- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Gut microbiota and health
- Posttraumatic Stress Disorder Research
- Hemodynamic Monitoring and Therapy
- Gastrointestinal motility and disorders
- Cardiovascular and Diving-Related Complications
- Tryptophan and brain disorders
- Airway Management and Intubation Techniques
- Nausea and vomiting management
- Ultrasound in Clinical Applications
- Pancreatic and Hepatic Oncology Research
- Respiratory Support and Mechanisms
- Resilience and Mental Health
- Migration, Health and Trauma
- Disaster Response and Management
- Cancer, Hypoxia, and Metabolism
- Child and Adolescent Psychosocial and Emotional Development
- Clostridium difficile and Clostridium perfringens research
- Esophageal and GI Pathology
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Congenital gastrointestinal and neural anomalies
- Vascular Anomalies and Treatments
- Salivary Gland Disorders and Functions
Sichuan University
2014-2025
Zhongda Hospital Southeast University
2025
Nanjing Drum Tower Hospital
2018-2024
Beijing Tian Tan Hospital
2020-2021
Capital Medical University
2020-2021
Nanjing University
2019-2020
Weatherford College
2020
Suzhou University of Science and Technology
2019
Xinjiang Medical University
2019
Binzhou People's Hospital
2016-2018
To explore the status quo and influencing factors of residents' knowledge, attitude practice (KAP) in prevention control coronavirus disease 2019 (COVID-19), difficulties or challenges perceived by residents their preventive practice.
The development of a biodegradable and shape-adaptable bioscaffold that can enhance local cytokine retention bioactivity is essential for the application immunotherapy in periodontal diseases. Here, we report biodegradable, anti-inflammatory, osteogenic ILGel uses physically cross-linked DNA hydrogel as soft long-term sustained release interleukin-10 (IL-10) to accelerate diabetic alveolar bone rebuilding. Porous microstructures favored encapsulation IL-10 maintained at least 7 days. be...
Post-traumatic stress disorder is a common psychological maladaptation among adolescents after undergoing an earthquake. Knowledge about the prevalence and maintenance of post-traumatic symptoms changes its predictors over time can help medical providers assist adolescent survivors with mitigating long-term impacts. This study examined in posttraumatic relationship coping skill locus control earthquake China.The used observational longitudinal design. A total 1420 were evaluated twice by...
Abstract Background Serious and long-lasting psychiatric consequences can be found in children adolescents following earthquake, including the development of posttraumatic stress disorder (PTSD). Although researchers have been focused on PTSD recently, its prevalence risk factors after a huge natural disaster are still unclear because limited sample size. The purpose this study is to explore (PTSD) adolescent survivors three years Wenchuan describe symptoms, find out PTSD. Methods A total...
Novel waterborne polyurethane micelles with reactive groups on the surface has been prepared as a crosslinker and then reacted polyacrylamide (PAM) to obtain polyacrylamide–polyurethane/ionic liquid ionohydrogel for wireless strain sensors.
Pulmonary arterial hypertension is a fatal lung disease caused by the progressive remodeling of small pulmonary arteries (PAs). Sildenafil can prevent PAs, but conventional sildenafil formulations have shown limited treatment efficacy for their poor accumulation in PAs. Here, glucuronic acid (GlcA)-modified liposomes (GlcA-Lips) were developed to improve delivery aberrant over-proliferative PA smooth muscle cells via targeting GLUT-1 (glucose transport-1), and, therefore, inhibiting PAs...
The tumor suppressor ING4 has been shown to be reduced in human HCC.The alteration of contributes HCC progression.However, its effect and the potential mechanism is largely unclear.Herein, we found that downregulation tissues was closely associated with cancer staging, size vascular invasion.Lentivirus-mediated overexpression significantly inhibited proliferation, migration invasion, induced cell cycle G1 phase arrest apoptosis MHCC97H cells.Moreover, dramatically suppressed growth...
Objective: To investigate the key genetic mutations during progressive disease (PD) /leukemic transformation (LT) course in MDS by analyzing dynamic changes of patients with myelodysplastic neoplasms (MDS) or without PD/LT. Methods: This study enrolled 84 sequential from May 2019 to August 2023 at ZhongDa Hospital Southeast University and used next generation sequencing detect gene mutations. The PD/LT were retrospectively analyzed. Results: ①This analyzed data diagnosed a median age 63...
Background: The dopamine receptor D2 ( DRD2) and serotonin transporter 5-HTT) genes are associated with posttraumatic stress disorder (PTSD). However, it remains largely unknown whether these interact environmental factors to affect the development of PTSD. Purpose: purpose this study was examine associations gene polymorphisms gene–environment interactions risk developing PTSD among adolescent earthquake survivors. Method: A total 183 survivors from an earthquake-stricken area participated...
There is accumulating evidence indicating that the growth inhibitory effect of dichloroacetate (DCA) on pulmonary arterial smooth muscle cells (PASMCs) may be associated with reversal Warburg and initiation mitochondria‑dependent apoptotic pathway. Previous studies indicated platelet‑derived factor (PDGF) promoted resulted in resistance PASMCs, which was attributed to activation phosphatidylinositol 3‑kinase (PI3K)/protein kinase B (Akt) signalling However, mechanism underlying pro‑apoptotic...
FH535 is a small-molecule inhibitor of the Wnt/β-catenin signaling pathway, which substantial body evidence has proven activated in various cancers, including pancreatic cancer. Activation pathway plays an important role tumor progression and metastasis. We investigated inhibitory effect on metastasis growth cancer cells. Western blotting luciferase reporter gene assay indicated that markedly inhibited viability In vitro wound healing, invasion, adhesion assays revealed significantly cell...
The aim of the present study was to evaluate efficacy targeted nursing for patients with systemic lupus erythematosus (SLE). A total 114 clinically diagnosed stable SLE were prospectively selected. randomly divided into regular special group, comprising 56 and group (i.e., taylor made according different pathogenic conditions treatment period), 58 patients. received standard medical SLE, irrespective their on disease activity, incidence complications, therapeutic compliance, quality life...
Numerous nanocarriers with excellent biocompatibilities have been used to improve cancer therapy. However, nonspecific protein adsorption of may block the modified nanoparticles in tumor cells, which would lead inefficient cellular internalization. To address this issue, pH-responsive polyurethane prodrug micelles a zwitterionic segment were designed and prepared. The micelle consisted as hydrophilic shell drug Adriamycin (DOX) hydrophobic inner core. As antitumor delivery system, showed...
Abstract Early detection of pancreatic ductal adenocarcinoma (PDAC) is essential for survival. Preliminary research demonstrated significant associations between structural alternation mycobiota and PDAC. In this study, we investigated the oral We further explored biomarkers PDAC detection. enrolled 34 patients 35 matched healthy controls from West China hospital in Southwest China. Demographic data, clinical information, salivary samples were collected. Mycobiota characteristics defined...
Abstract Background The postoperative analgesic effect of transmuscular quadratus lumborum block (QLB-TM) in patients following lower abdominal surgeries has been identified; however, the efficacy QLB using lateral approach (QLB-L) is still debate. Therefore, this retrospective study was conducted to investigate a single-shot with QLB-L on analgesia for undergoing percutaneous nephrolithotomy (PCNL). Methods medical information PCNL retrieved from electronic charter system (Medisystem,...
The risk factors for patients with major postoperative complications immediately after liver resection have been identified; however, the intermediate and long-term prognoses these yet to be determined.