ABSTRACT Objective Cognitive impairment is increasingly recognized as a complication of diabetes, yet the underlying pathology remains unclear. This study aims to investigate roles inflammation, oxidative stress, endothelial dysfunction, and neuronal damage in neuropathology diabetes related cognitive impairment. Methods assessed 183 participants (54 prediabetes, 71 Type 2 mellitus [T2DM], 58 controls) for performance using Montreal Assessment (MoCA). Blood samples were analyzed...

Aim Clinical and epidemiological studies suggest links between dementias Type 2 diabetes (T2DM). The underlying mechanisms of diabetes-related cognitive impairment are largely unknown. This study aims to investigate the role BDNF in prediabetes T2DM. Methods included 68 patients with (preDM), 96 T2DM, 65 healthy controls. function was evaluated Montreal Cognitive Assessment (MoCA) test serum levels were measured by Elisa. MoCA scores compared groups after adjusting for age, gender, education...

Aim: This study investigates the structural effects of repetitive transcranial magnetic stimulation (rTMS) on hippocampal subfields and cortical shape metrics in Alzheimer’s disease (AD) patients. Using high-resolution MRI segmentation analysis via Hippunfold, we aim to elucidate TMS-induced changes assess its potential neuroprotective role. Methods: retrospective included 17 AD patients 18 healthy controls (HC). underwent 20 Hz rTMS targeting left lateral parietal cortex over 10 sessions...

ABSTRACT Objectives The aim of this study was to investigate among caregivers older hospitalized patients, the relationship between caregiver burden, caregivers' nutrition, and two most common sleep disorders—excessive daytime sleepiness insomnia—as well as interplay these factors. Method universe consisted informal inpatients at an university hospital in Turkiye. sample included 100 selected through purposive sampling March 2024‐/January 2025. Data were collected on personal information,...

Introduction The use of psychostimulant drugs to increase academic success is common among young people. There no study examining this issue in Turkish population. In study, the prevalence, attitudes, knowledge, and ethical evaluations Pharmacological Cognitive Enhancement (PCE) university students were investigated. Method A structured online survey was carried out with 1148 undergraduate postgraduate (master, PhD residency) different faculties Medicine, Dentistry Pharmacy Turkey....

Introduction: Anticholinergic burden may be an important risk factor for the cognitive impairment. Especially in polypharmacy, even drugs with low anticholinergic effects contribute to a significant burden. The are used treatment of motor and nonmotor symptoms Parkinson’s disease (PD). Therefore, it is screen polypharmacy PD patients mild impairment (MCI). Methods: This cross-sectional study was conducted 58 PD. PD-MCI diagnosed according MDS Level 2 Comprehensive Assessment. Cognitive...

Abstract Aim Although there exists substantial epidemiological evidence indicating an elevated risk of dementia in individuals with diabetes, our understanding the neuropathological underpinnings association between Type‐2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) remains unclear. This study aims to unveil microstructural brain changes associated T2DM AD identify clinical variables contributing these changes. Methods In this retrospective involving 64 patients AD, 31 had...

Objective: It is well-known that healthy medical students use psychostimulants to improve their cognitive functions and reduce need for sleep. The main motivation behind this enhancement increase academic performance. However, the literature not clear enough support situation. Methods: This cross-sectional study was conducted with an online survey 585 participated. grade point average number used assess student' Additionally, scale based on self-evaluations levels of pharmaceutical...

Cognitive impairment is frequently seen in patients with type 2 diabetes (T2DM), ranging from mild to dementia. However, our knowledge of the specific profiles and risk factors for these different levels limited. In this study involving 152 T2DM, cognitive function was assessed using Montreal Assessment test. The Fuzzy C-means clustering algorithm utilized group individuals similar characteristics. evaluated how well clinical parameters could classify characteristics clusters Classification...

Objective: It is important to monitor and manage macrovascular microvascular complications, which are significant causes of mortality morbidity in type 2 diabetes (T2DM). Diabetes-related cognitive impairment an complication that has recently attracted more attention, but its pathophysiology clinical features not known. The aim this study was evaluate the potential role inflammation diabetes-related impairment. Material Method: A total 122 participants (67 patients with T2DM 55 controls)...

Tedavi uyumuna dair literatürde 'compliance', 'adherence' ve 'concordance' gibi farklı kavramlar kullanılmaktadır. İngilizce söz konusu kavramlarda görülen değişimin hasta-hekim ilişkisinin yapısındaki farklılaşmaya bağlı olduğu bildirilmektedir. Bu konuda terimlerin bulunması nedeni ile karmaşıklık yaşanmakta, kavramın nitelik nicelik olarak kapsamı hususunda muğlaklık bulunmaktadır. Türkçe literatür değerlendirildiğinde ise bu terimler arasında anlam farkı gözetilmeksizin tümünün uyum...

Aim: This study aims to evaluate the influence of Coronavirus Disease-19 (COVID-19) on frequency emergency admissions for ischemic stroke among both young and general populations at a university hospital in Turkey.
 
 Methods: An interrupted time series analysis was employed this study, utilizing retrospectively collected data from Bezmialem Vakıf University Hospital system. The included patients who visited department May 2019 February 2023 were diagnosed with stroke. Results:...