A5100647907- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Lung Cancer Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Lung Cancer Treatments and Mutations
- Childhood Cancer Survivors' Quality of Life
- Cancer Immunotherapy and Biomarkers
- Cancer survivorship and care
- Lung Cancer Research Studies
- Coastal and Marine Dynamics
- Mycobacterium research and diagnosis
- Palliative Care and End-of-Life Issues
- SARS-CoV-2 detection and testing
- COVID-19 and healthcare impacts
- Advanced biosensing and bioanalysis techniques
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Antifungal resistance and susceptibility
- Gastric Cancer Management and Outcomes
- Cardiovascular Function and Risk Factors
- Microbial Metabolism and Applications
- COVID-19 Clinical Research Studies
- Ocean Waves and Remote Sensing
- Limits and Structures in Graph Theory
- Graph Labeling and Dimension Problems
Peking University People's Hospital
2013-2025
Peking University
2013-2025
Roswell Park Comprehensive Cancer Center
2013-2025
Jacobs (United States)
2025
National Chung Hsing University
2001-2024
Fujian Medical University
2022-2024
Fujian Provincial Cancer Hospital
2024
Wuhan University
2005-2023
Renmin Hospital of Wuhan University
2009-2023
Union Hospital
2022-2023
Abstract BACKGROUND To the authors' knowledge, few data currently are available regarding tolerance to chemotherapy in older cancer patients. This prospective pilot study evaluated changes functional, mental, nutritional, and comorbid status, as well quality of life (QOL), geriatric oncology patients receiving chemotherapy. METHODS Sixty age ≥ 70 years who were undergoing recruited a university‐based comprehensive center. Changes physical function measured by Eastern Cooperative Oncology...
Methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) is a serious problem worldwide. To investigate the molecular epidemiology of MRSA isolates in China, total 702 collected from 18 teaching hospitals 14 cities between 2005 and 2006 were characterized by antibiogram analysis, pulsed-field gel electrophoresis (PFGE), staphylococcal cassette chromosome mec (SCCmec) typing, spa typing; 102 selected for multilocus sequence typing (MLST). Overall, SCCmec type III was most popular found...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in six epidemic provinces of China and was identified to be caused by a novel bunyavirus 2009. It progressive nature potentially fatal. SFTS usually occurs as sporadic cases considered tick-transmitted disease. Here we present group three patients proven one probable SFTS, for whom the epidemiological data show person-to-person transmission characteristics. The index patient two secondary died. None reported...
The incidence of methicillin-resistant Staphylococcus aureus (MRSA) has been increasing yearly at Peking Union Medical College Hospital (PUMCH). In order to understand the molecular evolution MRSA PUMCH, a total 466 nonduplicate S. isolates, including 302 and 164 methicillin-susceptible (MSSA) isolates recovered from 1994 2008 were characterized by staphylococcal cassette chromosome mec (SCCmec) typing, spa pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST)....
To investigate the epidemiology and genetic structure of Staphylococcus aureus bacteremia in China, a total 416 isolates from 22 teaching hospitals 12 cities 2013 2016 were characterized by antibiogram analysis, multilocus sequence typing (MLST), spa staphylococcal cassette chromosome mec (SCCmec) typing. The predominant meticillin-susceptible (MSSA) genotypes ST188 (19.1%), ST7 (8.7%) ST398 (7.8%), respectively, they continued to be main 2016. prevalence meticillin-resistant S. (MRSA) 36.5%...
Abstract Objectives Available literature documents that ischemic stroke can disrupt the morphology and function of mitochondria latter in other disease models be preserved by neuropilin-1 (NRP-1) via oxidative stress suppression. However, whether NRP-1 repair mitochondrial structure promote functional recovery after cerebral ischemia is still unknown. This study tackled this very issue explored underlying mechanism. Methods Adeno-associated viral (AAV)-NRP-1 was stereotaxically inoculated...
A view often held in Europe is that older Europeans are less willing than Americans to undertake chemotherapy. This study assesses whether this valid.Three-hundred twenty outpatients aged 70 years and were interviewed via anonymous questionnaires: French patients with without cancer American cancer. The response rate was 61% (195 of 320 questionnaires). Ages ranged from 95 (29% 80 older). Two scenarios presented: a strong chemotherapy (platinum/taxane combination-like) milder (weekly...
Patients with lung cancer have the poorest sleep quality compared other patients and noncancer control subjects. However, few studies examined longitudinally.The objective of this study was to characterize correlate quality, daytime sleepiness, sleep-wake actigraphy, life (QOL) before, during, after chemotherapy for non-small cell (NSCLC).Using a prospective repeated-measures 1-group design, scheduled receive NSCLC were recruited. Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale,...
Background: Early detection of infected patients is one the most important steps to mitigate spreading 2019 novel coronavirus (2019-nCoV). Here, we report a set atypical 2019-nCoV pneumonia cases with gastrointestinal symptoms onset but without fever or other respiratory symptoms.Methods: We retrospectively reviewed data admitted only digestive and no on from January 17-24, in Renmin Hospital Wuhan University. The patients' history, clinical features, physical findings, complete blood count,...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen subdivided into lineages termed sequence types (STs). Since the 1950s, successive waves of STs have appeared and replaced previously dominant lineages. One such event has been occurring in China since 2013, with community-associated (CA-MRSA) strains including ST59 largely replacing healthcare-associated (HA-MRSA) ST239. We showed that isolates tend to competitive advantage growth experiments against However,...
With the reduction in sequencing price and acceleration of speed, it is particularly important to directly link genotype phenotype bacteria. Here, we firstly predicted minimum inhibitory concentrations ten antimicrobial agents for Staphylococcus aureus using 466 isolates by extracting k-mer from whole genome data combined with three machine learning algorithms: random forest, support vector machine, XGBoost. Considering one two-fold dilution, essential agreement category could reach >85%...
OBJECTIVES: To identify factors that may influence the decision of whether to enter a hospice program or continue with traditional hospital approach in patients advanced cancer and understand their decision‐making process. DESIGN: Cross‐sectional structured interview. SETTING: One community‐based three university‐based teaching hospitals. PARTICIPANTS: Two hundred thirty‐four adult diagnosed lung, breast, prostate, colon life expectancy less than 1 year: 173 61 nonhospice receiving care....
Background: An outbreak and worldwide spread of COVID-19 was derived from Wuhan, China where over half the confirmed cases were reported. Protection for special populations at high infection risk such as patients with inflammatory bowel diseases (IBD) is extremely urgent challenging. Methods: We kept alerts since first reported case started to send educational instructional took measures 318 registered IBD (204 UC 114 CD) 20 days earlier shutdown Wuhan. The patients' risks, responses our...
Marked increases in fluconazole resistance Candida tropicalis have been recently reported. In this study, the molecular mechanisms behind were investigated. Twenty-two C. clinical isolates, including 12 fluconazole-resistant isolates and 10 fluconazole-susceptible collected from a tertiary care teaching hospital Beijing between 2013 2017. Antifungal susceptibility testing, multilocus sequence typing, ERG11 amplification sequencing, quantitative real-time reverse transcription-polymerase...
Family members are involved in every aspect of end-of-life decision making and care. The present article reviews family involvement providing care during chronic terminal illness, discussions plans for advance directives, executing directives critical decisions near the end life, long-lasting effects caregiving difficult on member bereavement. Although legal standards much research life emphasize individual value autonomy, should be increasingly understood within a context. There is also...