- Advanced biosensing and bioanalysis techniques
- Microbial Metabolic Engineering and Bioproduction
- Electrochemical Analysis and Applications
- Enzyme Catalysis and Immobilization
- Advanced Nanomaterials in Catalysis
- Metal-Organic Frameworks: Synthesis and Applications
- Biosensors and Analytical Detection
- Protein Structure and Dynamics
- Nanocluster Synthesis and Applications
- RNA Interference and Gene Delivery
- Electrochemical sensors and biosensors
- TiO2 Photocatalysis and Solar Cells
- Biochemical and Molecular Research
- Plant biochemistry and biosynthesis
- Mathematical Biology Tumor Growth
- Gene Regulatory Network Analysis
- Advanced Photocatalysis Techniques
Tianjin University
2019-2025
Southwest University
2017-2018
Jiangnan University
2016-2017
Dalian University of Technology
2017
State Key Laboratory of Food Science and Technology
2016
In this work, an improved target-triggering nicking enzyme signaling amplification (NESA) strategy as signal enhancer has been fabricated to obtain a sensitive electrochemical thrombin (TB) biosensor combined with PtPd NPs decorated electroactive Co-based metal–organic frameworks (Co-MOFs/PtPdNPs) redox mediator. Traditionally, in the NESA strategy, only one of output double strands DNA is available next cycle. However, all involved strategies could be further employed, resulting high...
In this work, we prepared advanced upconversion nanoparticle coated with TiO2 photocatalysts (NaYF4:Yb,Tm@TiO2) to utilize not only UV energy but also the large portion of NIR in order improve utilization efficiency solar lights. The MC-LR (10 μg/mL) degradation rate can be approached 100% within 30 min at concentration NaYF4:Yb,Tm@TiO2 0.4 mg/mL and initial pH value 4, while 61%, using pure (P25) under simulated reaction processes were studied fitted pseudo-first-order kinetic model. Highly...
(R)-3-aminobutyric acid is an important raw material for dolutegravir production, which a key antiretroviral medicine AIDS treatment. Currently, the industrial production of relies on chiral resolution methods, are plagued by high pollution and low yield efficiency. Here, we report efficient pathway via engineered aspartase-driven biotransformation in recombinant E. coli. The aspartase mutants, obtained through rational design based catalytic mechanisms, were specifically employed to...
In this work, a novel electrochemical assay was constructed based on acid-induced dissolution of nanoparticles to trigger enzyme-free cleavage for thrombin (TB) detection. First, the magnetic bioconjugates Fe3O4/Au/s1 could link with ZnO/Au/TBA via complementary base pairing. Once target TB introduced in system react binding aptamer (TBA), formed ZnO/Au/TBA/TB biocomplex separate from which be removed by separation and further dissolved acidolysis turn ZnO (ZnO NPs) into Zn2+. Finally,...
In this paper, we consider a nonlinear non-differentiable dynamic system in microbial continuous cultures involving all possible metabolic pathways of the inhibition mechanisms 3-hydroxypropionaldehyde onto cell growth and transport systems glycerol 1,3-PD across membrane. First, existence equilibrium point proved. And by numerical calculation, is obtained. Subsequently, derive local bounded properties Jacobian, tensor Hessian matrices system. Finally, asymptotical stability at