A5072147563- Plant Disease Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Plant Pathogenic Bacteria Studies
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Biofuel production and bioconversion
- Animal Genetics and Reproduction
- Polysaccharides and Plant Cell Walls
- Enzyme Production and Characterization
John Innes Centre
2021-2025
Agricultural soil harbors a diverse microbiome that can form beneficial relationships with plants, including the inhibition of plant pathogens. Pseudomonas spp. are one most abundant bacterial genera in and rhizosphere play important roles promoting health. However, genetic determinants this activity only partially understood. Here, we genetically phenotypically characterize fluorescens population commercial potato field, where identify strong correlations between specialized metabolite...
The natural products actinonin and matlystatin feature an N -hydroxy-2-pentyl-succinamyl (HPS) chemophore that facilitates metal chelation confers their metalloproteinase inhibitory activity. Actinonin is the most potent inhibitor of peptide deformylase (PDF) exerts antimicrobial herbicidal bioactivity by disrupting protein synthesis. Here, we used a genomics-led approach to identify candidate biosynthetic gene clusters (BGCs) hypothesized produce HPS-containing products. We show one these...
ABSTRACT The natural products actinonin and matlystatin feature an N -hydroxy-2-pentyl-succinamyl (HPS) chemophore that facilitates metal chelation confers their metalloproteinase inhibitory activity. Actinonin is the most potent inhibitor of peptide deformylase (PDF) exerts antimicrobial herbicidal bioactivity by disrupting protein synthesis. Here, we used a genomics-led approach to identify candidate biosynthetic gene clusters (BGCs) hypothesised produce novel HPS-containing products. We...
Abstract Agricultural soil harbors a diverse microbiome that can form beneficial relationships with plants, including the inhibition of plant pathogens. Pseudomonas spp. are one most abundant bacterial genera in and rhizosphere play important roles promoting health. However, genetic determinants this activity only partially understood. Here, we genetically phenotypically characterize fluorescens population commercial potato field, where identify strong correlations between specialized...