A5009215427- Neonatal and Maternal Infections
- Maternal and Neonatal Healthcare
- Infant Development and Preterm Care
- Global Maternal and Child Health
- Pneumonia and Respiratory Infections
- HIV Research and Treatment
- Neonatal and fetal brain pathology
- Adolescent and Pediatric Healthcare
- Poverty, Education, and Child Welfare
- Child and Adolescent Health
- Streptococcal Infections and Treatments
- Bacterial Infections and Vaccines
- HIV/AIDS Research and Interventions
- Autism Spectrum Disorder Research
Chris Hani Baragwanath Hospital
2025
University of the Witwatersrand
2012-2025
Neurodevelopmental delay has been documented in up to 97.5% of HIV-infected children Soweto who were not yet on antiretroviral treatment (ART). With growing numbers South Africa being successfully treated with ART, the effects ART neurocognitive functioning require investigation. The objective this study was determine extent neurodevelopmental stable preschool (aged five six years) receiving and compare it an apparently healthy (unconfirmed HIV-status) group children. Thirty (virologically...
Background Developmental paediatrics is a growing field both globally and locally with increasing demand for medical educational resources. Methods This retrospective, developmental database review baseline description of the Chris Hani Baragwanath Academic Hospital neurodevelopmental clinic population, service offered over past 4 years. The population comprises all patients seen at from May 2020 to December 2024. Outcomes measured were total patient numbers, demographic, clinical management...
Data are limited regarding long-term consequences of invasive GBS (iGBS) disease in early infancy, especially from low- and middle-income countries (LMIC) where most cases occur. We aimed to estimate risk neurodevelopmental impairment (NDI) children with a history iGBS disease.
Survivors of invasive group B Streptococcus (iGBS) disease, notably meningitis, are at increased risk neurodevelopmental impairment. However, the limited studies to date have a median follow-up 18 months and mainly focused on moderate or severe impairment, with no previous emotional-behavioral problems among iGBS survivors.In this multicountry, matched cohort study, we included children aged 17 years infant sepsis meningitis from health demographic surveillance systems, hospital records in...
Invasive group B Streptococcus (iGBS) sepsis and meningitis are important causes of child mortality, but studies on neurodevelopmental impairment (NDI) after iGBS limited. Using Griffiths Mental Development Scales-Extended Revised (GMDS-ER), we described NDI in survivors non-iGBS children from South Africa, as part a 5-country study.
<ns4:p>Sepsis and meningitis due to invasive group B <ns4:italic>Streptococcus</ns4:italic> (iGBS) disease during early infancy is a leading cause of child mortality. Recent systematic estimates the worldwide burden GBS suggested that there are 319,000 cases infant iGBS each year, an estimated 147,000 stillbirths young-infant deaths, with highest occurring in Sub-Saharan Africa. The following priority data gaps were highlighted: (1) long-term outcome after iGBS, including mild disability,...
<ns4:p>Sepsis and meningitis due to invasive group B <ns4:italic>Streptococcus</ns4:italic> (iGBS) disease during early infancy is a leading cause of child mortality. Recent systematic estimates the worldwide burden GBS suggested that there are 319,000 cases infant iGBS each year, an estimated 147,000 stillbirths young-infant deaths, with highest occurring in Sub-Saharan Africa. The following priority data gaps were highlighted: (1) long-term outcome after iGBS, including mild disability,...