospective study included...
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Nazer, Lama; Awad, Wedad; Thawabieh, Hadeel; Abusara, Aseel; Abdelrahman, Deema; Addassi, Awad; Abuatta, Osama; Sughayer, Maher; Shehabi, Yahya Author Information
Nazer, Lama; Awad, Wedad; Thawabieh, Hadeel; Abusara, Aseel; Abdelrahman, Deema; Addassi, Awad; Sughayer, Maher; Abuatta, Osama; Shehabi, Yahya Author Information
Introduction: Most patients with cancer receive their chemotherapy in the ambulatory setting. However, during cycles, they may develop adverse events requiring visits to Emergency Department (ED). We aimed apply a machine-learning model predict ED among on active chemotherapy. Such would help clinicians proactively identify who are at high risk for that necessitate visits, as well necessary resources. Methods: This was retrospective study included adult received cancer-related treatment...
Introduction: The workgroup in the most recent Surviving Sepsis Campaign (SSC) guidelines was considered more diverse, with women and better representation from low-income countries. However, diversity clinical studies supporting recommendations not described. Our objective to evaluate racial, sex, geographic evidence used derive infection-related recommendations, as well sex of authors. Methods: All cited support identified. Citations eligible for evaluation included meta-analysis while...