A5101762285- Chinese history and philosophy
- Neurological Disease Mechanisms and Treatments
- Mosquito-borne diseases and control
- Cerebrovascular and Carotid Artery Diseases
- Antibiotic Resistance in Bacteria
- Viral Infections and Vectors
- Neuroinflammation and Neurodegeneration Mechanisms
- interferon and immune responses
- Mitochondrial Function and Pathology
- Escherichia coli research studies
- Pharmacological Effects of Natural Compounds
- Flannery O'Connor and Thomas Merton
- Urological Disorders and Treatments
- Economic Development and Digital Transformation
- Drug-Induced Hepatotoxicity and Protection
- High Altitude and Hypoxia
- Heart Failure Treatment and Management
- China's Ethnic Minorities and Relations
- Rabies epidemiology and control
- Joseph Conrad and Literature
- Herbal Medicine Research Studies
- Innovation Policy and R&D
- Advanced Technologies in Various Fields
- Monoclonal and Polyclonal Antibodies Research
- Cancer Mechanisms and Therapy
Xi'an Institute of Optics and Precision Mechanics
2025
Chinese Academy of Sciences
2025
Affiliated Hospital of Nantong University
2025
Nantong University
2006-2025
Qingdao University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2022
Siberian Federal University
2022
Sanya Central Hospital
2020
Academy of Military Medical Sciences
2019
Air Force Medical University
2017
A new antibody platform combining anti-Psl and anti-PcrV activities provides enhanced protection acts synergistically with antibiotics against Pseudomonas aeruginosa .
Abstract Emerging multidrug-resistant bacteria are a challenge for modern medicine, but how these pathogens so successful is not fully understood. Robust antibacterial vaccines have prevented and reduced resistance suggesting pivotal role immunity in deterring antibiotic resistance. Here, we show the increased prevalence of Klebsiella pneumoniae lipopolysaccharide O2 serotype strains all major drug groups correlating with paucity anti-O2 antibodies human B cell repertoires. We identify...
Intestinal ischemia reperfusion injury is a frequent clinical damage, in which the oxidative stress and inflammation play an important role. Interleukin-1 receptor antagonist (IL-1Ra) natural anti-inflammatory factor, however, its effect on intestinal remains unclear. The rat model of I/R was induced by occlusion (for 60 min) reopening superior mesenteric artery. rats were randomly divided into following 5 groups: sham-operation(S), (I/R),10 mg/kgIL-1Ra + (C1),20 (C2), and30 (C3). In this...
Traumatic neuronal injury (TNI), a type of traumatic brain (TBI), features apoptosis cortical neurons. Knowing that docosahexaenoic acid (DHA) is enriched in the cell membranes and related to function, we aimed study mechanism behind effect DHA on TNI model Neurons were derived from Sprague-Dawley rats was established by using rotating scribe device. Four experimental groups set up based concentration, namely Control, TNI, + DHA-25, DHA-50 groups. The morphology, toxicity neuron assessed...
Background. The type 3 secretion protein PcrV and Psl exopolysaccharide are promising therapeutic antibody targets against Pseudomonas aeruginosa. We examined P. aeruginosa bloodstream infection (BSI) isolates for the ability to express evaluated corresponding patient serum active titers these targets.
The care of major trauma patients continues to be a challenge for emergency physicians and surgeons. We found that the total number radiological examinations in this study was high mainly comprised radiography computed tomography (CT), with CT being more commonly adopted. scans positively correlated severity injury intensive unit length stay. Further is warranted optimize involving patients.
<h3>Objective</h3> Drug eluting stent (DES) with percutaneous coronary intervention is increasingly used to treat unprotected left main artery (LMCA) disease. We undertook a meta analysis assess outcomes for bypass graft (CABG) and DES LMCA <h3>Methods</h3> conducted PubMed/EMBASE/CENTRAL search RCTs evaluating CABG versus LMCA. Primary outcome was survival. Secondary were major adverse cardiac cerebrovascular event (MACCE) target vessel revascularization (TVR). <h3>Results</h3> Four...
Objective To investigate the technical details, safety, feasibility and clinical results of endovascular recanalization for non-acute internal carotid artery occlusion. Methods A retrospective analysis was conducted in 13 patients with occlusion who underwent revascularization from June 2015 to May 2016 at Department Neurosurgery, TEDA Hospital. The aspects procedure angiographic predictors success were analyzed. Results The occluded successfully recanalized 12 (92%). There no...
Objective To evaluate the safety and feasibility of balloon guide catheter (BGC) in recanalization intracranial internal carotid artery occlusion. Methods Retrospective analysis was conducted 7 patients with non-acute symptomatic occlusion who underwent endovascular revascularization under protection BGC our hospital from March 2016 to August 2016. The duration ranged 3 weeks one year mean time 22 weeks. technical aspects using were analyzed. Results Recanalization successful...